Navigation Links
People with low risk for cocaine dependence have differently shaped brain to those with addiction
Date:1/17/2013

People who take cocaine over many years without becoming addicted have a brain structure which is significantly different from those individuals who developed cocaine-dependence, researchers have discovered. New research from the University of Cambridge has found that recreational drug users who have not developed a dependence have an abnormally large frontal lobe, the section of the brain implicated in self-control. Their research was published in the journal Biological Psychiatry.

For the study, led by Dr Karen Ersche, individuals who use cocaine on a regular basis underwent a brain scan and completed a series of personality tests. The majority of the cocaine users were addicted to the drug but some were not (despite having used it for several years).

The scientists discovered that a region in the frontal lobes of the brain, known to be critically implicated in decision-making and self-control, was abnormally bigger in the recreational cocaine users. The Cambridge researchers suggest that this abnormal increase in grey matter volume, which they believe predates drug use, might reflect resilience to the effects of cocaine, and even possibly helps these recreational cocaine users to exert self-control and to make advantageous decisions which minimize the risk of them becoming addicted.

They found that this same region in the frontal lobes of the brain was significantly reduced in size in people with cocaine dependence, confirming earlier research that had found similar results. They believe that at least some of these changes are the result of drug use, which causes drug users to lose grey matter.

They also found that people who use illicit drugs like cocaine exhibit high levels of sensation-seeking personality traits, but only those developing dependence show personality traits of impulsivity and compulsivity.

Dr Ersche, of the Behavioural and Clinical Neuroscience Institute (BCNI) at the University of Cambridge, said: "These findings are important because they show that the use of cocaine does not inevitably lead to addiction in people with good self-control and no familial risk.

"Our findings indicate that preventative strategies might be more effective if they were tailored more closely to those individuals at risk according to their personality profile and brain structure."

The researchers will next explore the basis of the recreational users' apparent resilience to drug dependence.

Dr Ersche added: "Their high level of education, less troubled family background or the beginning of drug-taking only after puberty may all play a role."


'/>"/>

Contact: Genevieve Maul
gm349@admin.cam.ac.uk
44-012-237-65542
University of Cambridge
Source:Eurekalert

Related medicine news :

1. Diet Plan To Lose Weight
2. How “The Healthy Way Diet” Can Help People Burn Fat Naturally – Health Review Center
3. Mayo Clinic: Skin problems, joint disorders top list of reasons people visit doctors
4. Dr. Sam Speron Tips On How People Can Spot Breast Implants
5. Many People Underestimate How Long a Cough Should Last
6. Burn Fat Fast
7. How "30 Days To Thin" Helps People Melt Fat Naturally and Effectively - Tony Nguyen
8. Increase Height Naturally
9. Can “Grow Taller 4 Idiots” Help People Boost Their Height Effectively – Health Review Center
10. Haiti can quell cholera without vaccinating most people, UF researchers estimate
11. Philadelphia Malpractice Lawyers at Console & Hollawell Explore Negligence as Overdoses from Prescription Painkillers Now Kill More People than Heroin
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/21/2017)... ... July 21, 2017 , ... West Dermatology is pleased to announce the ... July 17, 2017, Ms. Vu will join West Dermatology’s large network of medical and ... skin cancer , and more. She graduated from the University of Florida College ...
(Date:7/21/2017)... ... July 21, 2017 , ... ... concussion rates are on the rise, say researchers presenting their work at the ... Ontario, Canada. , “The combination of evaluating the patterns of change in concussion ...
(Date:7/20/2017)... ... July 20, 2017 , ... Acute myeloid leukemia ... that progresses rapidly without treatment. Newly diagnosed patients face intense chemotherapy regimens and ... and relapse. With such a challenging diagnosis that requires immediate action, patients ...
(Date:7/20/2017)... ... ... For individuals with extended hospital stays or who are residents of nursing homes, ... designed to accommodate patients with a wide range of ailments or special needs, but ... invented the patent-pending PORTABLE ARM REST, a specially designed armrest that features many uses, ...
(Date:7/20/2017)... , ... July 20, 2017 , ... Doctors on Liens, ... addition of Horine Chiropractic , directed by Dr. Russell Horine, DC to their ... completely family run with Dr. Russell Horine serving as the clinic director and his ...
Breaking Medicine News(10 mins):
(Date:7/11/2017)... July 11, 2017  Sysmex America, Inc., a ... testing equipment as well as middleware information systems ... to make quality assurance easier and more risk ... well known for the innovation that it delivers ... elevates quality assurance processes to a new level ...
(Date:7/11/2017)... JERUSALEM , July 11, 2017 Oramed ... ), a clinical-stage pharmaceutical company focused on the development ... U.S. Food and Drug Administration (FDA) has agreed to ... successfully completed Phase IIb trial of its oral insulin ... The Phase IIb trial met primary and secondary endpoints ...
(Date:7/10/2017)... , July 10, 2017 The Institute for ... methods, is the recipient of a VITROCELL® inhalation exposure ... International Science Consortium. The device, which is designed to ... expose human lung cells to airborne test materials in ... use the VITROCELL® system for testing combustible tobacco products, ...
Breaking Medicine Technology: