Navigation Links
Personalizing biologic treatment to individual patients with rheuatoid arthritis is cost-effective
Date:6/7/2012

Berlin, Germany, June 7 2012: Data presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism, demonstrates that tailoring biologic treatment to individual patients with rheumatoid arthritis (RA) can reduce total costs by 2,595,557 per 272 patients over 3 years (95 percentile range -2,983,760 to -2,211,755), whilst increasing effectiveness by an average of 3.67 quality-adjusted life years (QALYs)*. Cost savings were mostly on drug costs.

The Dutch study, which investigated 272 patients with RA starting adalimumab treatment, measured DAS28** HAQ*** and biologic use over three years. A treatment protocol for personalised care was defined in which EULAR**** response and adalimumab serum drug level test results at six months determined whether adalimumab treatment was continued or discontinued, dosing was altered or, in case of non-response, another biological treatment was started. Using a patient level Markov model, outcomes in DAS28, HAQ, and biologic use for the personalised care group were simulated and compared to the observed drug use and disease course.

Charlotte Krieckaert from the Jan van Breemen Research Institute, Reade, The Netherlands and lead author of the study stated: "Governments and health authorities around the world are looking to save money by cutting costs and providing reduced access to more expensive treatments. This study demonstrates that with careful monitoring and testing disease activity at six months, costs for RA treatment can be reduced and treatment effectiveness can actually increase."

In total, 2,562,494 was saved on biological drug costs and testing costs amounted to 10,872, resulting in an average incremental cost-effectiveness ratio (ICER)***** of -707,236 per QALY gained. Personalised care saved costs and was more effective in 77.6% of simulations, but was cost saving and less effective in 22.4%.


'/>"/>

Contact: Candice Debleu
eularpressoffice@cohnwolfe.com
44-789-438-6425
European League Against Rheumatism
Source:Eurekalert

Page: 1

Related medicine news :

1. Personalizing cancer: Creating biomarkers from tumor DNA
2. Personalizing medicine to prevent pandemics
3. Mayo researchers find biomarkers for personalizing radiation cancer treatment
4. Study carried out into biological risks of eating reptiles
5. Biological clock could be a key to better health, longer life
6. New method to grow arteries could lead to biological bypass for heart disease
7. Biologic Joint Reconstruction Using Stem Cells Proven Successful In Patients With Arthritis
8. U of T researchers crack splicing code, solve a mystery underlying biological complexity
9. Adolescent brains biologically wired to engage in risky behavior, study finds
10. Biologics-naive juvenile idiopathic arthritis patients have elevated risk of cancer
11. Length of biological marker associated with risk of cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2017)... ... August 23, 2017 , ... This week the The Voss Law Firm celebrates ... Bill Voss, the firm grew quickly and has built a reputation for excellence, trust, ... get the money they deserve from their insurance companies. , The Voss Law ...
(Date:8/23/2017)... DC (PRWEB) , ... August 23, 2017 , ... ... Oxygen Therapy continues to prove the safety and efficacy of HBOT in treating ... clinics across the US, points to research showing the similarities of the wounds ...
(Date:8/23/2017)... ... August 23, 2017 , ... PreCheck, Inc., ... 2017 Inc. 5000 with a three-year sales growth of 49 percent . ... and comprises the most comprehensive look at America’s independent entrepreneurs. This represents PreCheck’s ...
(Date:8/23/2017)... ... 2017 , ... MobilityWorks ®, the nation's largest retailer ... Inc. 500|5000, an exclusive ranking of America’s fastest-growing private companies. MobilityWorks (aka WMK) ... the twelfth year that the company has been included on the list. , ...
(Date:8/23/2017)... ... August 23, 2017 , ... A new literature review ... , points out that therapeutic modalities (physical therapy) is an important part of ... report, a wider scope of physical therapy options is showing promising results and ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... 15, 2017   Mostyn Law and Gulf Coast Regional ... Texas . The Mostyn Law family has had ... That is why Mostyn Law is partnering with Gulf ... show its appreciation. Blood supplies are running low. Gulf ... of hospital needs in August. That is why the blood center ...
(Date:8/14/2017)... Israel , Aug. 15, 2017  BrainStorm ... adult stem cell technologies for neurodegenerative diseases, announced financial ... "We are in ... 3 trial to investigate NurOwn ® in ALS," ... Officer of BrainStorm. "We have agreements with Mass. General ...
(Date:8/7/2017)... Aug. 7, 2017 Insightin Health, provider ... retention, and engagement, announced the selection of ... Product Development, effective as of February 2017. In this ... implementation strategy for our clients. Wood brings with ... consulting and business analytics within the healthcare industry. ...
Breaking Medicine Technology: