Navigation Links
Pigs Yield Clues to Cystic Fibrosis-Related Lung Disease
Date:4/28/2010

Infection appears to precede inflammation, researchers find

WEDNESDAY, April 28 (HealthDay News) -- Researchers say they have answered a long-standing question regarding lung disease caused by cystic fibrosis: Which comes first, infection or inflammation?

"Using our model, we are beginning to answer that question, and it looks like infection does precede inflammation," study author Dr. David Stoltz, an assistant professor of internal medicine at the University of Iowa, said in a news release from the school. "The importance of that finding is that it could dictate what types of therapy we might use. Knowing that infection is first suggests that if we can prevent or fight infection, then that might delay or prevent the lung disease in people with CF."

Most of the deaths and disability in people with CF result from lung disease.

The findings also appear to suggest that lung infections in children with cystic fibrosis should be treated early and aggressively, Stoltz said.

The researchers reached their conclusions by studying pigs with a genetic mutation that causes cystic fibrosis.

"This is a really great example where the pig serves as a model for what happens in the human, and the pig reacts to this disease in nearly the same way," study co-author Randall Prather, distinguished professor of reproductive biotechnology at the University of Missouri, said in the news release. "In contrast, when you use mice, they don't get the lung disease that is common in patients with cystic fibrosis."

The study was published online April 28 in the journal Science Translational Medicine.

More information

For more about cystic fibrosis, see the U.S. National Library of Medicine.



-- Randy Dotinga




'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. LSUHSC research yields promising stroke treatment
2. Compulsive Dogs Yield Clues to Human OCD, Autism
3. Battlefield camaraderie yields long-term dividends for veterans, study finds
4. Why do physicians order costly CTs? Ultrasound yields better diagnosis, safer, less costly
5. Gene Sequencing Yields Picture of Human Gut
6. HealthSouth To Present at Barclays Capital 2010 High Yield Bond and Syndicated Loan Conference
7. Abbreviated Trials Yield Misleading Results: Study
8. H1N1 Virus Yields Up More Secrets
9. Safety and diagnosis yield of colonoscopy in Hong Kong Chinese children
10. Glued graft for Pterygium Yield Better Cosmetic Results
11. Review Spotlights Clues to Serious Childhood Infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... ... June 30, 2015 , ... The American Lung Association in California ... event in San Diego. Speakers and clean air advocates included San Diego County Supervisor ... of Kindred Hospital, and Daniel Sullivan, founder and president of Sullivan Solar Power. ...
(Date:6/30/2015)... ... June 30, 2015 , ... ... today that they have been awarded the exclusive billing agreements with Jackson Radiology ... of billing services encompassing their proprietary suite of billing process software functionality called ...
(Date:6/30/2015)... ... June 30, 2015 , ... Broadway by the Sea posted its newest ... family member testimonials. Medicare rated the care center as a five-star location based on ... to give future patients a firsthand look at the facility’s satisfied residents. , ...
(Date:6/30/2015)... ... June 30, 2015 , ... Family ... of Colorado's Education Symposium on November 9, 2015 at the Hyatt Regency Denver ... a conversation with Kim and Ashley Campbell, the wife and daughter of singer ...
(Date:6/30/2015)... ... June 30, 2015 , ... Rocky Mountain Oils, a leading non-MLM ... team and added a new CEO, Mr. Darold Francis. The changes will help enhance ... essential oils that customers have come to know and respect for over eight years. ...
Breaking Medicine News(10 mins):Health News:Local Dignitaries Gather to Announce San Diego’s Clean Air Challenge 2Health News:Local Dignitaries Gather to Announce San Diego’s Clean Air Challenge 3Health News:ADVOCATE Wins Billing Agreements with Jackson Radiology Associates 2Health News:Broadway by the Sea Video Promotes Top Quality Service 2Health News:Family of Singer Glen Campbell to Discuss Living with Dementia at the Alzheimer's Association of Colorado's 26th Annual Education Symposium 2Health News:Rocky Mountain Oils Adds New CEO, Announces Relocation of Operations to Orem, Utah 2
... 10, 2010) - The Massachusetts Eye and Ear ... awarded a grant renewal from the National Institutes of ... support first-rate clinician scientists to promote translational and clinical ... NEI renewed a five-year K12 grant to Mass. Eye ...
... 135th Commencement ... ... at the 135th Commencement ceremony for Meharry Medical College on May 22. Commencement ... open at 11:30 a.m., , , , ,Congressman Clyburn is the Majority Whip in the U.S. ...
... nearly tripled in one year, study finds , MONDAY, May ... is gaining popularity in western countries, and those most likely ... their parents, a new study finds. , Young adults in ... to 20-year-old, English-speaking males who live away from their parents ...
... better supportive care helped push the survival for children ... years after diagnosis, according to new research led by ... the medical journal The Lancet Oncology . The ... than previously reported U.S. rates and is similar to ...
... localized cancer, more conservative treatment may be warranted, study finds ... does not seem to extend the life of elderly people ... finds. , Instead, it suggests, people with such cancer should ... their kidneys. , Kidney cancer cases have increased over ...
... ... À la Carte and Packaged Options Including Publishing, Distribution to Major ... and Specialized Radio Media Tour for Sell-Through,“As the publishing industry has ... authors are opting for self-publishing, but they don’t have the marketing ...
Cached Medicine News:Health News:Mass. Eye and Ear receives NEI grant renewal for 'growing' clinical/scientists 2Health News:Congressman James E. Clyburn to Give Meharry Medical College Commencement Address 2Health News:Congressman James E. Clyburn to Give Meharry Medical College Commencement Address 3Health News:Hookahs an Unhealthy Hit Among Privileged Young Adults 2Health News:Hookahs an Unhealthy Hit Among Privileged Young Adults 3Health News:Smarter use of existing treatment helps dramatically boost survival of young AML patients 2Health News:Bookstomarketnow.Com Launches To Provide Publishing, Distribution & Marketing Solutions For The Self-Publishing Author 2Health News:Bookstomarketnow.Com Launches To Provide Publishing, Distribution & Marketing Solutions For The Self-Publishing Author 3Health News:Bookstomarketnow.Com Launches To Provide Publishing, Distribution & Marketing Solutions For The Self-Publishing Author 4Health News:Bookstomarketnow.Com Launches To Provide Publishing, Distribution & Marketing Solutions For The Self-Publishing Author 5Health News:Bookstomarketnow.Com Launches To Provide Publishing, Distribution & Marketing Solutions For The Self-Publishing Author 6
(Date:6/30/2015)... , June 30, 2015 Zynerba Pharmaceuticals, Inc. ... Form S-1 with the U.S. Securities and Exchange Commission (SEC) ... stock. The number of shares to be offered and the ... Jefferies LLC and Piper Jaffray & ... and Canaccord Genuity Inc. and Oppenheimer & Co. Inc. will ...
(Date:6/30/2015)... SACRAMENTO, Calif. , June 30, 2015 A ... estimate California,s exposure to high-priced Hepatitis ... even if only 5 percent of Californians infected with Hepatitis ... at the costly impact of new Hepatitis C treatments on ... agencies grapple with hefty price tags for drugs like Gilead ...
(Date:6/30/2015)... TAMPA, Fla. , June 30, 2015  Today, ... four winners of the 2015 National Mobility Awareness Month ... with 914 Local Hero online entries that received 1.3 ... are Chrysler , Toyota Mobility , and ... by BraunAbility and Vantage Mobility International ...
Breaking Medicine Technology:Zynerba Files Registration Statement for Proposed Initial Public Offering of Common Stock 2New Analysis Reveals High-Priced Hepatitis C Drugs Could Have Costly Impact on State 2New Analysis Reveals High-Priced Hepatitis C Drugs Could Have Costly Impact on State 3New Analysis Reveals High-Priced Hepatitis C Drugs Could Have Costly Impact on State 4NMEDA Announces National Contest Winners 2NMEDA Announces National Contest Winners 3
... 4, 2012 Omthera Pharmaceuticals, Inc., a privately-held emerging ... and Chief Executive Officer, will present at the 30th ... 2012 at 8:30am PST at The Westin St. Francis ... Pharmaceuticals, Inc. Founded in 2008, Omthera Pharmaceuticals, Inc. ...
... DES MOINES, Iowa, Jan. 4, 2012  Pharmaceutical marketers who ... spending to maximize ROI have limitless questions. ... optimization methodology developed by RMi with a patent-pending ... hoc reporting to help brand leaders find answers. ...
Cached Medicine Technology:Omthera Pharmaceuticals, Inc. to Present at the 30th Annual J.P. Morgan Healthcare Conference 2RMi Introduces SyntheSight™ Pharma Multi-Channel Optimization Suite 2RMi Introduces SyntheSight™ Pharma Multi-Channel Optimization Suite 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: