Navigation Links
Pill box organizers increase HIV patients' adherence and improve viral suppression
Date:8/30/2007

Inexpensive pill box organizers are an easy, successful, and cost-effective tool to help patients take their medications as prescribed, according to a new study of low-income urban residents living with HIV infection by authors from the Berkeley School of Public Health and the University of California, San Francisco (UCSF). The research is published in the Oct. 1 issue of Clinical Infectious Diseases, now available online.

Clinicians and pharmacists can meaningfully improve treatment outcomes with simple and inexpensive strategies, such as pill box organizers, to help people organize how they take medication, said senior author David Bangsberg, MD, MPH, of UCSF.

Incomplete adherence to HIV therapy is the most common cause of incomplete viral suppression, drug resistance, disease progression, and death among people living with HIV/AIDS. The subjects of this study, who were recruited from homeless shelters, free food programs, and single-room occupancy hotels, are thought to be at elevated risk for poor adherence partly because of the high rates of substance abuse, untreated mental illness, and unstable housing.

Patients in this difficult-to-treat population were given inexpensive pill box organizers to use with their antiretroviral medications. Study organizers made a total of 3,170 unannounced visits every three to six weeks to the subjects places of residence and compared the number of pills remaining in the patients possession with the number that would be expected to remain if the patients were perfectly compliant with the treatment regimen.

Pill box organizers were associated with a 4 percent improvement in adherence, 0.12 log reduction in HIV viral load, and an estimated 11 percent reduction in the risk of progression to clinical AIDS. At only $5 per pill box, this intervention was highly cost-effective.

While this population has often been regarded as having difficulty with adherence, the authors write, adherence problems are by no means limited to patients with low socioeconomic status. Lead author Maya Petersen, PhD, from the Berkeley School of Public Health, adds, Incomplete adherence is a major problem that prevents people from realizing the full benefits of a wide range of treatments for chronic diseases, such as hypertension and diabetes mellitus. Thus, the findings of this study have the potential to inform a wide range of diseases, not just HIV.

It would be interesting to explore whether changes in packaging or delivery of antiretrovirals and other drugs could be used to reproduce the benefits of pill box organizer use. One model to consider is oral contraceptive therapy, which is routinely dispensed using labeled blister packs, a kind of pre-packaged version of a pill box. Antiretroviral regimens are generally more complicated, but a modification of this general model at either a pharmacy or manufacturer level might be possible, with wide-ranging patient benefits.


'/>"/>
Contact: Steve Baragona
sbaragona@idsociety.org
703-299-0412
Infectious Diseases Society of America
Source:Eurekalert

Related medicine news :

1. Use of Cellular Phones associated with Increased risk of Brain Tumors
2. Mortality increased in Sporting enthusiasts!
3. Tattoos may significantly increase risk of hepatitis C infection
4. Increase in sugar...decrease in brain function!!!
5. Increase in tobacco deaths
6. Increased Heart Attack Risk From Celebrex,Vioxx
7. Human gene number increases
8. Stress response increases suicide risk
9. Sleep apnoea increases post-operative risks
10. Long travel increase pulmonary embolism
11. Antidepressants increase gastric bleeding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/26/2017)... ... ... Capillus, LLC has announced the redesign of their FDA-cleared low-level laser (light) therapy ... more comfortable, adaptable fit and is available for purchase immediately. , Carlos Piña, ... caps intended to improve both user experience and hair regrowth. , “Our customers ...
(Date:7/26/2017)... , ... July 26, 2017 , ... It may be ... often not accessible to people in the third world. Diseases that many developed countries ... poor children who don't have access to vaccines. , On an upcoming segment of ...
(Date:7/26/2017)... ... July 26, 2017 , ... Team Type 1 Foundation, a nonprofit organization pursuing ... by diabetes, is excited to announce the 106 college athletes with type 1 diabetes ... in 2005, the Team Type 1 Foundation has bestowed a total of 271 college ...
(Date:7/26/2017)... (PRWEB) , ... July 26, 2017 , ... The Amnesty ... p.m. at Charles Johnson Park at 3313 Bernstein Park Drive in Monroe (adjacent to ... Rally is to help reduce gun violence throughout Monroe. Citizens can turn in ...
(Date:7/25/2017)... ... 25, 2017 , ... Summers in Palm Springs sizzle, but there are ways ... gourmet ice cream, sparkling pools, and mile-high fun. , At Arrive's Ice Cream and ... other must-have knick knacks. Ice cream and sorbet flavors rotate, but the classics are ...
Breaking Medicine News(10 mins):
(Date:7/11/2017)...  Sysmex America, Inc., a leading provider of ... well as middleware information systems technology, today announced ... assurance easier and more risk free than manual ... the innovation that it delivers to the laboratory. ... processes to a new level with automated, continuous ...
(Date:7/11/2017)... 2017 Oramed Pharmaceuticals Inc. (NASDAQ: ... focused on the development of oral drug delivery systems, ... (FDA) has agreed to schedule an End-of-Phase II meeting ... of its oral insulin capsule ORMD-0801 in the treatment ... primary and secondary endpoints by indicating a statistically significant ...
(Date:7/10/2017)... 2017 The Institute for In Vitro Sciences ... recipient of a VITROCELL® inhalation exposure system thanks to ... The device, which is designed to replace animals in ... cells to airborne test materials in an environment that ... system for testing combustible tobacco products, as well as ...
Breaking Medicine Technology: