Navigation Links
Phase III pivotal results presented of VYVANSE to treat ADHD in adults
Date:5/8/2008

WASHINGTON, May 8 /PRNewswire-FirstCall/ -- Shire plc (LSE: SHP, Nasdaq: SHPGY), the global specialty biopharmaceutical company, today presented the results of a phase III pivotal study in which VYVANSE demonstrated significant improvements in Attention Deficit Hyperactivity Disorder (ADHD) symptoms in adults and met all safety and efficacy endpoints.

"Adults with ADHD often find it challenging to focus and organize during the day. The disorder may impact many aspects of their lives from career to family and personal commitments," said Lenard A. Adler, M.D., lead researcher in this study and director of the Adult ADHD program at the NYU Langone Medical Center, associate professor of psychiatry, neurology and child and adolescent psychiatry at the New York University School of Medicine, as well as author of Scattered Minds: Help and Hope for Adults with ADHD (G. P. Putnam's Sons 2006). "This study demonstrated that VYVANSE significantly improved ADHD symptoms in adults, including inattention, such as the ability to focus, organize and complete tasks, which are essential during an adult day, as well as hyperactivity, such as restlessness, and impulsivity."

This double-blind, placebo-controlled, four-week, forced-dose study in 414 adults aged 18 to 55 years showed that treatment with VYVANSE at all doses studied (30 mg, 50 mg, 70 mg) provided a significant reduction in ADHD Rating Scale (ADHD-RS-IV) scores within one week that were observed throughout the full treatment period. At endpoint, VYVANSE demonstrated a significant improvement in ADHD symptoms, based on a 43 percent reduction in ADHD-RS scores. This is the largest placebo-controlled stimulant trial of ADHD in adults conducted to date.

Additional Study Findings Investigators also measured the efficacy of VYVANSE with the Clinical Global Impressions-Improvement (CGI-I) scale and found that the percentage of subjects taking VYVANSE rated "much improved" or "very much improved"
'/>"/>

Contact: Lucia Lodato
lucia.lodato@porternovelli.com
917-617-3058
Porter Novelli
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Preliminary Results from Phase 2 Genzyme Study Highlight Potential of Novel Oral Compound for Gaucher Disease
2. NicOx Announces U.S. Phase 2a Results for PF-03187207 and Gives an Update on Continuing NO-prostaglandin Program
3. Phase 3 data Re: Anti-RSV antibody to be presented at Pediatric Academic Societies Annual Meeting
4. Wal-Mart Launches Phase Three of $4 Prescription Program
5. Sanofi-aventis: Encouraging First-Quarter 2008 Results Further Positive Phase III Results for Eplivanserin
6. Antipodean Pharmaceuticals Announces Results of Phase 2 Study of Lead Compound MitoQ(R)
7. Arpida Provides Comprhensive Overview of Pivotal Phase III Trial Data
8. QLT initiates phase II study of punctal plug drug delivery system for glaucoma & ocular hypertension
9. Cystic Fibrosis Foundation announces positive early results for phase 2 clinical trial of VX-770
10. Many Phase 3 Cancer Drug Trials Yield Effective Medicines
11. Cancer treatments in phase 3 trials successful up to half of the time
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... In its comprehensive analysis of medical ... Claim Review division have recently identified out-of-network and medical ... savings are achieved on behalf of employer-clients. , ... in savings to Argus each year, with a total ... by Tom Doney, Cypress president and CEO, these in-depth ...
(Date:12/17/2014)... Mamaroneck, NY (PRWEB) December 17, 2014 ... man who recently brought videos of MIT economist and ... and best-selling author James O’Keefe conducted the interview, which ... “Rich” stated that there was intentional mislabeling in the ... agenda in the bill: A two-hundred-and-fifty billion dollar per ...
(Date:12/17/2014)... Dec. 16, 2014 (HealthDay News) -- Expectant parents should ... and Drug Administration recommends. Use of ultrasound imaging ... is not entirely risk-free, the agency warns. ... harm due to ultrasound imaging and heartbeat monitors, prudent ... is important," Shahram Vaezy, an FDA biomedical engineer, said ...
(Date:12/17/2014)... HealthDay Reporter TUESDAY, Dec. 16, ... approaching, a new study reveals that states that routinely perform ... drivers on their roads. The finding suggests that states ... to deter inebriated revelers from getting behind the wheel in ... passed regarding drinking and driving," said study lead author James ...
(Date:12/15/2014)... OR (PRWEB) December 15, 2014 A ... by United States women as impacting skin health and ... “Four C’s of skin care.” Water and health advocate ... in a recent article describing the survey and the ... every item in every category discussed would benefit from ...
Breaking Medicine News(10 mins):Health News:Out-of-Network & Medical Necessity Reviews among Top Ways TPA Identifies Significant Medical Claim Savings 2Health News:Project Veritas: James O’Keefe Interviews the Man Who Discovered Jonathan Gruber Videos 2Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Enforcement of Drunk Driving Laws Makes Roads Safer, Study Finds 2Health News:Enforcement of Drunk Driving Laws Makes Roads Safer, Study Finds 3Health News:Water and health advocate Sharon Kleyne adds a “W” for fresh water to “four C’s of skin care” 2Health News:Water and health advocate Sharon Kleyne adds a “W” for fresh water to “four C’s of skin care” 3
... incidence of Alzheimer's disease nationwide, both the New York ... passed a resolution aimed at raising awareness of the ... this brain disorder. ,The resolution declared November ... 2007 as Memory Screening Day in New York State. ...
... export of herbal products and medicines has the potential to ... with the creation of exclusive export promotion zones (EPZ) ... exports can be accelerated with the setting up of EPZs ... a rate of over 25 percent in countries like the ...
... at the 61st Annual Meeting of the Society ... Corporation, announced the worldwide launch of the Cordis ... in angioplasty procedures for patients with carotid and ... unique high-pressure expansion and low profile .014 inch ...
... among asylum seekers in Denmark has proportionally tripled since 2001 ... a study published Thursday . ,Sixty-seven asylum seekers ... percent of the total -- tried to end their lives ... to Help Refugees said. ,That contrasted with the ...
... Titan, a TATA company, is in negotiations with Prof Vijay ... to the University of Arkansas, to start production of ... deal is yet to be finalized. ,Varadan holds ... and Neuro- Electronics, Sensors and Systems; High Density Electronics Center ...
... Project (MVP) today released new data on the performance ... suggesting that the new vaccine-- expected to sell initially ... effective in protecting African children and their communities than ... ,MVP, a partnership between the World Health ...
Cached Medicine News:Health News:New York Legislature Highlights for Awareness of Alzheimer's Disease 2Health News:New York Legislature Highlights for Awareness of Alzheimer's Disease 3Health News:Export of Herbal Products to Reach Rs.120 Billion by 2012: Study 2Health News:New Balloon Catheter Available Worldwide for Carotid and Renal Angioplasty 2Health News:Titan may Produce Glucose Watches Soon 2Health News:Improved Meningitis Vaccine for Africa Expected to End Deadly Scourge 2Health News:Improved Meningitis Vaccine for Africa Expected to End Deadly Scourge 3
(Date:12/15/2014)... and HERZLIYA PITUACH, Israel , ... (NASDAQ: IMNP ) announced today that its Board ... Board succeeding Dr. Daniel Teper who continues as ... member of Immune,s Board of Directors since 2013. ... am delighted to represent the interest of shareholders and to ...
(Date:12/15/2014)... N.Y. , Dec. 15, 2014 As ... SPL (Structured Product Labeling) markup language standard, content teams ... understanding and skills to work with the standard. Starting ... series of three webinars on the benefits and the ... one-hour webinars will be facilitated by Howard Shatz ...
(Date:12/14/2014)... 2014  ChartSpan, a consumer platform for patients managing ... iPad medical app in the United States ... ChartSpan is an iPhone and iPad ... and send electronic healthcare records. The product was built ... of waiting for the healthcare system to deliver on ...
Breaking Medicine Technology:Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 2Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 3Immune Pharmaceuticals Elects Daniel Kazado as New Chairman of the Board. 4Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 2Data Conversion Laboratory Helping Life Sciences Content Producers Understand the Impact and Benefits of Structured Product Labeling 3ChartSpan Becomes The Most Downloaded Medical App in America 2ChartSpan Becomes The Most Downloaded Medical App in America 3
... ST. LOUIS, March 14, 2011 Members served by Express ... pharmacy benefits account on their smart phones using a new ... Members can download the Express Rx app from ... including those on BlackBerry devices, can access the mobile-optimized website ...
... Streamline Health Solutions, Inc. (Nasdaq: STRM ... for hospitals, announced today that Rick Leach has been ... March 14, 2011. With more than 20 years of ... an extensive background in developing and marketing healthcare information ...
Cached Medicine Technology:New Application Offers Express Scripts Members Convenient Account Access Across a Broad Range of Mobile Phone Platforms 2Streamline Health Appoints Rick Leach as Senior Vice President and Chief Marketing Officer 2Streamline Health Appoints Rick Leach as Senior Vice President and Chief Marketing Officer 3Streamline Health Appoints Rick Leach as Senior Vice President and Chief Marketing Officer 4
... Forms strong flexible gels for ... clarifier: mixture of wide range ... water 10 mg/mL, clear, faintly ... molecular biology MP: 90 °C ...
Inquire...
Inquire...
... Melt), A low temperature agarose for ... , Optimal for in-gel restriction digestion/ligation and ... very manageable clear gel that provides excellent ... approximately 65°C and remains fluid at 37°C ...
Medicine Products: