Navigation Links
Pigs Yield Clues to Cystic Fibrosis-Related Lung Disease
Date:4/28/2010

Infection appears to precede inflammation, researchers find

WEDNESDAY, April 28 (HealthDay News) -- Researchers say they have answered a long-standing question regarding lung disease caused by cystic fibrosis: Which comes first, infection or inflammation?

"Using our model, we are beginning to answer that question, and it looks like infection does precede inflammation," study author Dr. David Stoltz, an assistant professor of internal medicine at the University of Iowa, said in a news release from the school. "The importance of that finding is that it could dictate what types of therapy we might use. Knowing that infection is first suggests that if we can prevent or fight infection, then that might delay or prevent the lung disease in people with CF."

Most of the deaths and disability in people with CF result from lung disease.

The findings also appear to suggest that lung infections in children with cystic fibrosis should be treated early and aggressively, Stoltz said.

The researchers reached their conclusions by studying pigs with a genetic mutation that causes cystic fibrosis.

"This is a really great example where the pig serves as a model for what happens in the human, and the pig reacts to this disease in nearly the same way," study co-author Randall Prather, distinguished professor of reproductive biotechnology at the University of Missouri, said in the news release. "In contrast, when you use mice, they don't get the lung disease that is common in patients with cystic fibrosis."

The study was published online April 28 in the journal Science Translational Medicine.

More information

For more about cystic fibrosis, see the U.S. National Library of Medicine.



-- Randy Dotinga



SOURCE: University of Iowa, news release, April 28, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. LSUHSC research yields promising stroke treatment
2. Compulsive Dogs Yield Clues to Human OCD, Autism
3. Battlefield camaraderie yields long-term dividends for veterans, study finds
4. Why do physicians order costly CTs? Ultrasound yields better diagnosis, safer, less costly
5. Gene Sequencing Yields Picture of Human Gut
6. HealthSouth To Present at Barclays Capital 2010 High Yield Bond and Syndicated Loan Conference
7. Abbreviated Trials Yield Misleading Results: Study
8. H1N1 Virus Yields Up More Secrets
9. Safety and diagnosis yield of colonoscopy in Hong Kong Chinese children
10. Glued graft for Pterygium Yield Better Cosmetic Results
11. Review Spotlights Clues to Serious Childhood Infection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/20/2017)... ... February 20, 2017 , ... Scrubbing in for his first ... Dr. Christopher Pezzi remembers the excitement of the surgeon training him. , “He was ... to do this? Don’t tell anyone, but I would do it for free,’” Dr. ...
(Date:2/20/2017)... ... 2017 , ... Today, Biscom , the leader in ... IoT device from Biscom designed to deliver confidential patient information securely and quickly, ... HIMSS17 and will be conducting demonstrations at Booth #374. , With ...
(Date:2/20/2017)... , ... February 20, 2017 , ... Johns Hopkins All ... education building. A topping out ceremony on Friday marked the halfway point of construction ... to open in Fall 2018, will serve as a center for innovation aimed at ...
(Date:2/19/2017)... (PRWEB) , ... February 19, 2017 , ... Braun Industries ... JEMS Conference & Exposition, the event will take place February 23-25, 2017 at the ... will be in Booth #909 with three new ambulances on display. ...
(Date:2/18/2017)... ... February 17, 2017 , ... Focused start-ups, not traditional health ... according to the recent NEJM Catalyst Insights Report on the New Marketplace. ... Insights Council, a qualified group of U.S. executives, clinical leaders, and clinicians at ...
Breaking Medicine News(10 mins):
(Date:2/20/2017)... ORLANDO, Fla. , Feb. 20, 2017 /PRNewswire/ ... are helping physicians diagnose and treat patients with ... will provide wireless connectivity for ZywiePro, Zywie,s cardiac ... AT&T Control Center . AT&T ... accessible monitoring for those with the disease. The ...
(Date:2/20/2017)... , Feb 20, 2017 Research and ... Devices Global Market -Forecast to 2022" report to their ... ... rise in aging population, rising adoption of tension free repair ... the growth of hernia repair devices global market. However, Inconsistent ...
(Date:2/20/2017)... 2017 The global  animal ... billion by 2025, according to a new study ... driven by technological advancements in veterinary care, which ... the market. For instance, MediLabSecure, a laboratory network ... emerging viruses and pathogens in 19 countries in ...
Breaking Medicine Technology: