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Pilot study suggests ways to widen access to fecal transplants for C. diff infections
Date:4/23/2014

must take to provide it to patients.

For their first administration, patients were assigned to one of two delivery methods, using either a colonoscope or a nasogastric tube, inserted in the nose and down into the stomach. Both appeared to be equally effective. Patients who required a second infusion were allowed to choose between the two methods, and all five chose the nasogastric tube.

"Colonoscopy is a significant procedure requiring sedation," said Elizabeth L. Hohmann, MD, of MGH and a study co-author, while the nasogastric tube method "is an outpatient office procedure."

The study's findings suggest the latter would be a "cost-effective, upper gastrointestinal route" for transplantation, Dr. Hohmann said, particularly for elderly or debilitated patients who may not tolerate a colonoscopy. The researchers are now studying placing the donated material into a frozen capsule, which patients would take orally.


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Contact: Jerica Pitts
jpitts@pcipr.com
312-558-1770
Infectious Diseases Society of America
Source:Eurekalert

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