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Pier Paolo Pandolfi, M.D., Ph.D., to receive Pezcoller-AACR International Award for Cancer Research
Date:1/12/2011

acute promyelocytic leukemia [APL], and, today, this unique expertise in mouse-model engineering is helping to speed the clinical testing of new personalized cancer therapies."

Among his many accomplishments, Pandolfi's prolific laboratory has characterized the function of oncoproteins and genes involved in the chromosomal translocations of APL, as well as of major tumor suppressors such as PTEN and p53, and novel proto-oncogenes, such as POKEMON. More recently, Pandolfi's laboratory challenged a central dogma of molecular biology with the discovery of a novel and critically important new role for messenger RNA that includes previously unrecognized biological functions for both coding and noncoding mRNA.

"I'm extremely honored to receive the Pezcoller award," says Pandolfi. "This is a tremendously exciting time I would even say revolutionary for cancer research and I'm thrilled to be a part of it. As we now clearly recognize, 'cancer' is not a single disease, but is made up of many, many different mutations. While this provides us with unprecedented opportunities for developing personalized treatments, our ultimate goal is to understand and cure cancer, and this award gives us further motivation to achieve this goal as we continue to fight relentlessly for the sake of our patients."

A native of Rome, Pandolfi received his MD in 1989 and PhD in 1995, both from the University of Perugia, Italy. He completed post-graduate work at the Royal Postgraduate Medical School, University of London, before joining the faculty of Memorial Sloan-Kettering Cancer Center and the Weill Graduate School of Medical Sciences at Cornell University in 1994.

Pandolfi is the recipient of numerous awards and honors, including a National Institutes of Health/National Cancer Institute MERIT Award; the Leukemia and Lymphoma Society of America Stohlman Scholar Award; the Weizmann Institute of Science: Sergio Lombroso Prize for Cancer Research; the William a
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Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
Source:Eurekalert

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