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People with diabetes are at higher risk of atrial fibrillation
Date:4/22/2010

iabetes.

"When a patient with diabetes has symptoms like heart palpitations, clinicians should have a higher level of suspicion that the reason could be atrial fibrillation," Dr. Dublin said. "This heart rhythm disturbance is important to diagnose, because it can be treated with medications like warfarin that can prevent many of the strokes that the atrial fibrillation would otherwise cause."

It is hard to establish which comes firstdiabetes or atrial fibrillationwith this kind of case-control study, unlike a randomized trial, Dr. Dublin said. "But our finding that the risk of atrial fibrillation is higher with longer time since patients started medications for diabetes, and with higher blood glucose levels, is strongly suggestive that diabetes can cause atrial fibrillation." She used time since starting diabetes medication as a measure of how long patients had the disease.

Dr. Dublin's work was funded through a Veterans' Affairs Health Services Research & Development fellowship and a Paul Beeson Career Development Award from the National Institute on Aging. The Beeson Award is also supported in part by the American Federation for Aging Research, the Hartford Foundation, the Atlantic Philanthropies and the Starr Foundation. The National Heart, Lung, and Blood Institute funds the Heart and Vascular Health Study, which collects data on Group Health patients newly diagnosed with atrial fibrillation and other cardiovascular conditions. The study of atrial fibrillation, led by Dr. Dublin's co-author Dr. Susan Heckbert, aims to find new factors that raise the risk of developing this quivering of the heart's upper chambers (atria).

About one in 100 peopleand nearly nine in 100 people over age 80have atrial fibrillation, according to Dr. Heckbert, a professor of epidemiology and scientific investigator in the Cardiovascular Health Research Unit at the University of Washington (UW) and an affiliate investigator at Group Health Re
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Contact: Joan DeClaire
declaire.j@ghc.org
206-287-2653
Group Health Research Institute
Source:Eurekalert

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