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Physical fitness level affects kidney function in type 2 diabetes
Date:6/23/2014

CHICAGO, IL Adults with Type 2 diabetes who improve their physical fitness lower their chances of getting chronic kidney disease (CKD), and if they already have kidney damage, they can improve their kidney function. These findings come from a new study presented Monday at the joint meeting in Chicago of the International Society of Endocrinology and the Endocrine Society: ICE/ENDO 2014.

Health care providers have long known that exercise has a beneficial impact on overall health and wellness in both the general public and people with Type 2 diabetes. This study, though, demonstrated the benefit of improved physical fitness on a common complication of diabetesCKDwhich in some people can lead to kidney failure and death.

"It is essential for individuals with Type 2 diabetes to improve their physical fitness because it can improve kidney deterioration and reduce mortality," said the study's lead investigator, Shruti Gandhi, MD, an endocrinologist at Washington DC Veterans Affairs (VA) Medical Center.

The study had two parts. In the first part, the researchers looked at data for 2,007 patients (primarily men) with Type 2 diabetes who had normal kidney function when they completed an exercise stress test at the VA hospital in Washington, D.C. They had an average age of 61.Their fitness level, or peak exercise capacity, was scored using the number of metabolic equivalents (METs) they achieved during the test, which increases with exercise intensity. Patients who achieved less than 5.5 METs were classified as least fit; 5.5 to 7.5 METS, as low fit; 7.6 to 9.5 METS, as moderately fit; and more than 9.5 METs, as highly fit.

During the follow-up period, which averaged seven years, 572 patients developed CKD or died of any cause. Because there were not enough data for separate analysis, the researchers combined cases of CKD and deaths, Gandhi explained.

Their data analysis showed that the combined death rate and progression
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Contact: Aaron Lohr
alohr@endocrine.org
202-971-3654
The Endocrine Society
Source:Eurekalert

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