Navigation Links
Pill Equals Injection in Preventing Clots After Hip Replacement
Date:9/14/2007

Study found no difference between the two protective treatments

FRIDAY, Sept. 14 (HealthDay News) -- In a head-to-head trial, Swedish researchers found that a pill called dabigatran etexilate (DE) is just as effective as an injected drug, enoxaparin, in reducing the risk of blood clots after total hip replacement surgery.

As reported in this week's issue of The Lancet, the study included almost 3,500 hip replacement patients who received either oral DE at 220 milligrams daily, DE at 150 milligrams daily, or an injection of enoxaparin at 40 milligrams once daily, for 28 to 35 days.

Blood clots or death from all causes occurred in 53 of 880 (6 percent) of patients on 220 milligrams DE, in 75 of 874 (8.6 percent) of patients on 150 milligrams DE, and in 60 of 897 (6.7 percent) of patients in the enoxaparin group.

The researchers found no significant differences in bleeding rates, frequency of coronary events, or increases in liver enzyme concentrations between the three groups of patients.

There were also no differences between the groups in terms of "reducing the risk of total venous thromboembolism, and all-cause mortality after total hip replacement," wrote the researchers from Sahlgrenska University Hospital in Gothenburg.

The study was funded by Boehringer Ingelheim, the company that makes DE.

In an accompanying editorial, Dr. John Norrie of the Centre for Healthcare Randomised Trials at the University of Aberdeen in Scotland, also notes that the study did have methodological flaws, linked to missing data.

More information

The MedlinePlus Medical Encyclopedia has more about blood clots.



-- Robert Preidt



SOURCE: The Lancet, news release, Sept. 13, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Calcium and Protein Equals Strong Bones
2. Good Oral Health Equals Good Health for Your Heart
3. Cement injections linked to osteoporosis
4. Sharing injection equipment spreads Hepatitis C
5. Toxin injections support stroke associated spasticity
6. Injection supports Heart Devices
7. Abstinence From Alcohol With The Help Of An Injection
8. Exubera could mean the end of an insulin injection era for diabetics
9. Unsafe Injections and Unclean Hand hygiene major cause of hospital infections in India
10. Leptin Injections Maintain Loss In Body Weight
11. FDA Approves Novel Creation of Imitrex? Injection for Migraine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2017)... ... ... Month and the focus is on prostate cancer. Second only to skin cancer, prostate ... common cause of cancer related death today; lung cancer remains in the number one spot. ... during his lifetime. Those at highest risk are men who have a family ...
(Date:6/24/2017)... ... ... Doorknobs are for convenience, deadbolts are for security. , There are many ... an alarm system installed. But unless there is a working deadbolt lock that is ... Premier Locksmith in Killeen, TX says: “In the majority of home burglaries, intruders use ...
(Date:6/23/2017)... ... June 24, 2017 , ... Studies show evidence that carotenoids and antioxidants derived ... loss in these patients. , But how often do ophthalmologists and optometrists in Sweden ... at risk of or with early symptoms of AMD? A study published recently ...
(Date:6/23/2017)... ... ... Goodcents Deli Fresh Subs today announced the opening of a new restaurant ... Topeka, Kan. 66604 (near 21st and Gage). It is owned and operated by long-time ... in the Topeka and Bonner Springs, Kan. area. , “Goodcents has such a ...
(Date:6/23/2017)... ... June 23, 2017 , ... MD Now Urgent ... is MD Now’s 28th facility overall and marks the urgent care center's eighth location ... mile North of The Falls shopping mall. The new clinic offers a wide array ...
Breaking Medicine News(10 mins):
(Date:6/7/2017)... 7, 2017  Novavax, Inc., (Nasdaq: NVAX ) ... 2 trials of its RSV F protein recombinant nanoparticle vaccine ... have been published in the journal Vaccine ... in prior scientific conferences). The Company previously announced top ... is developing the RSV F Vaccine with the goal of ...
(Date:6/2/2017)... , June 2, 2017  NxStage Medical, Inc. (Nasdaq:  NXTM), a ... today announced new findings demonstrating positive biochemical outcomes related ... System One™. The data will be presented at the ... Madrid, Spain . The ... Home Dialysis Network in Europe ...
(Date:5/29/2017)... -- Cellect Biotechnology Ltd. (NASDAQ: APOP ; TASE: APOP), ... selection of stem cells, today provided a corporate update ... March 31 st , 2017. "We ... quarter of 2017," said Dr. Shai Yarkoni, Chief Executive ... of the first blood cancer patient in the recently ...
Breaking Medicine Technology: