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PharmaPoint: Alzheimer’s Disease - UK Drug Forecast and Market Analysis to 2022
Date:10/24/2013

Namenda 60
Table 12:Namenda SWOT Analysis, 2013 62
Table 13:Overall Unmet Needs - Current Level of Attainment 64
Table 14:Clinical Unmet Needs - Gap Analysis, 2013 71
Table 15:Technology Trends Analytic Framework for the AD Pipeline, 2012 81
Table 16:Comparison of Therapeutic Classes in Development for AD, 2013 81
Table 17:Comparison of Therapeutic Classes in Development for AD, 2013 82
Table 18:Product Profile - Arimenda 83
Table 19:Arimenda SWOT Analysis, 2013 85
Table 20:Product Profile - Solanezumab 86
Table 21:Solanezumab SWOT Analysis, 2013 89
Table 22:Product Profile - Gantenerumab 90
Table 23:Gantenerumab SWOT Analysis, 2013 94
Table 24:Product Profile - Crenezumab 95
Table 25:Crenezumab SWOT Analysis, 2013 97
Table 26:Product Profile - TRx0237 98
Table 27:TRx0237 SWOT Analysis, 2013 100
Table 28:Product Profile - MK-8931 101
Table 29:MK-8931 SWOT Analysis, 2013 104
Table 30:Product Profile - EVP-6124 105
Table 31:EVP-6124 SWOT Analysis, 2013 107
Table 32:Product Profile - Lu AE58054 108
Table 33:Lu AE58054 SWOT Analysis, 2013 110
Table 34:Sales Forecasts ($m) for AD in the United Kingdom, 2012-2022 112
Table 35:Key Events Impacting Sales for AD in the United Kingdom, 2012-2022 114
Table 36:AD Market in the United Kingdom - Drivers and Barriers, 2012-2022 114
Table 37:Key Launch Dates 137
Table 38:Key Patent Expirations 138

List of Figures

Figure 1:Atrophy of the Brain in AD 20
Figure 2:Key Pathological Features in AD Versus a Healthy Neuron 22
Figure 3:Non-Amyloidogenic Metabolism of APP 24
Figure 4:Amyloidogenic Metabolism of APP 25
Figure 5:Neurofibrillary Tangles 27
Figure 6:Oxidative Damage Due to Free Radicals 29
Figure 7:Strategic Competitor Assessment of the Marketed Products in AD, 2013 45
Figure 8:A
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