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PharmaPoint: Non-Small Cell Lung Cancer - UK Drug Forecast and Market Analysis to 2022
Date:11/4/2013

most promising sales potential
-Make more informed business decisions from insightful and in-depth analysis of drug performance
-Obtain sales forecast for drugs from 2012-2022 in the UK.

1 Table of Contents
1 Table of Contents 5
1.1 List of Tables 8
1.2 List of Figures 10
2 Introduction 11
2.1 Catalyst 11
2.2 Related Reports 12
2.3 Upcoming Related Reports 14
3 Disease Overview 15
3.1 Etiology and Pathophysiology 15
3.1.1 Etiology 15
3.1.2 Pathophysiology and Histology 15
3.1.3 NSCLC Biomarkers 16
3.1.4 Quality of Life 17
3.2 Symptoms 18
4 Disease Management 20
4.1 Treatment Overview 20
4.1.1 Diagnosis 21
4.1.2 Clinical Staging 22
4.1.3 Screening and Early Detection 24
4.1.4 Localized Procedures and Therapies 25
4.1.5 Systemic Chemotherapy 26
4.1.6 Targeted Therapy 26
4.2 UK 29
4.2.1 Diagnosis 29
4.2.2 Clinical Practice 29
5 Competitive Assessment 31
5.1 Overview 31
5.2 Strategic Competitor Assessment 32
5.3 Product Profiles – Major Brands, Chemotherapies 34
5.3.1 Alimta (pemetrexed disodium) 34
5.4 Product Profiles – Major Brands, Targeted Therapies 38
5.4.1 Iressa (gefitinib) 38
5.4.2 Tarceva (erlotinib hydrochloride) 43
5.4.3 Xalkori (crizotinib) 49
5.4.4 Avastin (bevacizumab) 53
6 Opportunity and Unmet Need 57
6.1 Overview 57
6.2 Improved Overall Survival and Less Toxicity 58
6.3 Treatments for Patients with Acquired TKI Resistance 59
6.4 Better Treatment Options for Squamous Patients 60
6.5 Preventing Relapse or Recurrence 60
6.6 More Efficacious Second-Line Therapies 61
6.7 Increased Availability of Mutation Testing 61
6.8 More Cost-Effective Therapies 62
6.9 Unmet Needs Gap Analysis 63
7 Pipeline Assessment 67
7.1
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