Navigation Links
Physicians Still Hopeful About Desmoteplase for the Treatment of Acute Ischemic Stroke Despite Negative Results
Date:1/30/2008

Surveyed Neurologists Identify a Six-Hour Treatment Window as Area of Greatest Dissatisfaction, According to a New Report from Decision Resources

WALTHAM, Mass., Jan. 30 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that physicians are still hopeful about Paion/Lundbeck's desmoteplase despite recent negative results. Although desmoteplase demonstrated efficacy on a stringent composite measure of overall outcome when delivered within nine hours of stroke onset in the DIAS-1 trial, the drug failed to meet the same efficacy outcome in the larger DIAS-2 Phase III clinical trial. Experts interviewed by Decision Resources suggest that issues of clinical trial design, rather than the action of the drug, may have led to the failure of desmoteplase in the DIAS-2 trial. Despite these findings, surveyed neurologists indicate that they would prescribe the drug to 10% of their diagnosed acute ischemic stroke patients.

According to the new report entitled: Acute Ischemic Stroke: Despite Negative Results, Physicians Still Hopeful about Desmoteplase, surveyed neurologists continue to identify a six-hour treatment window as the area of greatest dissatisfaction. The development of a reperfusion agent with a wider time window would represent an important near-term solution by increasing the number of acute ischemic stroke patients who receive treatment.

"Between the two emerging therapies included in this study, desmoteplase appears to have the potential to meet many of the safety and delivery criteria of our 'Minimal Acceptable' target product profile," said Sami Fam, Ph.D., analyst at Decision Resources. "Surveyed neurologists would treat 10% of their patients with such an agent -- that is three times more than those who are getting treated currently with rt-PA. The arrival of such a reperfusion agent would signal a new dawn for the treatment of acute ischemic stroke, which is miserably undertreated today."

About Acute Ischemic Stroke: Despite Negative Results, Physicians Still Hopeful about Desmoteplase

Acute Ischemic Stroke: Despite Negative Results, Physicians Still Hopeful about Desmoteplase is a DecisionBase 2008 report from Decision Resources. DecisionBase 2008 combines market forecasts with clinical and commercial end points to assess market share projections in 35 indications. These outputs are driven by quantitative and qualitative primary research. DecisionBase 2008 provides detailed market share, patient share, and price-per-day projections for emerging drugs in development. The market share projections are based on prescriber surveys that compare physicians' expectations of a potential target product profile with an emerging product profile of the leading drugs in development.

The report can be purchased by contacting Decision Resources. Members of the media may request an interview with an analyst.

About Decision Resources

Decision Resources, Inc. (http://www.decisionresources.com) is a world leader in market research publications, advisory services, and consulting designed to help clients shape strategy, allocate resources, and master their chosen markets. Decision Resources is a Decision Resources, Inc. company.

All company, brand, or product names contained in this document may be trademarks or registered trademarks of their respective holders.

For more information, contact:

Elizabeth Marshall

Decision Resources, Inc.

781-296-2563

emarshall@dresources.com


'/>"/>
SOURCE Decision Resources
Copyright©2008 PR Newswire.
All rights reserved

Related medicine news :

1. Onmark Launches Integrated Quality(TM) Program to Help Physicians Succeed With National Quality Initiatives
2. Elseviers WiserWiki allows physicians to update evidence-based medical information
3. Elseviers "WiserWiki" Allows Physicians to Update Evidence-Based Medical Information With Experience-Based Practice Insights
4. AAFP Statement - Family Physicians to President Bush: Call for Improved Health Access is Only One Step to Comprehensive Reform
5. Report: Too Few Physicians, Nurses to Implement Presidential Candidates Health Reform Plans
6. Struggling Medical Delivery System Impacts Hospitals and Physicians Hardest
7. Phony Physicians Committee Suing Restaurants is Animal-Rights Trojan Horse, says CCF
8. Wisconsin Physicians Service Insurance Corporation Files Suit Against Aurora Health Care and HealthEOS
9. Physicians Want to Learn From Medical Mistakes But Say Current Error-Reporting Systems are Inadequate
10. Childrens Hospital physicians publish review of transplant issues in patients with biliary atresia
11. American College of Physicians receives grant to study cost of patient-centered medical home
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... ... working together to expand dental health services to the developmentally disabled in the ... Care Dental’s operations to a new facility at 71-949 Highway 111, Suite 100-B, ...
(Date:2/10/2016)... ... February 10, 2016 , ... InDemand Interpreting , ... recently partnered with Heart City Health Center to improve access to ... Heart City Health Center has provided the Elkhart community with access to high ...
(Date:2/10/2016)... ... February 10, 2016 , ... ... charity program created to assist the local community. Pledging to select a new ... nonprofit organizations in the area. Their goal is to bring community awareness to ...
(Date:2/10/2016)... ... February 10, 2016 , ... Dr. ... office is now offering a variety of comprehensive procedures for facial enhancement. The ... facial volume restoration, lip enhancement and nasal reshaping. , As a result, ...
(Date:2/10/2016)... ... February 10, 2016 , ... Intalere’s 2016 Executive Forum, ... 200 of the country’s top healthcare executives to share insights on transformational strategies ... the Forum is the provider-centric perspective, experience, expertise and strategy shared by the ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... -- Urologix, the market leader for in-office minimally invasive ... (BPH), announces new private ownership and is operating as ... industry veteran of more than 20 years, has been ... Plymouth, Minn. The company,s two ... RF Therapy, will continue to be broadly available and ...
(Date:2/10/2016)... Feb. 10, 2016  Rich Pharmaceuticals, Inc. (OTC Markets: ... 1-for-100 reverse split of its issued and outstanding shares ... on Thursday, February 11, 2016. The Company,s common stock ... number 76303T308 and temporary ticker symbol "RCHAD". After 20 ... the ticker symbol (RCHA).  --> ...
(Date:2/10/2016)... 10, 2016  Oxis International Inc. (OTC/QB: OXIS) announced ... described as a "clinical trial triumph" after one of ... complete cancer remission. Daniel Vallera , ... Cancer Center. --> Daniel Vallera , ... Cancer Center. --> An article on ...
Breaking Medicine Technology: