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PharmaPoint: Alzheimer’s Disease - US Drug Forecast and Market Analysis to 2022
Date:10/21/2013

apy 69
6.1.7 Behavioral Treatments 70
6.2 Gap Analysis 70
6.2.1 Disease Prevention 71
6.2.2 Diagnosis from Biomarkers 72
6.2.3 Behavioral Therapies 73
7 Pipeline Assessment 74
7.1 Overview 74
7.2 Early-Stage Pipeline Assessment 74
7.3 AD Pipeline by Mechanism of Action 77
7.4 Enzymatic Processing 77
7.5 Immunization 78
7.6 Anti-Aggregation 79
7.7 “Me-Too” 79
7.8 Novel Therapeutic Approaches 80
7.9 Technology Trends Analytic Framework 81
7.10 Promising Drugs in Clinical Development 82
7.10.1 Namenda XR 83
7.10.2 Arimenda 86
7.10.3 Gammagard Liquid 10% 89
7.10.4 Solanezumab 91
7.10.5 Gantenerumab 95
7.10.6 Crenezumab 100
7.10.7 TRx0237 103
7.10.8 MK-8931 107
7.10.9 EVP-6124 110
7.10.10 Lu AE58054 113
8 Market Outlook 117
8.1 United States 117
8.1.1 Forecast 117
8.1.2 Key Events 121
8.1.3 Drivers and Barriers 121
9 Appendix 125
9.1 Bibliography 125
9.2 Abbreviations 140
9.3 Methodology 147
9.4 Forecasting Methodology 147
9.4.1 Diagnosed AD patients 148
9.4.2 Percent Drug-treated Patients 148
9.4.3 Drugs Included in Each Therapeutic Class 149
9.4.4 Launch and Patent Expiry Dates 149
9.4.5 General Pricing Assumptions 150
9.4.6 Individual Drug Assumptions 150
9.4.7 Generic Erosion 156
9.4.8 Pricing of Pipeline Agents 156
9.5 Physicians and Specialists Included in this Study 158
9.6 About the Authors 159
9.6.1 Author 159
9.6.2 Global Head of Healthcare 160
9.7 About GlobalData 161
9.8 Disclaimer 161

List of Tables

Table 1:Symptoms of AD 32
Table 2:Guidelines for the Treatment of AD 39
Table 3:Most Prescribed Drugs for AD by Class in the Global Markets, 2012 40
Table 4:Leading Branded Treatment
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