Navigation Links
Pilot Study to Assess Safety and Efficacy of Medidur(TM) FA in AMD Patients Treated With Lucentis(R)
Date:5/8/2008

ATLANTA, May 8 /PRNewswire/ -- Alimera Sciences Inc., a privately held ophthalmic pharmaceutical company announced today that enrollment has begun for a pilot study to assess the safety and efficacy of Medidur FA in conjunction with Lucentis(R) (ranibizumab injection, Genentech) in patients with exudative age-related macular degeneration (wet AMD).

This pilot study, which will be performed under an investigator sponsored IND, will compare two doses of Medidur FA (0.2 and 0.5 ug/day) in patients who have been treated with Lucentis for at least six months. The change from baseline in parameters such as visual acuity and retinal thickness will be assessed, in addition to comparing the number of Lucentis injections post- randomization versus pre-randomization. It has been previously shown that Lucentis requires persistent dosing to maintain efficacy.

"Alimera Sciences is pleased to support this study design because it will provide preliminary information on the potential of Medidur FA to maintain the efficacy established with Lucentis while reducing the number of Lucentis treatments," said Dr. Ken Green, Senior VP and Chief Scientific Officer for Alimera Sciences.

Lucentis is an antibody that binds to VEGF, thus preventing it from interacting with its receptor and causing additional damage in patients with wet AMD. Corticosteroids inhibit VEGF secretion in addition to their anti- inflammatory action and ability to suppress leukostasis. Given these complementary actions, the concomitant use of Lucentis and Medidur is warranted in patients being treated with Lucentis for wet AMD.

AMD is a degenerative disease of the central portion of the retina (the macula) which typically occurs in patients over the age of 50. One form of the disease, exudative (or wet) AMD is characterized by the formation of leaky new blood vessels originating in the choroid which may hemorrhage and cause accumulation of sub- and intra-retinal fluid. This form of AMD
'/>"/>

SOURCE Alimera Sciences Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine news :

1. Pilot study reinforces use of portable anteroom HEPA filtration
2. Phyhealth Signs Agreement with Advantica EyeCare to Provide Vision Services for Pilot HMO
3. Lake Hospital System Selected as Pilot Site for Health Information Literacy Research Project
4. NovoCure presents results from breast cancer pilot study
5. Researchers pilot new electronic system for infectious illness
6. VA to Pilot Innovative Remote Benefits Delivery Program
7. Phyhealth Concludes $1.5 Million Financing for Launch of Its Pilot Community-Based HMO
8. GHI and HIP Launch Pilot Medical Home Network Project with Support from Commonwealth Fund
9. Rockefeller Universitys Center for Clinical and Translational Science funds pilot studies
10. Pilot error declines as factor in airline mishaps
11. GDAHC Save Lives Save Dollars Initiative Launches Pilot Program for Diabetes Care Management
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/29/2015)... Final Cut Pro X plugin ... Studios, entitled TranSports. , “TranSports is a compilation ... Pro X,” said Christiana Austin, CEO of Pixel Film ... effortlessly transition using this cool sports transition tool.” , ... styled transition pack for Final Cut Pro X. TranSports ...
(Date:3/28/2015)... March 28, 2015 Could genetic code ... new study by researchers at the Harvard ... with the support of the Coffee and Caffeine Genetics ... Psychiatry this past fall, the study—one of several recent ... genomic data from more than 120,000 regular coffee drinkers ...
(Date:3/28/2015)... The California-based leading wig brand UniWigs has prepared a ... during the Easter Holidays from today until April 6th. ... Fools’ Day. , As the winter fades and spring ... Festival, with religious origins to countries in Europe and ... The best wig provider, UniWigs, would like to offer ...
(Date:3/28/2015)... NV (PRWEB) March 28, 2015 Pitching speed, ... a history of shoulder and elbow injuries, according to new ... Medicine’s ( AOSSM ) Specialty Day. , “Our findings indicate ... a 20% increase in likelihood of a history of injury, ... with a 12% increase likelihood of a history of injury, ...
(Date:3/28/2015)... Raleigh, NC (PRWEB) March 28, 2015 ... people with peritoneal mesothelioma, revealing, for the first time, ... Click here to read the newly posted story ... scientists at the University of British Columbia, the British ... used genome mapping to reveal underlying molecular alterations and ...
Breaking Medicine News(10 mins):Health News:Introducing TranSports for Final Cut Pro X Users from Pixel Film Studios 2Health News:How Coffee Habits Relate to Our Genetic Code and Enhancing the Caffeine Experience 2Health News:How Coffee Habits Relate to Our Genetic Code and Enhancing the Caffeine Experience 3Health News:UniWigs Is Sending Out Mysterious Gifts During the Easter Holidays 2Health News:Researchers Highlight Shoulder and Elbow Injury Possibility in Youth Players 2Health News:New Genomics Research May Help Doctors Tailor Mesothelioma Treatment, According to Surviving Mesothelioma 2
... The increase in the number of U.S. medical students ... sign toward easing the primary care workforce shortage, according ... second-largest doctors group. The 2011 National Resident Matching ... from last year, with 2,940 U.S. seniors at medical ...
... Arbor, Mich. Providing kidney transplants to patients with ... transplant operations and improve life span after kidney transplant, ... the New England Journal of Medicine March 16., Alan ... and his co-authors endorsed new concepts designed to improve ...
... N.J. (March 16, 2011) The Multiple Myeloma Research ... Hackensack University Medical Center, member of the Multiple Myeloma ... in Multiple Myeloma Patient Symposium on Saturday, April 2 ... program is for patients and caregivers who want to ...
... released new official clinical guidelines on the diagnosis ... statement replaces ATS guidelines published in 2000, and ... and management of IPF, as well as available ... palliative care. , The statement appears in the ...
... By Maureen Salamon HealthDay Reporter , ... on Parkinson,s disease patients significantly improved the tremors, rigidity ... the illness, a small new study reports. The ... advanced Parkinson,s disease, with half randomly assigned to receive ...
... shows that it is feasible to screen for undiagnosed ... arrest (SCA). Adding a 10-minute electrocardiogram (EKG or ECG) ... of potentially serious heart conditions. Although more ... relatively low-cost screening might help identify children who are ...
Cached Medicine News:Health News:Residency match results encouraging for adults needing primary care 2Health News:Survival matching should be used to allocate donated kidneys to transplant recipients 2Health News:Survival matching should be used to allocate donated kidneys to transplant recipients 3Health News:The MMRF and John Theurer Cancer Center to host patient symposium 2Health News:ATS issues joint statement on the treatment of idiopathic pulmonary fibrosis 2Health News:ATS issues joint statement on the treatment of idiopathic pulmonary fibrosis 3Health News:ATS issues joint statement on the treatment of idiopathic pulmonary fibrosis 4Health News:Gene Therapy May Help Reverse Parkinson's Symptoms 2Health News:Gene Therapy May Help Reverse Parkinson's Symptoms 3Health News:In pilot study, screening detects potentially serious heart conditions in healthy children 2
(Date:3/27/2015)... 27, 2015 According to a ... Catheter (Conventional, Advanced, Ultrasound), Ablation Catheter (Cryoablation, RF, Microwave), ... (AF, VT, WPW) - Global Forecasts to 2019 ", published ... reach around ~$4.73 Billion by 2019 with a CAGR ... 2019. Browse   90   ma ...
(Date:3/27/2015)... DALLAS , March 27, 2015   ... global leader in biosimilars and the world,s leading ... two studies that support an evaluation of biosimilarity ... U.S. Food and Drug Administration (FDA) conditionally approved ... Amgen,s EPOGEN™ (epoetin alfa). These study data were ...
(Date:3/27/2015)... DALLAS , March 27, 2015 ... Review, H1 2015" therapeutic market research report of ... to its online business intelligence library. ... comprehensive information on the therapeutic development for Visceral ... therapeutics assessment by drug target, mechanism of action ...
Breaking Medicine Technology:Electrophysiology (EP) Market Worth $4.73 Billion by 2019 2Electrophysiology (EP) Market Worth $4.73 Billion by 2019 3Electrophysiology (EP) Market Worth $4.73 Billion by 2019 4Hospira Clinical Data Shows Proposed Biosimilar, Epoetin Hospira, Demonstrates Pharmacokinetic And Pharmacodynamic Equivalence Compared To Amgen's Epogen 2Hospira Clinical Data Shows Proposed Biosimilar, Epoetin Hospira, Demonstrates Pharmacokinetic And Pharmacodynamic Equivalence Compared To Amgen's Epogen 3Visceral Pain Pipeline Review H1 2015 Market Research Report 2Visceral Pain Pipeline Review H1 2015 Market Research Report 3Visceral Pain Pipeline Review H1 2015 Market Research Report 4
... announced today the closing of a $30 million Series B ... fund development of Elevation,s new aerosol therapy for patients living ... in the round, including Canaan Partners , TPG ... Venture Partners . In conjunction with this financing, Elevation has ...
... Calif., Jan. 4, 2012  MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) today ... J.P. Morgan Healthcare Conference on Wednesday, January 11, 2012 at ... webcast of the presentation will be available on the Investor ... A replay also will be available within 24 hours for ...
Cached Medicine Technology:Elevation Pharmaceuticals Completes $30 Million Series B Financing to Advance Aerosol COPD Therapy 2Elevation Pharmaceuticals Completes $30 Million Series B Financing to Advance Aerosol COPD Therapy 3
... gentle and effective surgical scrub with special ... is known to kill skin surface pathogens, ... protozoa and yeasts. It produces a rich ... pre-operative prepping, as well as for pre-and ...
... Aplicare two and four ounce ... meet the needs of procedural ... bottle itself has been custom ... match the cap perfectly. This ...
A patient skin prepping solution in a self-contained applicator combining two proven broad-spectrum antimicrobials: alcohol for fast kill and fast drying (3 minutes on skin), and an iodophor for pers...
Idophor PVP Scrub Winged Sponges...
Medicine Products: