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PharmaPoint: Non-Small Cell Lung Cancer - UK Drug Forecast and Market Analysis to 2022
Date:11/4/2013

Overview 67
7.2 Promising Drugs in Clinical Development 67
7.2.1 onartuzumab (MetMab) 71
7.2.2 necitumumab (IMC-11F8) 77
7.2.3 ramucirumab (IMC-1121B) 82
7.2.4 custirsen (OGX-011) 86
7.2.5 ganetespib (STA-9090) 91
7.2.6 nintedanib (BIBF1120) 97
7.2.7 Gilotrif (afatinib) 101
7.2.8 dacomitinib (PF-00299804) 107
7.2.9 LDK378 111
7.2.10 Yervoy (ipilimumab) 116
7.2.11 nivolumab (BMS936558) 120
7.2.12 GSK1572932A (MAGE-A3 Cancer Immunotherapeutic) 126
7.2.13 Halaven (eribulin mesylate) 130
8 Market Outlook 135
8.1 United Kingdom 135
8.1.1 Forecast 135
8.1.2 Key Events 138
8.1.3 Drivers and Barriers 139
9 Appendix 142
9.1 Bibliography 142
9.2 Abbreviations 161
9.3 Methodology 165
9.4 Forecasting Methodology 165
9.4.1 Number of NSCLC Patients Currently Seeking Treatment 165
9.4.2 Percent Drug-treated Patients 166
9.4.3 Drugs Included in Each Therapeutic Class 166
9.4.4 Launch and Patent Expiry Dates 167
9.4.5 General Pricing Assumptions 168
9.4.6 Individual Drug Assumptions 171
9.4.7 Generic Erosion 179
9.4.8 Pricing of Pipeline Agents 180
9.5 Physicians and Specialists Included in This Study 182
9.6 Survey of Prescribing Physicians 184
9.7 About the Authors 185
9.7.1 Authors 185
9.7.2 Epidemiologists 186
9.7.3 Global Head of Healthcare 187
9.8 About GlobalData 188
9.9 Disclaimer 188
1.1 List of Tables

Table 1: Symptoms of Disease NSCLC 19
Table 2: Treatment Guidelines for NSCLC 21
Table 3: Stage Definitions for NSCLC 23
Table 4: Treatment Overview by Stage of Diagnosis for NSCLC 28
Table 5: Leading Treatments for NSCLC 34
Table 6: Product Profile – Alimta (pemetrexed disodium) 36
Table 7: Alimta SWOT Analysis, 2013 38
Table 8: Product
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