Navigation Links
Personalized medicine: Tumor analysis reveals new opportunities for existing cancer drugs
Date:11/16/2010

Targeted cancer therapies such as trastuzumab (Herceptin), gefitinib (Iressa) and erlotinib (Tarceva) could be used to treat a wider range of cancers than previously thought, according to new research presented today (Wednesday) at the 22nd EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Berlin.

Scientists in the USA have studied 20 genes that are targeted by existing therapies and found that there are significant changes to these genes in a broad range of patients' tumours, including many for which these drugs are not being used at present. The results suggest that these therapies, which have already been deemed safe and effective by regulatory agencies, may have additional opportunities to benefit cancer patients.

However, Dr Daniel Rhodes, chief executive officer and co-founder of Scientific Applications at Compendia Bioscience (Ann Arbor, Michigan, USA), told the meeting: "While there may be immediate opportunities to use these new findings to treat patients with few remaining treatment options, broader application of the findings will require large-scale clinical trials to investigate if such personalised medicine could translate into real benefit over existing standard of care."

Genes can play a role in causing cancer in a number of ways, including via mutations that cause them to function incorrectly or via DNA amplifications whereby there are multiple additional copies of a gene. Normal cells (apart from germ cells) typically have two copies of each gene, but cancer cells often create additional copies of specific cancer-causing genes. For the current study, Dr Rhodes and his colleagues were looking for tumours in which there were five or more copies of a particular gene.

Targeted therapies are aimed at blocking the action of the mutated or amplified genes, "but they are often used without detailed knowledge of the genetic makeup of a patient's tumour," said Dr Rhodes. "The aim of persona
'/>"/>

Contact: Emma Mason
wordmason@mac.com
ECCO-the European CanCer Organisation
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. GUMCs Lombardi Hosts Symposium Exploring Future of Cancer Research and Personalized Medicine
2. Johns Hopkins scientists develop personalized blood tests for cancer using whole genome sequencing
3. DSM Personalized Nutrition Webinar Explores Benefits of Nutrition for Employee Health
4. Personalized Live on-Demand Yoga Avatar Gains Popularity Amongst Users, Across all age Groups
5. Small Nutritional Changes are a Key to Health, Weight Loss, says DSM Personalized Nutrition
6. TGen Drug Development partners with Horizon Discovery for integrated personalized medicine service
7. Personalized medicine for cancer patients in a new technology era
8. Pediatric personalized medicine takes center stage at first-of-its-kind international conference
9. DSM Personalized Nutrition Webinar Examines Ways to Build Engagement in Wellness Programs
10. Myth Debunked: Baby Shower Gifts CAN Be Personalized Without Knowing Name Or Gender
11. Advances in personalized medicine take center stage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/18/2014)... (PRWEB) September 18, 2014 With ... have special functions of adjusting human body physiology, ... won great popularity with a variety of specific ... food in China reached RMB187.4 billion, up 12.0% ... during 2006-2013. , View Full Report at ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 SpineFrontier ... team and surgeon partners in Less Exposure Surgery ... SpineFrontier, Tamara authored an extensive education curriculum and ... Masters in Science in Organizational Leadership, and has ... for eleven years. Bringing her to the team ...
(Date:9/18/2014)... Dr. Suzaunna Clark, Psychologist, Life Coach and Licensed ... to be seen to be believed and 2- that ... be used. Together, both lead to hearts that heal. ... do both. , Dr. Clark offers professional ... system, which provides professional guidance on dealing with everyday ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 Specialty ... in Westlake, OH, announces that they have achieved ... PowerServer, a Complete Certified Ambulatory EHR-certified system developed ... Specialty Teleradiology had a non MU compliant PACS ... their business grew from a niche in oncology ...
(Date:9/18/2014)... (PRWEB) September 18, 2014 N-Zyme Scientifics ... successfully launching its first product a mere 8 months ... is a high performance glycan release enzyme used in ... research, and the basis for tissue pathology on Mass ... (Portsmouth, NH) for the North American market (PNGase F ...
Breaking Medicine News(10 mins):Health News:China Health Food Industry Size 2014 Market Analysis, Growth, Trends and Forecast Report 2017: MarketResearchReports.biz 2Health News:China Health Food Industry Size 2014 Market Analysis, Growth, Trends and Forecast Report 2017: MarketResearchReports.biz 3Health News:China Health Food Industry Size 2014 Market Analysis, Growth, Trends and Forecast Report 2017: MarketResearchReports.biz 4Health News:SpineFrontier Inc. Makes Bold Move to Expand Its Internal Training Team to Collaborate With The LESSociety’s Less Exposure Surgery® University To Educate Surgeons. 2Health News:Suzaunna-Where Life! Happens Announces the Launch of Healing Hearts 2Health News:Suzaunna-Where Life! Happens Announces the Launch of Healing Hearts 3Health News:Specialty Teleradiology Attains Meaningful Use with PowerServer MU 2Health News:Specialty Teleradiology Attains Meaningful Use with PowerServer MU 3Health News:N-Zyme Scientifics Announces Successful Product Launch 2
... malnourished in Haiti, which has earned the sobriquet of ... typical signs of malnutrition include swollen bellies, orange hair, ... M.D., associate clinical professor of pediatrics at Washington University ... something about the situation and founded Meds & Food ...
... been awarded a tender to import the H5N2 vaccine for ... Ministry awarded the tender to the company, as the company’s ... among the bidding companies. The company has planned to ... weeks after the receipt of the letter from the government. ...
... to a study published on August 3, 2006, by researchers ... school students// who are physically more active show better academic ... American College of Sports Medicine has published the findings of ... Medicine & Science in Sports & Exercise. ,In ...
... help a 92-year-old woman to commit suicide.// ,Ramesh ... in court to face the charge following investigations into the ... (RCMP). ,Sharma, according to media reports, was helping ... staff member interrupted them. ,Sharma, who appeared in ...
... soft drinks in educational institutions in the state.// ... all educational intuitions in the state from Friday," Rajasthan Education ... applies to 100,000 government and private institutes where over 15 ... continue till it is proved that the contents in the ...
... Zealand have significantly reduced the number of people going for ... said that the poker machine revenue fell 28%. He also ... from pub charities to various sports and other community groups. ... calls received by the gambling helpline also reduced drastically from ...
Cached Medicine News:Health News:Crusade Against Malnutrition 2Health News:Crusade Against Malnutrition 3Health News:Physical Activity Determines Academic Performance 2Health News:Indo-Canadian Doctor Charged with Abetting Suicide Bid 2
(Date:9/17/2014)... , Sept. 17, 2014  Decision ... colitis (CD/UC) patients eligible for biologic therapy, ... a biologic. Surveyed gastroenterologists cite patients, discomfort ... for low penetration rates, followed by cost-related ... UC patients receiving biologics, Janssen Biotech,s Remicade ...
(Date:9/17/2014)... , Sept. 17, 2014 ACIST Medical Systems, ... leader of advanced imaging modalities for cardiology, showcased the ... two live cases at the Transcatheter Cardiovascular Therapeutics meeting ... were presented from Medstar Washington Hospital Center ( ... Medical Center ( New York, NY ). ...
(Date:9/17/2014)... , Sept. 17, 2014  Bayer HealthCare will ... Hemophilia Foundation,s 66 th Annual Meeting, which takes ... D.C.  The data, which will be shared through poster ... and patient care. Data will be presented in a ... into treatment modalities in hemophilia A patients, Bayer is ...
Breaking Medicine Technology:The Majority of Surveyed Gastroenterologists Agree that Biologics Should be Prescribed to More Patients in the Crohn's Disease and Ulcerative Colitis Treatment Paradigm 2The Majority of Surveyed Gastroenterologists Agree that Biologics Should be Prescribed to More Patients in the Crohn's Disease and Ulcerative Colitis Treatment Paradigm 3ACIST Launches HDi High-Definition IVUS 2ACIST Launches HDi High-Definition IVUS 3Bayer to Present Data on Hemophilia Research at NHF in Washington, D.C. 2Bayer to Present Data on Hemophilia Research at NHF in Washington, D.C. 3Bayer to Present Data on Hemophilia Research at NHF in Washington, D.C. 4
... Nov. 1, 2010 Hologic, Inc. (Hologic or ... leading developer, manufacturer and supplier of premium diagnostics ... to serving the healthcare needs of women, today ... Society of Breast Surgeons (ASBS) MammoSite® Breast Brachytherapy ...
... Nov. 1, 2010 Inovonics ( http://www.inovonics.com ), the ... commercial and life safety applications, today announced the ... sensor solution designed specifically to meet the unique ... motion-sensing technology, the EN1240 offers a significant advancement ...
Cached Medicine Technology:Hologic Announces Long-term, Five-year Results from MammoSite® ASBS Registry Study 2Hologic Announces Long-term, Five-year Results from MammoSite® ASBS Registry Study 3Inovonics Delivers Passive Wireless Sensor for Monitoring Senior Care Resident Activity 2Inovonics Delivers Passive Wireless Sensor for Monitoring Senior Care Resident Activity 3Inovonics Delivers Passive Wireless Sensor for Monitoring Senior Care Resident Activity 4
The Biopro Cox comb cup is manufactured from titanium and is porous coated on the outside of the shell. The Cox comb cup accommodates a polyethylene insert....
The MPF cup is specifically designed to achieve high primary stability, a critical factor for long term success....
The Trilogy system builds on the success of the Harris/Galante Porous and HGP II cups by combining proven features with new technology designed to inhibit the formation and migration of polyethylene ...
For primary and revision cases...
Medicine Products: