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PharmaPoint: Pediatric Respiratory Syncytial Virus (RSV) Prophylactics - US Drug Forecast and Market Analysis to 2022
Date:9/18/2013

London (PRWEB) September 18, 2013

Summary

Respiratory syncytial virus (RSV) is a common cause of pediatric respiratory infections and virtually all children will have been infected by the virus by the age of two. RSV transmission typically occurs during the winter and early spring months. The virus is spread through the air by an infected person’s sneeze or cough, or through direct and indirect contact with nasal secretions of an infected person. The majority of RSV infections present as mild upper respiratory illnesses that often self-resolve within two weeks, but about 1% of the cases develop serious lower respiratory complications requiring hospitalization. Children under the age of two with certain health conditions are most at risk for severe RSV infections and are therefore recommended to receive RSV prophylaxis treatments. The only FDA-approved prophylactic intervention in the US is AstraZeneca’s Synagis (palivizumab), a humanized monoclonal antibody against the fusion protein of the virus.

Highlights

Key Questions Answered

  • What are the treatment algorithms and what do most pediatricians and neonatologists adhere to?
  • What unmet needs still remain and what do key opinion leaders think?
  • How likely is it that Synagis’ biosimilars will enter the market during the forecast period?
  • What promising interventions are in the pipeline for this narrow patient segment?
  • What are the likely changes in future guidelines as expected by key opinion leaders?

Key Findings

  • The majority of physicians adhere to the AAP guidelines limiting the number of doses and narrowing the use of Synagis
  • AstraZeneca, with Synagis, will continue its stronghold of the RSV market for the forecast period
  • Pipeline prophylactic indications will be first in class (active/maternal i
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