Navigation Links
Pilot study suggests ways to widen access to fecal transplants for C. diff infections
Date:4/23/2014

Using frozen stool from healthy, unrelated donors was safe and effective in treating patients with serious, relapsing diarrhea caused by Clostridium difficile, according to a new pilot study published in Clinical Infectious Diseases and available online. Known as fecal microbiota transplantation, the treatment was equally effective whether given via a colonoscope or a nasogastric tube. The findings suggest approaches that may make this promising treatment more readily available to patients.

A growing concern, C. difficile causes 250,000 infections requiring hospitalization and 14,000 deaths in the U.S. each year, according to the Centers for Disease Control and Prevention. Infection incidence has tripled in the last 15 years and is responsible for at least $1 billion in excess U.S. medical costs per year.

In an initial feasibility study, Ilan Youngster, MD, and colleagues at Massachusetts General Hospital (MGH) treated 20 patients suffering from repeated episodes of C. difficile infection with fecal microbiota transplantation, which helps restore the normal balance of bacteria in the affected person's gut. Fourteen of the patients were cured after one administration of donated stool. Of the remaining six patients, five received a second administration, and four were cured, for an overall cure rate of 90 percent.

Unlike previous studies, which used fresh stools from donors, the team at MGH worked with frozen material from unrelated donors who had been recruited and screened well ahead of time, a "banking" approach that may help overcome current treatment barriers. "Establishing a repository of prescreened frozen donor stools could make this treatment available for a wider population," the authors noted, as donor recruitment and screening can be lengthy and costly. The Food and Drug Administration is currently determining how it will regulate fecal microbiota transplantation, including what steps clinicians
'/>"/>

Contact: Jerica Pitts
jpitts@pcipr.com
312-558-1770
Infectious Diseases Society of America
Source:Eurekalert

Page: 1 2

Related medicine news :

1. JHU Bioethics Institute receives PCORI pilot project award
2. Pilot facility launched in Ghana to transform human waste into renewable biodiesel fuel
3. St. Louis Rams Seek Flawless Execution® Training from Fighter Pilots to Take Back Season
4. Research Foundation for Tick-Borne Infections Fights Lyme Disease, Babesiosis and Encephalitis with Pilot Studies
5. Former Military Pilot and Vice President of LifeWings to Speak at MEDNAX
6. Educational First Steps Officially Inducts Five Pilot Child Care Centers into Four Steps to Excellence 2.0 Program
7. To Stop Medical Mistakes, TOPGUN Fighter Pilot Shares Hidden Technology Secrets With Operating Room Staff At National Medical Convention
8. Penn pilot study: Group of Bradford Co, Pa. residents concerned about health effects of hydrofracking
9. Teen girls less successful than boys at quitting meth in UCLA pilot research study
10. Rock The Path Chosen To Pilot Conscious Aging Program Series
11. Hospitals Take Flight Lessons from Pilots to Avoid Government Penalties
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... 27, 2014 Lighthouse Payment Services ... announced that it will exhibit its image-based lockbox services ... 41st annual convention in beautiful Lake Placid, New ... event will be held at the Lake Placid Convention ... and entertainment options in addition to a variety of ...
(Date:8/27/2014)... 2014 Aspirus Wausau Hospital today announced ... with Buzz™ Digital O.R. at Aspirus Wausau Hospital, in ... new operating rooms will be Buzz, a centralized surgical ... system supports planning, navigation, imaging and communications connectivity. ... intuitive software and hardware all controlled from the full ...
(Date:8/27/2014)... Health care workers in poor nations often do not ... being infected with blood-borne viruses such as Ebola and ... was conducted before the current Ebola outbreak began in ... statistics released Monday by the World Health Organization (WHO). ... number of health care workers have lost their lives ...
(Date:8/27/2014)... Stroke patients are 70 per cent more likely to ... if they have a prescription in hand when discharged ... and the Institute for Clinical Evaluative Sciences (ICES). , ... many Ontarians were taking their medications one week, one ... results reveal the importance of simple interventions, such as ...
(Date:8/27/2014)... Chino Hills, CA (PRWEB) August 27, 2014 ... boot camp franchise in the world, the leading fitness ... to Spike TV’s Gym Rescue reality series. One thing he ... personal brand as a subject matter expert in the fitness ... uploaded to YouTube, he lays out a step-by-step instructional guide ...
Breaking Medicine News(10 mins):Health News:Aspirus Wausau Hospital Announces First Large Scale Digital Operating Room Integration Project in the US 2Health News:Aspirus Wausau Hospital Announces First Large Scale Digital Operating Room Integration Project in the US 3Health News:Lack of Protective Gear Leaves Medics at Risk in Ebola Outbreak: Study 2Health News:Lack of Protective Gear Leaves Medics at Risk in Ebola Outbreak: Study 3Health News:A prescription for better stroke care 2Health News:Bedros Keuilian Releases New Fitness Boot Camp Marketing Webinar on Building a Personal Brand 2Health News:Bedros Keuilian Releases New Fitness Boot Camp Marketing Webinar on Building a Personal Brand 3
... , ... Fresh Look at Coping with Multiple Sclerosis through Community , ... (PRWEB) April 13, 2010 -- Motivational Speaker/MS ... guidebook for those newly diagnosed with Multiple Sclerosis. , , ,Published by iUniverse ...
... likely to develop, die from disease , TUESDAY, April 13 ... comes to both developing and dying from lung cancer. , ... grim picture of how environmental factors, biological factors, cultural attitudes ... deadly disease even deadlier among members of this minority group. ...
... ... patients and may be covered by medical insurance will be provided by Khanna institute in ... (Vocus) April ... with countless solutions for eye and sight problems, hereby announces that it is offering its ...
... mutated gene in human cancers is the reitnoblastoma (RB) gene, ... gene disable the vast and intricate RB pathway in virtually ... cellular functions and ultimately provoking cancer. But which of these ... uncertain. "We have now found that a key function ...
... ... general availability of ActiveStrategy iRound™, which enables field-level performance management data to be ... Enterprise software. , ... (PRWEB) April 13, 2010 -- ActiveStrategy, the leading provider of comprehensive ...
... on failure rates could aid surgeons who import donor tissue, ... a corneal transplant will fail is not affected by the ... transplanted cornea was preserved or the method of preservation, according ... study that included 388 people who were followed for up ...
Cached Medicine News:Health News:Author Erin Morrow Still Releases "Fighting MS: Strength in Numbers" 2Health News:Author Erin Morrow Still Releases "Fighting MS: Strength in Numbers" 3Health News:Blacks Hit Hardest by Lung Cancer 2Health News:Blacks Hit Hardest by Lung Cancer 3Health News:Khanna Institute to Provide Intacs Corneal Implants in Beverly Hills 2Health News:Khanna Institute to Provide Intacs Corneal Implants in Beverly Hills 3Health News:CSHL scientists discover how a tumor suppressor induces senescence and staves off cancer 2Health News:ActiveStrategy iRound™ is Launched to Enable Seamless Capture of Field-Level Performance Management Data 2Health News:ActiveStrategy iRound™ is Launched to Enable Seamless Capture of Field-Level Performance Management Data 3Health News:Corneal Transplant Not Hurt by Long Preservation Time 2
(Date:8/27/2014)... 2014 Ambit Biosciences (Nasdaq: AMBI ), a ... unmet needs in oncology, autoimmune and inflammatory disease, today announced ... to be held at The New York Palace Hotel in ... 2014. Alan Fuhrman , Ambit,s CFO, will ... candidate, quizartinib, at 1:10 p.m. ET on Wednesday, September 3, ...
(Date:8/27/2014)... Pa. , Aug. 27, 2014   Auxilium Pharmaceuticals ... integrated specialty biopharmaceutical company, today announced that certain members ... Morgan Stanley Healthcare Conference to be held September 8-10, ... Adrian Adams , Chief Executive Officer and President, is ... its product portfolio at 10:55 a.m. ET on Wednesday, ...
(Date:8/26/2014)... , Aug. 27, 2014 Higher ... insurance are fuelling the demand for medical devices ... rise of medical tourism, the inflow of patients ... The market will continue its steady ascent as ... age-related and non-communicable diseases, compelling significant investments in ...
Breaking Medicine Technology:Ambit Announces Participation At Baird 2014 Health Care Conference 2Auxilium Pharmaceuticals, Inc. To Present At The Morgan Stanley Healthcare Conference 2Auxilium Pharmaceuticals, Inc. To Present At The Morgan Stanley Healthcare Conference 3Frost & Sullivan: Change in Demographics and Surge in Domestic Manufacturing Drive Asia-Pacific Medical Devices Market 2Frost & Sullivan: Change in Demographics and Surge in Domestic Manufacturing Drive Asia-Pacific Medical Devices Market 3Frost & Sullivan: Change in Demographics and Surge in Domestic Manufacturing Drive Asia-Pacific Medical Devices Market 4
... Antibody (IgM) Test is an ... quantitative detection of antibodies to ... is used as an aid ... thrombosis in individuals with systemic ...
The 8500 is an extremely reliable portable pulse oximeter, requiring no periodic maintenance or calibration....
Rad-5v signal extraction pulse oximeter™...
... The 8500 Digital Handheld ... universal tool for patients monitoring ... continuous monitoring. As the first ... as a benchmark for durability ...
Medicine Products: