Navigation Links
PharmAthene and Medarex Announce Additional $0.8 Million U.S. Government Appropriation for Continued Development of Anthrax Therapeutic Valortim(TM)
Date:11/6/2007

person, and then is believed to facilitate the entry of additional destructive toxins into the cells. Valortim is designed to target anthrax protective antigen and protect the cells from damage by the anthrax toxins.

Valortim has been administered intravenously and intramuscularly to 46 healthy human volunteers in a completed phase I study, was well tolerated at doses as high as 20 mg/kg (IV), and was not immunogenic. The Phase I data showed that Valortim was safe and well-tolerated. No drug-related Grade 2-4 or serious adverse events were reported. Grade 1 adverse events were reported in 16 of the volunteers overall, with the most common being pain/burning at the injection site for those being dosed intramuscularly (6 subjects). There were also a few mild headaches (3 subjects overall). Pharmacokinetic analysis suggested that doses as low as 1 mg/kg resulted in circulating levels of antibody after a month, with a similar potency for neutralizing anthrax toxin in vitro as was seen with serum obtained from subjects who had been vaccinated with anthrax vaccine. These study results were presented at the 2006 Annual Meeting of the Infectious Diseases Society of America.

Preclinical studies suggest that Valortim has the potential to provide protection against anthrax infection when administered prophylactically (prior to the emergence of symptoms of anthrax infection) and also the potential to be administered therapeutically (once symptoms become evident).

About Anthrax

According to the Centers for Disease Control and Prevention, anthrax is an acute infectious disease caused by the spore-forming bacterium Bacillus anthracis. Anthrax most commonly occurs in hoofed mammals and can also infect humans. Symptoms of disease vary depending on how the disease is contracted, but usually occur within seven days after exposure. The serious forms of human anthrax are inhalation anthrax, cutaneous anthrax, and intestinal anthrax. Initial symptoms of inhalatio
'/>"/>

SOURCE PharmAthene, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. PharmAthene to Present at the Rodman and Renshaw/Acumen BioFin 9th Annual Healthcare Conference
2. Ono and Medarex Announce Allowance of Investigational New Drug Application for Fully Human Anti-PD1 Antibody
3. Medarex to Present at the JPMorgan Small/Mid Cap Conference
4. HHS Announces $75 Million in Supplemental Funding to States for Pandemic Flu Preparedness
5. CRC Health Group Announces Acquisition of Bayside Marin Recovery Center, San Rafael
6. UHW Announces: Antelope Valley Hospital Caregivers and Board Vote to Ratify First Union Contract With SEIU UHW-West
7. HEI, Inc. Announces Sale of RFID Division Assets
8. Caraco Pharmaceutical Laboratories, Ltd. Announces FDA Approval to Market Generic Version of Zyloprim(R)
9. Mettler-Toledo International Inc. Announces Webcast of Presentation at Thomas Weisel Partners 2007 Healthcare Conference
10. Z Trim Announces Revocation of Gregory Halpern Severence Agreement
11. Brooke Franchise Corporation Announces Selected July Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... (PRWEB) July 23, 2014 The puffiness ... diminished using non-surgical techniques, according to a new guide ... eyes serum sold in the U.S. is now available ... . , The complimentary guide that is now published ... struggle with under eye puffiness. While surgical techniques are ...
(Date:7/23/2014)... near Sellafield or Dounreay since the 1990s are not ... research published in the British Journal of Cancer ... Research Group at the University of Oxford and from ... among those who were under 25 and living near ... in cancer incidence from 1991-2006 between those living near ...
(Date:7/23/2014)... 23, 2014 Home Care ... of in-home care for seniors, announces the next ... featuring experts in a wide range of health ... licensed clinical social worker and award-winning author Nancy ... of caregiver stress and ways to prevent burnout ...
(Date:7/23/2014)... Lake Worth, FL (PRWEB) July 23, 2014 ... will take place Aug. 10-16, Millennium Treatment Group is ... Substance abuse has existed in society ever since man ... make wine. Substance abuse treatment has existed since shortly ... of recognizing a problem and then developing a way ...
(Date:7/23/2014)... Alan Mozes HealthDay Reporter ... servicemen are more likely to have been exposed to some ... new survey suggests. The finding seems to apply solely ... that the finding could be a cause for concern, given ... and/or sexual abuse among the civilian population has been linked ...
Breaking Medicine News(10 mins):Health News:Puffy Eyes Serum Explored in Complimentary Guide Released at Consumer News Website 2Health News:Oklahoma Home Care Assistance Hosting Caregiver Mindfulness Webinar Tomorrow 2Health News:Oklahoma Home Care Assistance Hosting Caregiver Mindfulness Webinar Tomorrow 3Health News:Millennium Treatment Group Offers Tips on Choosing a Reputable Treatment Center 2Health News:Millennium Treatment Group Offers Tips on Choosing a Reputable Treatment Center 3Health News:Many U.S. Male Soldiers Had Troubled Childhoods, Study Finds 2Health News:Many U.S. Male Soldiers Had Troubled Childhoods, Study Finds 3
... Allscripts-Misys Healthcare,Solutions, Inc. (formerly named Allscripts Healthcare ... Delaware ("Allscripts") and,headquartered in Chicago, Illinois announced today ... 3.50% Convertible Senior Debentures due 2024 (the,"Debentures") at ... equal to 100% of the principal amount of ...
... 7 Sagent Pharmaceuticals, Inc.,a privately-held specialty pharmaceutical company ... and Chief Executive,Officer Jeffrey M. Yordon will be presenting ... as follows., November: -- Jeffrey M. ... Annual Healthcare Conference on Wednesday, ...
... BioActiveX3 Complex(TM) features toxin-free ingredients, green chemistry technology in self-adjusting ... ... SALT LAKE CITY, Nov. 7 Global nutrition leader XanGo,LLC, today ... international convention in Salt Lake City. This personal care,brand features exclusive ...
... Society of ... Nephrology, HAYWARD, Calif., ... indicating that,its therapeutic product candidate AC-200 improved bone architecture in a,rat model ... was evaluated in a well accepted rodent model of,chronic kidney disease (CKD) ...
... Inc.,(Nasdaq: ENMD ) a clinical-stage pharmaceutical company ... diseases,announced today that James S. Burns, President and ... the Rodman and Renshaw 10th Annual,Healthcare Conference, which ... New,York Palace Hotel in New York, NY. Mr. ...
... CHICAGO, Nov. 7 Easter Seals elected Missouri resident,Kent ... board,s,recent meeting., "Kent is a passionate advocate for ... from Easter Seals services and as a,volunteer leader," said ... Seals. "He is a dedicated board member, donor and,fund ...
Cached Medicine News:Health News:Allscripts Announces Notice of Offer to Purchase in Cash 3.50% Convertible Senior Debentures due 2024 2Health News:Allscripts Announces Notice of Offer to Purchase in Cash 3.50% Convertible Senior Debentures due 2024 3Health News:Allscripts Announces Notice of Offer to Purchase in Cash 3.50% Convertible Senior Debentures due 2024 4Health News:Sagent Pharmaceuticals Announces Presentations at Upcoming Lazard Capital Markets and Piper Jaffray Healthcare Conferences 2Health News:XanGo Introduces Glimpse(TM) Intuitive Skin Care 2Health News:XanGo Introduces Glimpse(TM) Intuitive Skin Care 3Health News:Acologix AC-200 Demonstrates Positive Effect on Bone in Preclinical Model of Chronic Kidney Disease 2Health News:Acologix AC-200 Demonstrates Positive Effect on Bone in Preclinical Model of Chronic Kidney Disease 3Health News:EntreMed to Present at the Rodman and Renshaw 10th Annual Healthcare Conference 2Health News:Easter Seals Elects Kent Schien, Chief Executive Officer of St. Louis-based Innoventor, to the Organization's International Board of Directors 2
(Date:7/23/2014)... , July 23, 2014 Research ... "Disposable Medical Gloves (Exam and Surgical) Markets Worldwide ... http://photos.prnewswire.com/prnh/20130307/600769 The purpose of ... market for Disposable Medical (Exam and Surgical) Gloves. The ... market for these products. Topics covered include ...
(Date:7/23/2014)... 23, 2014  The management team at Columbia ... hold a conference call on July 31, 2014, ... ended June 30, 2014.  The call details are ... 8:30 am EDTDial-in numbers: , Toll free: (877) ... (live & archive): , www.columbialabs.com , under ...
(Date:7/23/2014)...  Silk Road Medical, Inc., a developer of ... and extra-cranial cerebrovascular disease, announced today the appointment ... position of Chief Technology Officer.  In this new ... Development efforts across its family of transcarotid access ... joining Silk Road Medical, Michael was the Vice ...
Breaking Medicine Technology:Disposable Medical Gloves (Exam and Surgical) Markets Worldwide 2014 2Disposable Medical Gloves (Exam and Surgical) Markets Worldwide 2014 3Disposable Medical Gloves (Exam and Surgical) Markets Worldwide 2014 4Columbia Laboratories to Discuss Second Quarter 2014 Financial Results on July 31st Conference Call 2Silk Road Medical Appoints Ground Breaking Innovator as Chief Technology Officer 2Silk Road Medical Appoints Ground Breaking Innovator as Chief Technology Officer 3
... announces that a new market research report is available ... of Xylose in China http://www.reportlinker.com/p0260046/Production-and-Market-of-Xylose-in-China.html ... global financial crisis in Q4 2008, Chinese xylose production ... or even stopped production due to declining profit and ...
... improve vision-related quality of life in children compared with ... according to data drawn from a three-year multi-site study ... the self-perception of nearsighted children ages eight to 11 ... may be more considerable after 10 years of age. ...
Cached Medicine Technology:Reportlinker Adds Production and Market of Xylose in China 2Reportlinker Adds Production and Market of Xylose in China 3Children Report Better Vision-Related Quality of Life with Contact Lenses vs. Glasses 2
... Featured Products are kept ... and are offered as ... regular or extra long ... with insulation, flush ports, ...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Operate with confidence. Autosuture is advancing the sate of both open and minimally invasive surgery by providing surgical tools that feel right, function right, and facilitate the right outcome eve...
Medicine Products: