Navigation Links
Pharmacy researcher finds most popular weight-loss drug strongly alters other drug therapies
Date:12/10/2012

o metabolize a wide range of medicines including aspirin and the cancer drugs irinotecan and pentyl carbamate of p-aminobenzyl carbamate of doxazolidine.

"This study shows that orlistat profoundly alters the therapeutic potential of the anti-cancer drugs," Yan said. "In the case of the anti-cancer drugs, it weakens their effectiveness."

Prior or co-presence of orlistat with one of the anti-cancer drugs resulted in cancer cells being far more prolific.

"Alli-based interactions can be key factors in the efficacy of medicines," Yan said.

Yan was also interested in Alli's effects on aspirin and its use as a blood thinner. "Aspirin is used to treat blood clots. Yan predicated: "Orlistat would increase the therapeutic potential of aspirin, which may increase the tendency of bleeding."

This isn't the first time that Yan has found critical drug interactions in his studies.

In 2006, he discovered that the anti-viral drug Tamiflu would be rendered ineffective in patients also taking the anti-clotting drug Plavix. His published findings have resulted in new dosing regimens for patients who need both drugs.

Yan is one of the authors of the 6-volume Encyclopedia of Drug Metabolism and Interactions. This state-of-the-art integrated reference represents a global effort and presents more than 120 chapters by prominent authors from 11 different countries: the United States, Canada, United Kingdom, Germany, Australia, Singapore, India, Japan, France, Denmark, and Switzerland.


'/>"/>

Contact: Dave Lavallee
dlavallee@advance.uri.edu
401-874-5862
University of Rhode Island
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Women’s Excellence in Bladder Control Partners with University Compounding Pharmacy in Troy, MI to Help Women with Chronic Pelvic Pain Conditions
2. Owner of Meningitis-Linked Pharmacy Declines to Testify Before Congress
3. Company With Ties to Meningitis-Linked Pharmacy Recalls All Products
4. Company With Links to Meningitis-Linked Pharmacy Recalls All Products
5. Second Compounding Pharmacy Shut Down in Massachusetts
6. A Void In The Independent Pharmacy Industry Leads to Independent Rx Consulting, Powered by OurHelix
7. Pharmacy Robots Linked to Bacterial Contamination of Drugs
8. Boston College researcher looks to stop a deadly parasite in its tracks
9. Researchers develop novel 3-D culture system for inflammatory breast cancer
10. Speech-language researcher awarded top honors
11. Researchers craft tool to minimize threat of endocrine disruptors in new chemicals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/30/2014)... Florida (PRWEB) October 30, 2014 Timothy, ... visit to Pompano Beach firefighters, showing that you are ... , Timothy met firefighters Tracey and Carl at ... Galuppi’s Restaurant and the Pompano Beach Chamber of Commerce. ... the fire truck, letting Timothy wear his real fireman’s ...
(Date:10/30/2014)... San Diego, Calif. (PRWEB) October 30, 2014 ... no longer mutually exclusive concepts in the medical-grade ... focusing on the development of uniquely potent topical ... Skin Health System ( http://www.RefinitySkinScience.com ) with patented ... highest available glycolic acid concentrations (50% and 70%) ...
(Date:10/30/2014)... Paramount Rx, a full-service prescription benefits manager ... help people save money through its innovative discount card ... drugs in the new health care system, the Paramount ... the relationship between consumers, businesses and the pharmacy industry. ... face today with medical costs is the rising price ...
(Date:10/30/2014)... Tara Haelle HealthDay ... -- More than 100 genes have been identified that ... report. And researchers say they are on their ... may contribute to the disorder. Autism spectrum disorders ... and social difficulties and repetitive behaviors. An estimated one ...
(Date:10/30/2014)... Dr. Joseph Furlin MD, a certified obstetrician and gynecologist, ... OB GYN in Melrose Park, IL and OB ... information about each of the care services and practice areas ... English and Spanish. The navigation of the website is ... provide Dr. Furlin’s patients with important information regarding his care ...
Breaking Medicine News(10 mins):Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 2Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 3Health News:4-year-old InstaKNOT CEO Honors Local Firefighters with Community Support 4Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 2Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 3Health News:Cosmederm Redefines Peel Science Standard with Launch of Refinity® Skin Health System 4Health News:Paramount Rx Discount Card Program Provides Valuable Resources in Midst of Current Health Care Reform 2Health News:Paramount Rx Discount Card Program Provides Valuable Resources in Midst of Current Health Care Reform 3Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 2Health News:Discovery of 100-Plus Genes Tied to Autism May Improve Treatments 3Health News:Dr. Joseph Furlin Launches New Website with Information about Care Services 2
... myocardial perfusion imaging is common, and in many patients is ... a study in the November 17 issue of JAMA ... is being presented at the American Heart Association,s annual meeting. ... years, but along with the potential benefits has come an ...
... the gradual accumulation in the brain of amyloid-beta peptide which is ... protein known as APP, which is found in three forms. Most ... disease does not distinguish between the different forms of the ... Chemistry , show that amyloid beta peptide is actually created mainly ...
... Reporter , SUNDAY, Nov. 14 (HealthDay News) -- Moderate drinking ... than not drinking at all, according to a trio of ... in Chicago. Not only did male coronary bypass ... was also boosted by a cocktail now and then. ...
... , SUNDAY, Nov. 14 (HealthDay News) -- ... the brain alter how they view themselves and others, ... aptitude for introspection, researchers say. Georgetown University Medical ... of the five scattered brain regions that comprise what,s ...
... of adult smokers dramatically decreased during the past three ... more quitting and fewer picking up the habit, according ... Sessions 2010. The Minnesota Heart Survey, a population-based, serial ... between 3,000 and 6,000 participants in each of its ...
... do not get enough sleep have higher levels of ... researchers have found. Data from a recent study ... the American Heart Association Scientific Sessions in Chicago by ... School of Medicine. The results come from surveying ...
Cached Medicine News:Health News:Common for patients to undergo multiple cardiac imaging tests, with high cumulative radiation dose 2Health News:Common for patients to undergo multiple cardiac imaging tests, with high cumulative radiation dose 3Health News:'Magic number' 695 opens up new areas for Alzheimer's research 2Health News:A Little Alcohol May Help the Heart: Studies 2Health News:A Little Alcohol May Help the Heart: Studies 3Health News:Brain Organizes Itself for Introspection as Children Age: Study 2Health News:Smoking among some adults dropped dramatically in past three decades 2Health News:Smoking among some adults dropped dramatically in past three decades 3Health News:Smoking among some adults dropped dramatically in past three decades 4Health News:Smoking among some adults dropped dramatically in past three decades 5Health News:Smoking among some adults dropped dramatically in past three decades 6Health News:Poor sleep quality increases inflammation, community study finds 2Health News:Poor sleep quality increases inflammation, community study finds 3
(Date:10/30/2014)... LOS ANGELES , Oct. 30, 2014 /PRNewswire/ ... biopharmaceutical research and development company specializing in oncology, ... technology and its lead drug candidate, aldoxorubicin.  The ... A New Approach," will be given by ... the Sarcoma Oncology Center and principal investigator of ...
(Date:10/30/2014)... October 30, 2014 ... beim Aufbau von Kuhmilchverträglichkeit     Kuhmilchproteinallergie ... bei Säuglingen und Kleinkindern. Der bisher übliche ... Ernährung der Babys bzw. deren stillenden Mütter ... dass sich bei einer beträchtlichen Anzahl von ...
(Date:10/30/2014)... October 30, 2014 , Extensively ... cow milk   Cow milk protein allergy (CMPA) is the ... childhood. Until now, it has been managed by eliminating ... been shown that it is possible to help build ... number of children during the first year of life ...
Breaking Medicine Technology:CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 2CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 3CytRx Announces Oral Presentation at 2014 Chemotherapy Foundation Symposium 4Experten präsentieren neuste Forschungsergebnisse auf dem Allergy Day 2Experten präsentieren neuste Forschungsergebnisse auf dem Allergy Day 3Experts Present Latest Research at Allergy Day 2Experts Present Latest Research at Allergy Day 3
... Selective Kinase Inhibitor Phase 1 Trial in ... 9, 2008 EntreMed, Inc.,(Nasdaq: ENMD ... the treatment of cancer and inflammatory diseases, ... 1, dose-escalation study for its,selective kinase inhibitor, ...
... 2008 The Association,for Professionals in Infection Control ... MT, MPH, of Albany, NY, has been named,the ... Award.,APIC presents the annual award to an infection ... of Carole DeMille, a pioneer,in infection control. The ...
Cached Medicine Technology:EntreMed Achieves a Key Milestone Through Initiation of ENMD-2076 Clinical Program 2EntreMed Achieves a Key Milestone Through Initiation of ENMD-2076 Clinical Program 3EntreMed Achieves a Key Milestone Through Initiation of ENMD-2076 Clinical Program 4New York Infection Prevention Expert Named Recipient of Carole DeMille Award 2
...
Ascent Primary Knee System with cruciate retaining, posterior stabilized and constrained components...
The revision knee system for severe joint deterioration with insufficient ligament support....
The major innovations in posterior stabilized (PS) knee design....
Medicine Products: