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PharmaPoint: Alzheimer’s Disease - UK Drug Forecast and Market Analysis to 2022
Date:10/24/2013

arly-Stage Pipeline Assessment 74
7.3 AD Pipeline by Mechanism of Action 76
7.4 Enzymatic Processing 77
7.5 Immunization 78
7.6 Anti-Aggregation 78
7.7 “Me-Too” 79
7.8 Novel Therapeutic Approaches 80
7.9 Technology Trends Analytic Framework 80
7.10 Promising Drugs in Clinical Development 81
7.10.1 Arimenda 83
7.10.2 Solanezumab 86
7.10.3 Gantenerumab 90
7.10.4 Crenezumab 94
7.10.5 TRx0237 98
7.10.6 MK-8931 101
7.10.7 EVP-6124 104
7.10.8 Lu AE58054 107
8 Market Outlook 111
8.1 United Kingdom 111
8.1.1 Forecast 111
8.1.2 Key Events 114
8.1.3 Drivers and Barriers 114
9 Appendix 118
9.1 Bibliography 118
9.2 Abbreviations 129
9.3 Methodology 135
9.4 Forecasting Methodology 135
9.4.1 Diagnosed AD patients 135
9.4.2 Percent Drug-treated Patients 136
9.4.3 Drugs Included in Each Therapeutic Class 136
9.4.4 Launch and Patent Expiry Dates 137
9.4.5 General Pricing Assumptions 138
9.4.6 Individual Drug Assumptions 139
9.4.7 Generic Erosion 144
9.4.8 Pricing of Pipeline Agents 144
9.5 Physicians and Specialists Included in this Study 145
9.6 About the Authors 146
9.6.1 Author 146
9.6.2 Global Head of Healthcare 147
9.7 About GlobalData 148
9.8 Disclaimer 148

List of Tables

Table 1:Symptoms of AD 31
Table 2:Guidelines for the Treatment of AD 38
Table 3:Most Prescribed Drugs for AD by Class in the Global Markets, 2012 39
Table 4:Leading Branded Treatments for AD, 2013 44
Table 5:Product Profile - Aricept 47
Table 6:Aricept SWOT Analysis, 2013 50
Table 7:Product Profile- Exelon 51
Table 8:Exelon SWOT Analysis, 2012 54
Table 9:Product Profile - Razadyne 56
Table 10:Razadyne SWOT Analysis, 2013 58
Table 11:Product Profile-
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