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Physical activity does not protect against in situ breast cancer
Date:2/28/2013

A European study published in the 'Cancer Epidemiology, Biomarkers & Prevention' journal has analysed the association between physical activities and in situ or non-invasive breast cancer, or, in other words, cancer that has not yet invaded cells within or outside of the breast.

Headed by researchers from ten European countries including Spain, the work carried out under the framework of the European Prospective Investigation into Cancer and Nutrition (EPIC) concludes that physical activity has no relation with the risk of developing this type of non-invasive cancer.

After more than eleven years following a European cohort of 283,927 women, 1,059 of whom had in situ cancer, the authors also found no association depending on exercise type.

In addition, the results did not vary between women of pre- and post-menopausal age or between obese and non-obese women. The same does not occur in the case of invasive cancer, where epidemiological studies have demonstrated that this factor is associated with a lesser risk.

"The aetiology (cause) of in situ breast cancer could be different to that of invasive breast cancer, or rather physical activity has a protective effect only in later stages of the carcinogenesis process. This would explain why no association has been found in non-invasive breast cancer," upholds Mara Jos Snchez Prez, Director of the Granada Cancer Registry and one of the authors of the study.

An in situ ductal carcinoma of the breast is the most frequent form of non-invasive breast cancer in women and is a risk factor or precursor for the development of invasive breast cancer. Therefore, the association between physical activity and this cancer would indicate that exercise could act as a protective factor in the early stages of the carcinogenesis process. However, it has been found that this is not the case.

Different results for invasive cancer

A previous study carr
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FECYT - Spanish Foundation for Science and Technology
Source:Eurekalert  

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