Navigation Links
Pharmaceuticals: A market for producing 'lemons' and serious harm
Date:8/17/2010

of Prescription Drugs, which is scheduled for publication this fall by Columbia University Press.

In both his paper and his book, Light describes the "Risk Proliferation Syndrome" that is maximizing the number of patients exposed to new drugs that have relatively low efficacy and effectiveness but have greater risk of adverse side effects. Building on clinical trials designed to minimize evidence of harm and published literature that emphasizes a drug's advantages, companies launch massive campaigns to sell it, when a controlled, limited launch would allow evidence to be gathered about the drug's effects. Companies recruit leading clinicians to try using the drug for conditions other than those for which it is approved and to promote such off-label or unapproved uses. Physicians inadvertently become "double agents" promoters of the new drug, yet trusted stewards of patients' well-being, said Light. When patients complain of adverse reactions, studies show their doctors are likely to discount or dismiss them, according to Light.

Despite the extensive requirements for testing the efficacy and safety of each new drug, companies "swamp the regulator" with large numbers of incomplete, partial, substandard clinical trials, Light said. For example, in one study of 111 final applications for approval, 42% lacked adequately randomized trials, 40% had flawed testing of dosages, 39% lacked evidence of clinical efficacy, and 49% raised concerns about serious adverse side effects, said Light.

"Just recently, major reports have come out about biased, poor trials for Avandia and Avastin," Light said, who noted that orphan drugs are tested even less well.

"The result is that drugs get approved without anyone being able to know how effective they really are or how much serious harm they will cause," Light said. The companies control the making of scientific knowledge and then control which findings will go to the FDA or be published.

"A
'/>"/>

Contact: Daniel Fowler
fowler@asanet.org
202-527-7885
American Sociological Association
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. The malicious use of pharmaceuticals: An under-recognized form of child abuse
2. KPA and TK Carsites offer HR, OSHA and Internet Marketing Workshops at the NADA Convention and Expo 2010
3. Gael Announce Partner Opportunity in US Healthcare Market
4. TechCFO Enters Mid-Atlantic Market; Rick Rolandi Leads DC Metro Office
5. Home Health Care Newest Market Sector for Marketing/PR firm, Placemaking Group, With Addition of Client, Nursing and Rehab At Home
6. Bluegiga Expands to Health and Medical Market With the New Bluegiga eHealth Access Point
7. Your e-Marketing Journey in 2010: An e-Book for Corporate Communicators Working in European Headquarters
8. United Therapeutics Corporation Withdraws European Marketing Authorization Application for Tyvaso for the Treatment of Pulmonary Arterial Hypertension
9. Webmarketing 123 Profiled in National Study of High Growth Professional Services Firms
10. Farmers markets offer different strokes for different folks
11. Sun Spark Purity Moves Aggressively into the Market of Pure Lidocaine Powder and Caffeine Powder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... Abilene, Texas (PRWEB) December 26, 2014 Yisrayl ... has written an open letter in light of the Ferguson, ... year history of civil unrest and explains why it has ... the reason mankind was even created. He says there is ... in detail. Yisrayl also says there is a set of ...
(Date:12/26/2014)... 26, 2014 “Many people become overwhelmed ... injury claim issues and phone calls with insurance companies,” ... article featuring their free eBook on pedestrian and ... on pedestrian and bicycle auto accident claims assures the ... capable of professionally handling their case while they focus ...
(Date:12/26/2014)... 26, 2014 DW-InductionHeating.com (DaWei Induction Heating ... researching and developing, producing and marketing of a series ... business announces their new series of induction brazing ... the company, induction brazing refers to the ... filler material and heat. The manager says that there ...
(Date:12/25/2014)... This is a professional and in-depth ... industry with a focus on the Chinese market. The ... the Sterilizers manufacturers and is a valuable source of ... the industry. This report provides a basic overview of ... In this part, the report presents the company profile, ...
(Date:12/25/2014)... Dallas, TX (PRWEB) December 26, 2014 ... Analysis to 2023” focuses on the current treatment landscape, ... colorectal cancer market. TS-1 is an anti-cancer drug which ... administered orally and is also used for treating gastric ... gimestat and otastat potassium. The drug was first approved ...
Breaking Medicine News(10 mins):Health News:Yisrayl Hawkins Pleads for Peace in Ferguson and Beyond in New Open Letter 2Health News:Guide to Handling Pedestrian and Bicycle Accidents Released By The Jones Firm, Featured in Recent Article 2Health News:Induction Brazing Equipment Series From DaWei Induction Heating Co., A Reliable Supplier Of Induction Heating Equipment 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 3Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:TS-1 Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3
... 25 The HHS Office of HIV/AIDS Policy,s AIDS.gov will ... with a special focus on reducing HIV/AIDS-related stigma and promoting ... World AIDS Day will also mark the second anniversary of ... and resources. , , AIDS.gov ...
... guide treatment choices, researchers say , , TUESDAY, Nov. 25 ... genetic model for predicting the risk of recurrence in ... a team at the Duke Institute for Genome Science ... to chemotherapy and targeted therapy regimens. , The researchers ...
... available in Spanish . , A new ... the first time since the report was first issued in ... are decreasing for both men and women, driven largely by ... The report notes that, although the decreases in overall ...
... , , HARRISBURG, Pa., Nov. ... West Middlesex Area School District, the Pennsylvania Department of Health ... Middlesex Junior/Senior High School on Nov. 19 and Nov. 24. ... tetanus/diphtheria/pertussis vaccine was given to approximately 560 parents, students, and ...
... Gen-Probe Incorporated,(Nasdaq: GPRO ) announced today that the ... Conference on Tuesday, December 2, 2008 at,noon Eastern Time. The ... through a link on the investors section of Gen-Probe,s website ... days following,the event. , ...
... with chronic obstructive pulmonary disorder must weigh risks, benefits, ... A new review of existing data confirms that some ... with the lung disease known as chronic obstructive pulmonary ... raise the risk of pneumonia in patients with COPD, ...
Cached Medicine News:Health News:HHS' AIDS.gov to Use Blogs, Virtual Worlds, and Social Networks to Deliver HIV Information for World AIDS Day 2008 2Health News:Gene Test Could Predict Colon Cancer's Return 2Health News:Annual report to the nation finds declines in cancer incidence and death rates 2Health News:Annual report to the nation finds declines in cancer incidence and death rates 3Health News:Annual report to the nation finds declines in cancer incidence and death rates 4Health News:Annual report to the nation finds declines in cancer incidence and death rates 5Health News:Gen-Probe to Webcast Presentation at the 20th Annual Piper Jaffray Health Care Conference 2Health News:Steroid Inhalers Raise Pneumonia Risk for Lung Disease Patients 2Health News:Steroid Inhalers Raise Pneumonia Risk for Lung Disease Patients 3
(Date:12/24/2014)... 2014 Soligenix, Inc. (OTCQB: SNGX) (Soligenix ... products that address unmet medical needs in the ... that on December 24, 2014 it closed its ... Company raised approximately $2.3 million in gross proceeds ... net proceeds from the offering to fund its ...
(Date:12/24/2014)... , December 24, 2014 ... at an average rate of 8.1%. The US has ... knee and spine surgeries are the common orthopedic procedures ... have a lower penetration. Increased number of product recalls ... Non-metallic orthopedic devices have gained popularity in the industry ...
(Date:12/24/2014)... , December 24, 2014 ... on Global Disposable Syringe Industry of 178 ... online business intelligence library. The ... Syringe Industry is a professional and deep ...  For overview analysis, the report introduces Disposable ...
Breaking Medicine Technology:Soligenix Announces Closing of Public Offering of Units 2Soligenix Announces Closing of Public Offering of Units 3Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 2World Disposable Syringe Market 2014 Report: China and Regional Analysis 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 4World Disposable Syringe Market 2014 Report: China and Regional Analysis 5
... Reserve" May Also Affect,Alzheimer's Risk -, WASHINGTON, June ... treating risk factors for heart disease and stroke,such ... the progression,of Alzheimer's disease, according to research reported ... Prevention,of Dementia in Washington, DC. , Two new ...
... Jun 09, 2007 (MARKET WIRE via COMTEX ... owned subsidiary of Endo,Pharmaceuticals Holdings Inc. (NASDAQ: ... randomized, double-blind, placebo-controlled,clinical trial evaluating Frova (frovatriptan ... treatment in women with,difficult-to-treat menstrual migraine (MM). ...
Cached Medicine Technology:Treating Heart Disease Risk Factors May Slow Alzheimer's Disease,Progression 2Treating Heart Disease Risk Factors May Slow Alzheimer's Disease,Progression 3Treating Heart Disease Risk Factors May Slow Alzheimer's Disease,Progression 4Treating Heart Disease Risk Factors May Slow Alzheimer's Disease,Progression 5Treating Heart Disease Risk Factors May Slow Alzheimer's Disease,Progression 6Treating Heart Disease Risk Factors May Slow Alzheimer's Disease,Progression 7Frova Phase III Study Data Demonstrates That Short-Term Prevention,Treatment Reduces Frequency and Severity of Menstrual Migraine 2Frova Phase III Study Data Demonstrates That Short-Term Prevention,Treatment Reduces Frequency and Severity of Menstrual Migraine 3Frova Phase III Study Data Demonstrates That Short-Term Prevention,Treatment Reduces Frequency and Severity of Menstrual Migraine 4Frova Phase III Study Data Demonstrates That Short-Term Prevention,Treatment Reduces Frequency and Severity of Menstrual Migraine 5Frova Phase III Study Data Demonstrates That Short-Term Prevention,Treatment Reduces Frequency and Severity of Menstrual Migraine 6Frova Phase III Study Data Demonstrates That Short-Term Prevention,Treatment Reduces Frequency and Severity of Menstrual Migraine 7
... pacemaker family offers some ... automatic devices. Featuring the ... advanced technologies ever seen, ... incorporates the exclusive ventricular ...
... The SPOTCHEM EZ is a small bench ... Testing is performed on reagent strips with results ... is 48 tests per hour. The instrument accepts ... the swipe of a magnetic card. At the ...
... Veriteq's Refrigerator and Freezer Monitoring ... monitoring system for refrigerators and ... install. Using a building's existing ... Freezer monitoring solution automates the ...
The ThermaViewer™ is constructed and engineered for use in laboratories, hospitals, and commercial kitchens to monitor and document freezer and refrigerator temperatures where inventory is store...
Medicine Products: