Navigation Links
Physical activity reduces the effect of the obesity gene in adolescents
Date:5/4/2010

The FTO gene is obesity's main ally. Several studies are now attempting to reveal the factors that play a key role in fighting against it. A new study led by Spanish researchers shows that a physically active lifestyle during adolescence can reduce the effect of a mutation in this gene which predisposes someone to becoming overweight or obese.

Among the genes correlated to obesity, the FTO (or fat mass gene) is one of the genes responsible for the accumulation of fat in humans. "Each copy of the mutation of this gene is associated with an increase of 3.3 lbs. This means that people who have two copies can weigh 6.6 lbs more than those who have no copies", Jonatan Ruiz, leader of the study and researcher at the Karolinska Institute in Stockholm (Sweden), explains to SINC.

The authors based their research on data collected in the European study HELENA, led by the University of Zaragoza, which analyses the effect of the FTO gene on weight and body fat in adolescents from nine European countries, among them, Spain. Furthermore, the new work records if the effect of this gene is independent of the level of physical activity performed by adolescents.

The results, published in the journal Archives of Pediatrics & Adolescent Medicine, reveal that in Europe, 37% of the assessed adolescents did not have any copy of the mutation, 47% had one copy and 16% had two. The research project appears among the five finalists for the Award for Scientific Excellence organised by the International Association for the Study of Obesity (IASO).

"Although the genetic mutation is linked to a higher rate of body mass, fat, and waist circumference, what is interesting is that its effect practically disappears among adolescents who perform the daily recommended amount of physical activity", highlights the expert.

It's not all in the genes

For this reason, "performing the recommended amount of physical activity can counteract a genetic predisposition to become overweight or obese", stresses Ruiz. The study also challenges "the widespread belief and fear that genetics determine the risk of developing a disease and that we can't do anything about this".

In this regard the work demonstrates that modifying lifestyle can cancel the negative effect some genetic mutations have on health. "For young people, one hour of sport per day is enough to reduce the potential risk of this genetic mutation", he adds. However, the study observed that almost 60% of European adolescents do not comply with these recommendations.

The fat mass gene and the Mediterranean diet

Obesity is a disease influenced by both genetic factors and lifestyle (nutrition and physical activity). Another research project, led by Amelia Mart from the University of Navarra, analyses the effects of the rs9939609 variant of the FTO gene on weight change, as well as its modification through consuming a Mediterranean diet.

This study, published recently by the International Journal of Obesity, was performed on 776 subjects with high cardiovascular risk, aged between 55 and 80 years old. The samples were taken from the Predimed trial and the results revealed that people with the rs9939609 mutation had a higher body weight. They also confirmed that the Mediterranean diet offers protection against the adiposity associated with this mutation.


'/>"/>

Contact: SINC
info@plataformasinc.es
34-914-251-820
FECYT - Spanish Foundation for Science and Technology
Source:Eurekalert  

Related medicine news :

1. Physical Therapist, Money Launderer and Patient Recruiter Plead Guilty in Connection With Multiple Detroit Health Care Fraud Schemes
2. State Health, Education Leaders Applaud Luzerne County School for Boosting Physical Activity Among Students
3. New Book Reveals Eye-Opening Look Inside Physical and Spiritual Well-Being
4. Physical Therapist Pleads Guilty in Connection with Detroit Home Health Care Fraud Scheme
5. State Health, Education Leaders Hail Avonworth Middle School in Allegheny County for Boosting Physical Activity Among Students
6. Reproductive coercion often is accompanied by physical or sexual violence, study finds
7. North American Seminars Inc. Opens Its 2010 Physical Therapy Continuing Medical Education Course Sponsorship Program
8. Physical Activity May Prolong Survival After Colon Cancer
9. Mastery of physical goals lessens disease-related depression and fatigue
10. IHRSA's Campaign for a Healthier America Calls on All Americans to Curtail Health Care Costs in 2010 by Becoming Physically Active
11. Almost two-thirds of pregnant women believe they are regularly exposed to physical risk at work
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Physical activity reduces the effect of the obesity gene in adolescents
(Date:2/23/2017)... (PRWEB) , ... February 23, 2017 , ... Dr. David ... in Henderson, NV 89052. Dr. Mahon was named a 2017 Top Patient Rated ... is an online directory that recognizes local physicians and dentists who have earned ...
(Date:2/23/2017)... (PRWEB) , ... February 23, 2017 , ... ... Phoenix, announced today that it will soon begin franchising throughout the U.S. starting ... mission to help bring the practice of meditation mainstream. Current Meditation will be ...
(Date:2/23/2017)... ... (PRWEB) February 23, 2017 ... nation to come together to combine its favorite springtime pastime ... favorite fruit – apples! To celebrate National Nutrition Month, the ... “Apple Madness” bracket tournament – a five-week, five-round online competition ...
(Date:2/23/2017)... ... , ... Curemark, LLC announced today that the Blüm Study, a Phase 3 ... with Autism, is now enrolling at three new sites. These new sites are in ... , “There are currently no approved drugs that address the core symptoms of autism,” ...
(Date:2/23/2017)... ... February 23, 2017 , ... Carlos Gutierrez has lived ... continued to spiritually evolve, which is the purpose of everyone in this universe. As ... ” (published by Balboa Press) attempts to guide readers to expand one’s spiritual life. ...
Breaking Medicine News(10 mins):
(Date:2/23/2017)... Feb. 23, 2017  As National Nutrition Month ... the Company is helping people live healthier lives ... prescription savings programs in all 50 states including:  ... Program  and  California Prescription Assistance Program . ... Columbia University for nutritious eating habits: ...
(Date:2/23/2017)... February 23, 2017 The top ... are GE Healthcare, Koninklijke Philips N.V., and Schiller. Collectively, ... the global market in 2015. Strong product portfolio and ... assessed to be aiding these players remain leaders in ... the players in the global market are likely to ...
(Date:2/23/2017)... DUBLIN , Feb 23, 2017 Research ... Prosthetic Devices Market Analysis & Trends - Industry Forecast to 2025" ... ... to grow at a CAGR of around 9.2% over the next ... industry report analyzes the market estimates and forecasts for all the ...
Breaking Medicine Technology: