Navigation Links
PharmaChk Device for Substandard, Counterfeit Drug Detection Receives Saving Lives at Birth Transition-to-Scale Grant

Rockville, MD (PRWEB) August 07, 2014

With the potential to revolutionize how medicines regulators, customs agents, procurement agencies, warehouse personnel, health facilities, and other providers throughout the world detect poor-quality medicines, a new portable device called PharmaChk will be supported with a $2 million transition-to-scale grant from Saving Lives at Birth: A Grand Challenge for Development. The funding will help further PharmaChk’s development and bring it closer to commercial production and availability.

“The toll that poor-quality medicines take on global public health—particularly among the most vulnerable populations in the developing world—is staggering, with 99% of all maternal deaths occurring in developing countries,” said Ronald T. Piervincenzi, Ph.D., chief executive officer of the U.S. Pharmacopeial Convention (USP). “Helping to ensure patient access to good quality drugs—including those for used for neonatal care, to fight infectious diseases or to maintain good maternal health—is a leading priority for USP.”

Portable and easy-to-use, PharmaChk is being developed in conjunction with researchers at Boston University (BU) to detect and quantify active ingredients in medicines. The ability to screen for potential medicines quality problems can be a tremendous benefit to healthcare personnel treating patients and to regulators and health program officials responsible for tracking and ensuring the quality of their medicines. This holds especially true in Sub-Saharan Africa and in Asia where national borders are often porous and tracking the flow of medicines from country to country can be extremely challenging.

According to Patrick Lukulay, Ph.D., USP’s vice president of global health impact programs and director of the Promoting the Quality of Medicines (PQM) program funded by the U.S. Agency for International Development (USAID), “Having the appropriate amount of an active pharmaceutical ingredient is key for any medicine to be effective. A poor-quality medicine can be one without enough active ingredient, which can lead to both preventable disease progression and to the development of drug resistance in patients and the community. In other cases, a medicine may have the correct amount of active ingredient but be of poor quality—for example not dissolve properly or contain impurities—due to poor manufacturing or storage practices, which can also compromise the medicine’s ability to bring a clinical benefit to the patient.”

PharmaChk—which was named as one of Scientific American magazine’s “World Changing Ideas of 2013”—has been in development by scientists from Boston University (BU), with support from the PQM program and seed funding from the Saving Lives at Birth partnership. Building country capacity to address public health concerns posed by counterfeit and substandard-quality medicines has been a long-standing goal of PQM, a 10-year program managed by the USAID Office of Health Systems of the Bureau for Global Health, with the aim of strengthening country health systems and improving health outcomes. A scientific organization dedicated to creating quality standards for medicines, food ingredients and dietary supplements, USP works collaboratively with USAID to implement PQM.

Launched in 2011, the Saving Lives at Birth partnership includes USAID, the Government of Norway, the Bill & Melinda Gates Foundation, Grand Challenges Canada (funded by the Government of Canada), and the U.K’s Department for International Development. Saving Lives at Birth is a global call for groundbreaking, scalable solutions to prevent infant and maternal deaths around the time of birth and supports a wide variety of work across maternal and neonatal health, family planning, nutrition and HIV.

While other methods to screen for substandard or counterfeit products in the field are currently available, they are limited in their ability to quickly and accurately quantify the actual amount of active ingredient in a sample as well as to determine how quickly that active ingredient dissolves so it can work in the body as intended.

This past spring, the first pilot study using PharmaChk on medicine samples was conducted at USP’s Center for Pharmaceutical Advancement and Training (CePAT) in Accra, Ghana. USP opened CePAT in May 2013 to help expand the number of trained experts and available tools to combat substandard and counterfeit medicines that threaten nations in Sub-Saharan Africa.

The pilot study was conducted of samples of the antimalarial medicine artesunate, collected from three main medicine sources in Accra—public hospital/clinics, private retail/wholesale pharmacies, and informal outlets. USP and BU scientists are excited about early results from the pilot study, and plans are underway to further refine PharmaChk and to use the device to test samples of other medicines collected from the field.

Read the full story at

Source: PRWeb
Copyright©2014 Vocus, Inc.
All rights reserved

Related medicine news :

1. Daily Sun Exposure and Vitamin D Intake Simplified With Wearable Device
2. Exercise Device Helps With Squats - Designed by InventHelp Client (LGI-1774)
3. New hand-held device uses lasers, sound waves for deeper melanoma imaging
4. Laparoscopy Devices Market: Internal Closure Devices, Energy Systems, Trocars, Laparoscopes, Irrigation Systems, Insufflation Devices, Sample Retrieval Bags
5. J&J's Ethicon Unit Recalls its Power Morcellator Devices After Warnings by Federal Regulators and Concern About Risk of Spreading Occult Cancer, Parker Waichman Comments
6. Turkey Pharmaceutical and Medical Device Market Worth $21.5B & $3.3B by 2020 Respectively, Says a Report Available at
7. New Dental Device Reviews to Stop Snoring by VitalSleep
8. Have You Had a Hysterectomy or Removal of Uterine Fibroids? Morcellator Device Withdrawn From Market Due To Cancer Risk
9. Orthopedic Trauma Fixation Devices Market: Global Forecast, Share, Size, Growth and Industry Analysis 2014 - 2020
10. Loffler Companies Introduces New Konica Minolta bizhub PRESS C1085/C1100 and Canon imagePRESS C800/C700 Devices
11. NiQ Health Reveals the Extensive Use of Unregulated Medical Devices in Australian Hospitals
Post Your Comments:
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are ... Code Talker Award, an essay contest in which patients and their families pay tribute ... presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty ... Barry M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... and the most handsome men, look naturally attractive. Plastic surgery should be invisible.” ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital Partners, ... economy by obtaining investment capital for emerging technology companies. SCP has delivered ... already resulted in more than a million dollars of capital investment for five ...
(Date:6/24/2016)... ... June 24, 2016 , ... Venture Construction Group (VCG) ... held on June 20th at the Woodmont Country Club at 1201 Rockville Pike, ... organization dedicated to helping service members that have been wounded in battle and their ...
(Date:6/24/2016)... ... June 24, 2016 , ... Advanced Plastic Surgery Institute ( ... as its official Medspa Sponsor. Dr. Josh Olson, a board-certified plastic surgeon, owns ... Dr. Olson says the decision to support the pageant in an official capacity ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 The Academy of Managed ... recommendations that would allow biopharmaceutical companies to more ... that make formulary and coverage decisions, a move that ... new medicines. The recommendations address restrictions in ... on the drug label, a prohibition that hinders decision ...
(Date:6/24/2016)... 2016 Research and Markets has announced ... Diagnostic Tests" report to their offering. ... The World Market for Companion Diagnostics covers ... Market analysis in the report includes the following: ... Diagnostic Kits) by Region (N. America, EU, ROW), 2015-2020 ...
(Date:6/24/2016)... , June 24, 2016 ... appointment of Dr. Edward Futcher to ... Director, effective June 23, 2016.Dr. Futcher was also ... and Governance Committees.  As a non-executive member of ... expertise and strategic counsel to VolitionRx in connection ...
Breaking Medicine Technology: