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Pharmacyclics Reports Third Quarter 2008 Financial Results
Date:4/24/2008

a-bearing animal

models resulted in inhibition of tumor growth and significant

activity in animal models of arthritis.

-- Plan to initiate Phase 1/2 trial evaluating HDAC inhibitor, PCI-24781,

given orally in hematologic malignancies in second quarter of 2008.

-- Plan to file investigational new drug (IND) application for the

company's Factor VIIa inhibitor in the second half of 2008.

-- Plan to file IND application for the company's small molecule Btk

inhibitor in the second half of 2008.

Conference Call and Webcast Details

The Company will hold a conference call today at 4:30 p.m. EDT to discuss third quarter 2008 financial results and achievements. To participate in the conference call, please dial 800-497-0451 for domestic callers and 706-758-3306 for international callers and reference conference passcode, 43624853. To access the live audio broadcast or the subsequent archived recording, log on to http://ir.pharmacyclics.com. The archived version of the webcast will be available on the company's website for one month.

About Pharmacyclics

Pharmacyclics is a pharmaceutical company developing innovative products to treat cancer and other serious diseases. The company is leveraging its small-molecule drug development expertise to build a pipeline in oncology and other diseases based on a wide range of targets, pathways and mechanisms. More information about the company, its technology, and products can be found at http://www.pharmacyclics.com. Pharmacyclics(R), and the "pentadentate" logo(R) are registered trademarks of Pharmacyclics, Inc.

NOTE: Other than statements of historical fact, the statements made in this press release about our expected cash used in operations over the next four quarters, the initiation of and enrollment and future plans f
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SOURCE Pharmacyclics, Inc.
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