Navigation Links
Perforomist Inhalation Solution data to be presented today at American Thoracic Society conference
Date:5/19/2009

dyspnea and rescue medication use were seen over tiotropium treatment alone, without any additional safety or tolerability issues.

Efficacy was measured by serial spirometry, transitional dyspnea index (TDI), rescue albuterol use and the St. George's Respiratory Questionnaire (SGRQ).

The primary efficacy endpoint was standardized absolute FEV1 AUC0-3. At Week 6 the primary efficacy endpoint was significantly improved by 192 mL compared with placebo/tiotropium (1.54 versus 1.37 L, p<0.0001). Following treatment, the mean TDI score showed a significant and clinically meaningful improvement in dyspnea in the Perforomist Inhalation Solution/tiotropium group compared with the placebo/tiotropium group, with mean TDI scores of 1.97 and 0.67, respectively (p=0.0001).

When Perforomist Inhalation Solution was added to tiotropium there was a significant decrease in the need for rescue albuterol use throughout the double-blind period compared with placebo/tiotropium (p<0.0001). SGRQ scores were similar both between treatments and to baseline, except the symptom domain score, which fell in the Perforomist Inhalation Solution/tiotropium group (-5.8) compared with placebo/tiotropium group (-1.0).

Overall, 31 percent of Perforomist Inhalation Solution/tiotropium-treated subjects experienced adverse events versus 46 percent of the placebo/tiotropium-treated subjects. COPD exacerbations were the most common adverse events, and occurred in over twice as many placebo/tiotropium-treated subjects as Perforomist Inhalation Solution/tiotropium-treated subjects. The most frequent adverse events following COPD exacerbations were acute bronchitis and upper respiratory tract infections.

"COPD patients in this analysis saw improvement in several areas when adding Perforomist Inhalation Solution to their tiotropium treatment," said Davida J. White Pettaway, M.D., Senior Manager, Medical and Scientific Affairs, Dey, L.P. "Having replicate
'/>"/>

Contact: Julie Piszczor
jpiszczor@powelltate.com
202-585-2106
Powell Tate
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Clinical Trial Data for Perforomist(TM) Inhalation Solution to be Presented at ATS on May 20, 2008
2. Perforomist-comparable pharmacokinetic and pharmacodynamic profile to DPI formulation
3. Concomitant use of Perforomist & tiotropium -- significant improvements -- COPD
4. U.S. Patent and Trademark Office Issues Mylans Specialty Division, Dey L.P., Three Additional Patents Protecting Perforomist(R) Inhalation Solution
5. Dey, L.P. Highlights Perforomist(R) Inhalation Solution Data to Be Presented at the International Conference of the American Thoracic Society
6. Perforomist Inhalation Solution data to be presented at American Thoracic Society conference
7. Perforomist(R) Inhalation Solution Data in Patients With Moderate to Severe COPD to Be Presented at the International Conference of the American Thoracic Society
8. FDA Approves ASMANEX (R) TWISTHALER(R) (Mometasone Furoate Inhalation Powder) for the Once Daily Maintenance Treatment of Asthma in Children Ages 4-11
9. Par Pharmaceutical Begins Shipment of Budesonide Inhalation Suspension Immediately
10. Sentillion Introduces Affordable Next Generation Healthcare Single Sign-On Solution Called expreSSO(TM)
11. Ken Sperling to Lead CIGNA HealthCare Retiree Solutions Unit
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2014)... (PRWEB) August 23, 2014 "When men ... comes into contact with the dirty water inside the ... seat itself," said one of two inventors from Naugatuck, ... germs, we developed this protective device." , They developed ... toilet surfaces, including the water, bowl and seat. This ...
(Date:8/23/2014)... New York, New York (PRWEB) August 23, 2014 ... ( http://www.consumerinjurylawyers.com/wright-conserve-hip-replacement.html ) filed on behalf of ... in the Conserve hip replacement line continue to ... District of Georgia, Bernstein Liebhard LLP reports. According ... has established a bellwether trial program that would ...
(Date:8/23/2014)... NY (PRWEB) August 23, 2014 On ... reported on a data breach suffered by Community ... saw the compromise of 4.5 million records containing Personally ... security numbers. According to Mandiant, who was engaged to ... from an advanced group of cyber attackers based ...
(Date:8/23/2014)... (PRWEB) August 23, 2014 The MPWMD Board ... use of AWGs as a sole source of water for ... assistance of local architect, Ron Brown of Archworks, LLC in ... this is the first time a water district in the ... an alternative water source. AWGs at this time can ...
(Date:8/23/2014)... August 23, 2014 Pixel Film Studios, a ... today the release of ProIntro Vol.3, a customizable title ... and professional tile just by dragging ProIntro Vol.3 in their ... Vol.3 is a definite time saver and i think our ... with 30 beautifully designed titles made with Final Cut Pro ...
Breaking Medicine News(10 mins):Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 2Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 3Health News:Wright Conserve Hip Lawsuits Move Forward, as Federal Court Issues Order Pertaining to Bellwether Trials, Bernstein Liebhard LLP Reports 4Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 2Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 3Health News:This Time Prominent Hospital Group Falls Prey to Hackers Believed to be Based in China 4Health News:Historical Moment in the Monterey Peninsula, Brings Drought Relief Solution to California, with the Help of EcoloBlue and AWG Technology 2Health News:A new plugin was announced today, ProIntro Vol.3 from Pixel Film Studios for Final Cut Pro X 2
... had found the strains of bird flu disease in the ... time the disease of avian influenza had been detected in ... with the domestic poultry, or waterfowl., ,The team of ... hundreds of wild birds, both live and dead including, that ...
... Tamil Nadu AIDS Initiative (TAI) will soon begin training ... The move has been accelerated following the provision of ... five years. //, ,The decision to train sex ... up after the representatives of sex workers recommended that ...
... combination vaccine for diphtheria, tetanus, pertussis and hepatitis-B ... four life threatening diseases. // , ,Shantha ... has manufactured and marketed the product keeping in ... combination vaccines., ,The new combination vaccine serves ...
... fact, it's almost taken on epidemic-like proportions, with city ... patients suffering from microbial infections. //, ,Doctors warn ... diseases like hepatitis E, meningitis, typhoid and malaria. Since ... by oro-nasal routes and through people-to-people contact usually have ...
... a holistic medical system developed two centuries ago by ... an effective healing method though conventional medicine still views ... formulated the principles of homeopathy on the idea of ... that Peruvian or China bark was prescribed to combat ...
... newborns for permanent childhood hearing impairment (PCHI) might help ... condition by about 43%. The study findings were presented ... is a congenital defect that affects 112 per 100,000 ... disputed for this condition but preliminary evidence suggests that ...
Cached Medicine News:Health News:Bird Flu Strains Detected In Wild Birds Of Mongolia 2Health News:Sharp Increase Of The Deadly Diseases In Delhi 2Health News:Popularity Of Homeopathy On The Increase 2Health News:Popularity Of Homeopathy On The Increase 3
(Date:8/22/2014)... , Aug. 22, 2014 MC Medical, a ... (MID), a Columbus, OH medical device ... the FloShield laparoscopic and robotic visualization system in ... approved for sale in Japan in ... long-time experience and an extensive product portfolio in endoscopic surgery ...
(Date:8/22/2014)...  Mark Riccio, director of Cornell University,s multi-scale ... the online crowd-funding platform Kickstarter to bring non-invasive ... and would-be superheros everywhere: "for FREE." Riccio,s campaign, ... if you had Superman,s X-ray vision?" The campaign ... from elementary through high school students, academic institutions, ...
(Date:8/22/2014)... 2014  WaferGen Bio-systems, Inc. (NASDAQ: WGBS) today announced ... of common stock and warrants at a price of ... prior to deducting underwriting discounts and commissions and offering ... are immediately separable and will be issued separately.  The ... on The NASDAQ Stock Market under the ticker symbol ...
Breaking Medicine Technology:MC Medical agrees to be the exclusive distributor of FloShield products in Japan 2Cornell's X-ray Imaging Lab Director Uses Kickstarter Campaign to "Democratize" Advanced 3D Imaging 2WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 2WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 3WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 4
... Musculoskeletal Transplant Foundation (MTF) has announced the release of two ... The new sizes--16cm x 20cm and 20cm x 20cm--are being ... their patients. This unique human dermal allograft is specifically prepared ... has been a year since MTF introduced its bi-lateral breast ...
... -- Lotus Pharmaceuticals, Inc. (OTCBB: LTUS) ("Lotus" or the ... and drugs in the People,s Republic of China ("PRC"), ... its Inner Mongolia branch company, including land use right ... Inner Mongolia, in order to focus its business on ...
Cached Medicine Technology:New, Larger, Bilateral Breast Graft Kits Announced by MTF 2Lotus Pharmaceuticals Announces Business Reorganization and Provides Updates on the Beijing Headquarters Building 2Lotus Pharmaceuticals Announces Business Reorganization and Provides Updates on the Beijing Headquarters Building 3
... Neuro-Patch is a non-absorbable ... highly purified polyesterurethane. Its ... proliferation of fibroblast, supporting ... "weave" minimizes suture channels, ...
The Bovie IDS Series are the latest electrosurgical generators with fully digital implementation....
Aaron 2250 is a multipurpose electrosurgical generator with monoploar and bi-polar functions....
Adson bipolar forceps, 12 cm, straight....
Medicine Products: