Navigation Links
Perforomist-comparable pharmacokinetic and pharmacodynamic profile to DPI formulation
Date:5/20/2008

Napa, CA (May 20, 2008) Data presented today at the International Conference of the American Thoracic Society (ATS) demonstrate that Perforomist™ Inhalation Solution (formoterol fumarate inhalation solution; FFIS) has a pharmacodynamic and pharmacokinetic profile that is comparable to the dry powder inhaler (DPI) formulation of formoterol fumarate, Foradil® Aerolizer® 12 g (FA).

Perforomist™ (formoterol fumarate) Inhalation Solution, the only FDA-approved nebulized formoterol fumarate, was approved in 2007 by the FDA for long-term, twice-daily maintenance treatment of bronchoconstriction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.

The first of the two studies presented, Dose-Ranging Study in COPD Patients Comparing Pharmacodynamics of Formoterol Fumarate Delivered by Nebulization and DPI, showed that 20 g of FFIS (Perforomist™ Inhalation Solution) delivered by nebulization provides bronchodilation comparable to DPI delivery.

The second study; A Pharmacokinetic Study in COPD Patients Comparing Formoterol Fumarate Delivered by Nebulization and DPI, showed comparability in linear kinetics and excreted drug levels between formoterol fumarate administered by nebulization and DPI. Transient and dose-related effects on serum potassium, serum glucose and vital signs were observed and found to be comparable between the two formulations.

Dr. Nicholas J. Gross, MD, PhD, Hines VA Hospital, Stricht Loyola School of Medicine and lead clinical investigator in the first study, commented, The results of both of these studies provide additional evidence of the clinical benefit of Perforomist™ Inhalation Solution as a valuable treatment option for patients with COPD. Nebulization is an alternative way to deliver medication to the lungs and since many patients may have difficulty coordinating the use of other devices as their disease progresses, n
'/>"/>

Contact: Amy Techtmann
amy.techtmann@fkhealth.com
617-761-6784
Feinstein Kean Healthcare
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Phase I pharmacokinetic study of ECO-4601, a novel bifunctional targeting agent
2. Fry Construction Selected for High-Profile Medical Imaging Project
3. CIGNA Behavioral Health Offers Members Online Provider Profiles
4. Los Angeles Jewish Home Support Group Continues High-Profile Speaker Program With Noted Legal Scholar and Expert Laurie L. Levenson
5. Waterville Investment Research Profiles Impact Medical Solutions
6. ENDEAVOR IV achieves primary endpoint, demonstrates similar safety profile compared to Taxus stent
7. INVEGA(TM) Shows Favorable Long-Term Safety Profile in a One-Year Study of Patients With Schizophrenia
8. Randone Trasylol Lawsuit Profiled on CBS 60 Minutes
9. MHA Announces Initial Results of the Specialty Pharmacy Member Profile Initiative
10. GSK Data Suggests Efficacy of Advair(R) and Serevent(R) is Not Impacted by Genetic Profile
11. Photos: Compact Barbell System With Flat, Streamlined Profile Travels Easily and Stores Conveniently
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... 2014 Medical Alert Systems, http://www.medicalalert-systems.com/ ... of some of the most popular medical alert devices ... announce that it is now offering special deals and ... are on a fixed income but would like to ... as very welcome news. , As a company spokesperson ...
(Date:8/20/2014)... (PRWEB) August 21, 2014 Angeldress.co.uk is ... in the international market. It has earned the trust ... quality products with amazing pricing. Recently, it has unveiled ... dresses online. , This time, the company offers ... outfits. All these fashionable products are offered at promotional ...
(Date:8/20/2014)... 21, 2014 Top10BestSEOHosting.com is a ... about hosting products. It is headed by a ... The site offers research-based information and factual studies ... in the current market. , Recently, Top10BestSEOHosting.com ... that GoDaddy and Bluehost are the ...
(Date:8/20/2014)... 2014 The International Board ... an organization recognizing professionals dedicated to promoting quality ... that with a certificate in autism , ... the Autism Spectrum have a way to show ... This, in turn, say IBCCES representatives, increases the ...
(Date:8/20/2014)... Tampa, FL (PRWEB) August 20, 2014 Locating ... for users of the Quotes Pros website. A new source ... adults price and review rates good for all 50 states ... now configured is one of the new methods available for ... different insurer packages that are supplied. The instant quotations that ...
Breaking Medicine News(10 mins):Health News:Medical Alert Systems Website Now Offering Special Prices on the Popular Medical Guardian Product 2Health News:Medical Alert Systems Website Now Offering Special Prices on the Popular Medical Guardian Product 3Health News:Angeldress.co.uk Now Dazzles With Beautiful Summer Cocktail Party Dresses 2Health News:New Reviews For Linux Web Hosting Suppliers Announced By Top10BestSEOHosting.com 2Health News:National Autism Certificate Credentialing Board IBCCES Increases Job Placement Opportunities for Those Dedicated to Working Within the Autism Spectrum 2Health News:National Autism Certificate Credentialing Board IBCCES Increases Job Placement Opportunities for Those Dedicated to Working Within the Autism Spectrum 3Health News:Term Life Insurance Price Database Now Helps Quote Prices for Adults in 50 States Online 2
... survey conducted by Synovate India and sponsored by Colgate-Palmolive (India) ... and the latest toothpaste available in the market, //the level ... of those surveyed admitted that they have never been to ... that poor oral hygiene practices are resulting in a myriad ...
... more than 5.13 million patients are suffering from AIDS ... being reported each year. Anti-retroviral treatments //have already been ... ,The priority of the Indian Government is to save ... Inorder to increase awareness and promote community participation, of ...
... his research team from Kyoto University have found that daily ... The results of the study have been published in the ... conducted in 387 healthy volunteers between the age group of ... into three groups, the first group gargled water with povidone-iodine, ...
... growing number of animal and human studies show that ... pain sensitivity, resulting in hyperalgesia (abnormally intense pain in ... in response to non-painful stimulation). , ... previous studies have found evidence for hyperalgesia only subsequent ...
... findings released by University of Florida doctors claim that some ... radiation therapy if they undergo a CT scan.// This scan ... the researchers claim. ,These findings were presented at ... and Oncology. Stanley L. Liauw, M.D., a resident in radiation ...
... was first initiated in India to help overcome Vitamin ... in India, it now lags behind African and neighbouring ... report.,The report entitled "Controlling Vitamin and Mineral Deficiencies in ... the largest percentage as well as the largest absolute ...
Cached Medicine News:Health News:Condom Vending Machines To Be Installed Across Indian States 2Health News:Daily Gargling May Prevent Common Colds 2Health News:Opioids And Abnormal Pain Perception 2Health News:Vitamin A supplementation inadequate in India: Need for effective strategies 2
(Date:8/20/2014)... New York , August 20, 2014 ... a new market report titled "Monochloroacetic Acid (MCA) Market ... Applications - Global Industry Analysis, Size, Share, Growth, Trends ... market was valued at USD 817.1 million in 2013 ... 2020, growing at a CAGR of 3.6% during the ...
(Date:8/20/2014)... , Aug. 20, 2014   Ventana Medical ...  Group, today announced that its VENTANA System for ... in the European Union for routine pathology, including ... consisting of VENTANA Virtuoso software coupled with either ... HT slide scanner, provides automated digital slide creation, ...
(Date:8/20/2014)... , Aug. 20, 2014  Amerigen Pharmaceuticals Ltd. announces ... Ltd., has received Chinese FDA (CFDA) approval and ... Tablets into the China ... and distribution agreement with Sinochem Jiangsu Pharmaceutical Co., ... US FDA approved and China CFDA certified oral ...
Breaking Medicine Technology:Global Monochloroacetic Acid (MCA) Market is Expected to Reach USD 1,046.7 million by 2020: Transparency Market Research 2Global Monochloroacetic Acid (MCA) Market is Expected to Reach USD 1,046.7 million by 2020: Transparency Market Research 3Global Monochloroacetic Acid (MCA) Market is Expected to Reach USD 1,046.7 million by 2020: Transparency Market Research 4Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 2Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 3Amerigen Pharmaceuticals Ltd. announces that its Chinese subsidiary, Suzhou Amerigen Pharmaceuticals Co. Ltd., has received Chinese FDA (CFDA) approval and has subsequently launched its generic Mecobalamin 0.5 mg Tablets into the China domestic mark 2
... RIDGEFIELD, Conn., Sept. 8 The country,s newest ... added the largest association of respiratory therapists - ... to its ranks.  The AARC joins DRIVE4COPD, the ... organizations the American Lung Association, COPD Foundation and ...
... (OTCQB: CGCP) today announced that the Wall Street ... McCormick.  The interview includes a discussion of the ... including an approximate 17% year-over-year increase in disposable ... and an overview of the company and its ...
Cached Medicine Technology:American Association for Respiratory Care (AARC) Joins DRIVE4COPD to Raise Awareness of Nation's 4th Leading Cause of Death 2American Association for Respiratory Care (AARC) Joins DRIVE4COPD to Raise Awareness of Nation's 4th Leading Cause of Death 3American Association for Respiratory Care (AARC) Joins DRIVE4COPD to Raise Awareness of Nation's 4th Leading Cause of Death 4American Association for Respiratory Care (AARC) Joins DRIVE4COPD to Raise Awareness of Nation's 4th Leading Cause of Death 5Cardiogenesis Executive Chairman Paul J. McCormick Updates Commercial and Regulatory Progress in Interview With Wall Street Reporter, Available Online 2Cardiogenesis Executive Chairman Paul J. McCormick Updates Commercial and Regulatory Progress in Interview With Wall Street Reporter, Available Online 3
... concave seats and standard-sized backrests with ... seats, backrests, armrests, and casters and ... for the following environments: industry, education, ... care and office. • With reinforced ...
... concave seats and standard-sized backrests with ... seats, backrests, armrests, and casters and ... for the following environments: industry, education, ... care and office. • With reinforced ...
... chairs with concave seats and standard-sized ... options like seats, backrests, armrests, and ... are recommended for the following environments: ... control, health care and office. • ...
... with concave seats and standard-sized backrests ... like seats, backrests, armrests, and casters ... recommended for the following environments: industry, ... health care and office. • With ...
Medicine Products: