Navigation Links
Pill box organizers increase HIV patients' adherence and improve viral suppression
Date:8/30/2007

Inexpensive pill box organizers are an easy, successful, and cost-effective tool to help patients take their medications as prescribed, according to a new study of low-income urban residents living with HIV infection by authors from the Berkeley School of Public Health and the University of California, San Francisco (UCSF). The research is published in the Oct. 1 issue of Clinical Infectious Diseases, now available online.

Clinicians and pharmacists can meaningfully improve treatment outcomes with simple and inexpensive strategies, such as pill box organizers, to help people organize how they take medication, said senior author David Bangsberg, MD, MPH, of UCSF.

Incomplete adherence to HIV therapy is the most common cause of incomplete viral suppression, drug resistance, disease progression, and death among people living with HIV/AIDS. The subjects of this study, who were recruited from homeless shelters, free food programs, and single-room occupancy hotels, are thought to be at elevated risk for poor adherence partly because of the high rates of substance abuse, untreated mental illness, and unstable housing.

Patients in this difficult-to-treat population were given inexpensive pill box organizers to use with their antiretroviral medications. Study organizers made a total of 3,170 unannounced visits every three to six weeks to the subjects places of residence and compared the number of pills remaining in the patients possession with the number that would be expected to remain if the patients were perfectly compliant with the treatment regimen.

Pill box organizers were associated with a 4 percent improvement in adherence, 0.12 log reduction in HIV viral load, and an estimated 11 percent reduction in the risk of progression to clinical AIDS. At only $5 per pill box, this intervention was highly cost-effective.

While this population has often been regarded as having difficulty with adherence, the authors write, adherence problems are by no means limited to patients with low socioeconomic status. Lead author Maya Petersen, PhD, from the Berkeley School of Public Health, adds, Incomplete adherence is a major problem that prevents people from realizing the full benefits of a wide range of treatments for chronic diseases, such as hypertension and diabetes mellitus. Thus, the findings of this study have the potential to inform a wide range of diseases, not just HIV.

It would be interesting to explore whether changes in packaging or delivery of antiretrovirals and other drugs could be used to reproduce the benefits of pill box organizer use. One model to consider is oral contraceptive therapy, which is routinely dispensed using labeled blister packs, a kind of pre-packaged version of a pill box. Antiretroviral regimens are generally more complicated, but a modification of this general model at either a pharmacy or manufacturer level might be possible, with wide-ranging patient benefits.


'/>"/>
Contact: Steve Baragona
sbaragona@idsociety.org
703-299-0412
Infectious Diseases Society of America
Source:Eurekalert

Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Mortality increased in Sporting enthusiasts!
3. Tattoos may significantly increase risk of hepatitis C infection
4. Increase in sugar...decrease in brain function!!!
5. Increase in tobacco deaths
6. Increased Heart Attack Risk From Celebrex,Vioxx
7. Human gene number increases
8. Stress response increases suicide risk
9. Sleep apnoea increases post-operative risks
10. Long travel increase pulmonary embolism
11. Antidepressants increase gastric bleeding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2017)... , ... September 20, 2017 , ... ... Maintain® methodology and industry-leading compliance software, The Guard®, has helped another long-time client ... (OCR) HIPAA audit and properly satisfy the law. , Thanks to the help ...
(Date:9/20/2017)... (PRWEB) , ... September 20, 2017 , ... ... digital and social campaign, “Humans With Vaginas.” The goal is to ignite conversation ... of non-toxic personal care products. The brand has declared September “Humans with Vaginas” ...
(Date:9/20/2017)... ... 20, 2017 , ... Medicare doesn’t have the authority to ... for their prescription drugs, according to a new comparison of drug plans by ... behalf, there’s no consistency in drug pricing among drug plans,” states TSCL’s Medicare ...
(Date:9/20/2017)... ... ... “The Trials I Face to Receive God’s Grace”: a mesmerizing take on ... to better one’s life through God. “The Trials I Face to Receive God’s Grace” ... places, found a love for writing. Green feels that expressing his feelings through prayer ...
(Date:9/20/2017)... ... ... Houston, Texas, investment firm CORDA Investment Management, LLC, believes in giving back. ... work and rolled up their sleeves to help with relief efforts. The team picked ... process of rebuilding. , CORDA founder Bonner C. Barnes notes that investment management firms ...
Breaking Medicine News(10 mins):
(Date:9/5/2017)... , Sept. 5, 2017  Just 18 months ... Insight is pleased to announce the appointment of three ... Tammy Wynne , Dominic Jones-Phillips and ... industry. Tammy ... team of market access writers. She has over ten ...
(Date:9/1/2017)... Ind. , Sept. 1, 2017  Explorers Like Us ... capture America,s greatest aural experiences — and deliver these experiences ... experience to help people feel and heal better. ... While nothing beats a ... and refresh your mind, Life Environments™ is the next best ...
(Date:8/29/2017)... Va. , Aug. 29, 2017 ivWatch, LLC, the ... peripheral IV infiltrations, announced it has been awarded an Innovative Technology ... company in the country. ... continuous monitoring device to aid in the early detection of peripheral ... The Innovative ...
Breaking Medicine Technology: