Navigation Links
Penn's Abramson Cancer Center part of major phase III study for myeloma
Date:11/21/2007

PHILADELPHIA Researchers from the Abramson Cancer Center of the University of Pennsylvania announced today that findings from two large, international clinical trials show unprecedented survival for patients with multiple myeloma, a cancer that occurs in the blood-making cells of bone marrow. The findings show that with the oral drug lenalidomide (REVLIMID), in combination with the steroid dexamethasone, patients significantly improved by all measures where previous treatments had failed including a median survival of nearly three years the longest median survival known for this difficult to treat patient group. Edward A. Stadtmauer, MD, Director of the Abramson Cancer Center Bone Marrow and Stem Cell Transplant Program and lead investigator from Penn, was part of the U.S. study published today in the New England Journal of Medicine alongside a companion study from Europe showing similar results.

"Myeloma, also known as multiple myeloma, is a growing interest and concern of cancer clinicians and researchers," said Stadtmauer. "While most U.S. cancer diagnoses are decreasing, statistics show that the number of myeloma diagnoses is increasing, particularly in younger patients. This disturbing trend fuels the urgency to discover effective treatments to fight this disease. This study shows that this new class of drugs is a critical advance toward meeting that need."

REVLIMID (lenalidomide) from Celgene, an oral medication which treats without the ravages of chemotherapy, is the first in a new class of medications called immunomodulatory drugs (IMiDs). It works by attacking both the cancer cell and the micro-environment in which it lives in the bone marrow, thereby stopping the cells ability to adhere to the wall of tissues where they will grow. REVLIMID may also inhibit cancer cells ability to hide from the bodys natural killer cells in the immune system by stopping angiogenesis the growth of blood vessels that penetrate into and feed cancero
'/>"/>

Contact: Olivia Fermano
Olivia.Fermano@uphs.upenn.edu
215-349-5653
University of Pennsylvania School of Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Governor Rendell Offers adultBasic Coverage to 35,000 Uninsured Pennsylvanians
2. Health and Business Groups Launch Ad Campaign About Need for Comprehensive Smoke-Free Law in Pennsylvania
3. NNN Healthcare/Office REIT Acquires 2750 Monroe Boulevard in Valley Forge, Pennsylvania
4. Pennsylvania Department of Aging Receives Grant to Improve Alzheimers Support
5. Pennsylvania Needs More Lung Cancer Research
6. Saint Vincent Health System of Erie, Pennsylvania Named One of AARP 2007 Best Employers for Workers Over 50
7. Pennsylvania Game Commission Announces EHD Confirmed in Allegheny and Westmoreland Counties
8. Maryland, Minnesota Go Smoke-free Oct. 1 - Pennsylvania Overdue in Following Suit
9. Pennsylvania Trauma Systems Foundation Accreditation Status for Trauma Centers
10. Health Secretary Urges Pennsylvanians to Get a Flu Shot
11. Governor Rendell Calls for Prompt Action on Prescription for Pennsylvania, Cover All Pennsylvanians Health Care Reforms
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... 19, 2014 (HealthDay News) -- The U.S. Food and Drug ... Thursday. Trulicity is part of a class of once-a-week injectable ... type 2 diabetes. "Trulicity is a new treatment ... treatment regimens to control blood sugar levels in the overall ... of the FDA,s Office of Drug Evaluation II, said in ...
(Date:9/19/2014)... The Alliance for Bangladesh Worker Safety ... Fire Protection Association (NFPA), a recognized international leader ... a Memorandum of Understanding signed by both organizations, ... stakeholders with information, guidance and access to training ... safety of workers in ready-made garment (RMG) factories ...
(Date:9/19/2014)... MetroMD, a leading anti-ageing clinic has called its ... health. This therapy has grown tremendously across USA in the ... safe and dependable. It has far reaching benefits for ageing ... a very healthy and active lifestyle even beyond their middle ... senior therapist at MetroMD said, “HGH or Human Growth hormones ...
(Date:9/19/2014)... September 19, 2014 "I have difficulty ... wrinkles due to stretching the skin around my eyes ... "This inspired me to design a more convenient method ... LENS SYSTEM provides a quicker, easier, more sanitary method ... to perform this task manually, saves time and effort, ...
(Date:9/19/2014)... - New research published today in the online journal ... reach 6,800 in West Africa by the end of ... , Arizona State University and Harvard University researchers ... rise in cases significantly increased in August in Liberia ... was put in place, indicating that the mass quarantine ...
Breaking Medicine News(10 mins):Health News:FDA Approves Another Weekly Injectable Drug for Type 2 Diabetes 2Health News:Alliance for Bangladesh Worker Safety and NFPA Sign Memorandum of Understanding to Strengthen Safety in Bangladesh Garment Factories 2Health News:Alliance for Bangladesh Worker Safety and NFPA Sign Memorandum of Understanding to Strengthen Safety in Bangladesh Garment Factories 3Health News:MetroMD Announces Better HGH Therapy - the ‘God Particle’ of Human Health 2Health News:Research predicts possible 6,800 new Ebola cases this month 2
... North Carolina in Chapel Hill that was published in the ... two genes - C282Y and H63D, which are linked to ... increased risk of developing colon cancer. For the research, the ... which, more than 400 already had colon cancer, and were ...
... at Trinity College, Dublin, Ireland, have found from a ... arterial stiffness after smoking even one cigarette in both ... effects of smoking on large artery properties in 185 ... years. 116 non-smokers// were compared with 41 chronic smokers ...
... have traditionally been treated by removing a disc or placing ... together. Now, an artificial disc which is being studied as ... phase one study that was recently completed compared the prosthesis ... patients// were randomized, with one having a fusion operation for ...
... is being reassessed to find out if it could again ... and leprosy. The drug which is unlicensed in Europe was ... morning// sickness. However, it was banned after mothers who took ... for the Evaluation of Medicinal Products (EMEA) is now considering ...
... among children that were known until now were chickenpox, ... neurologists have found that stroke is also among one ... go unnoticed. A National Hospital's database analysis by Dr. ... California showed that four in 1000 newborns had a ...
... recent health survey across England showed that many do ... cancer and other serious diseases. The survey included nearly// ... trends were revealed by the study. ,The survey ... eating and household income. Almost 40% of women in ...
Cached Medicine News:Health News:Artificial discs available as replacements for damaged discs 2Health News:Stroke also in list of common childhood ailments 2
(Date:9/19/2014)... TRIANGLE PARK, N.C. , Sept. 19, 2014 ... focused on cloud-based drug design and development, partnering ... The company,s mission is to design new drugs ... 1 and 2 partners to further their development. ... its portfolio investments. To support this business model, ...
(Date:9/19/2014)... Sept. 19, 2014  Diplomat, the nation,s largest independent ... Dreyer to the Board of Directors on September ... will also serve as chair of the Audit Committee. ... of accounting, financial, compliance and operating experience in the ... served as chief financial officer, chief operating officer and ...
(Date:9/19/2014)... WALTHAM, Mass. , Sept. 19, 2014  Alere ... in rapid diagnostics, issued the following statement today in ... Combating Antibiotic-Resistant Bacteria. "As the global leader ... President for establishing a national strategy to address the ... continuing to work with the Administration on initiatives to ...
Breaking Medicine Technology:Cloud Pharmaceuticals Announces Partnering Sessions and Presentation Schedule 2David Dreyer Appointed to Diplomat Board of Directors 2Alere Applauds President's Executive Order Combating Antibiotic-Resistant Bacteria 2
... Oct. 12 Ethicon Endo-Surgery, Inc., today ... at the 95th Annual Clinical Congress of the ... technologies of worldwide leading HARMONIC® ultrasonic and ENSEAL® ... delivery options that provide superior energy application for ...
... 12 Stereotaxis, Inc. (Nasdaq: STXS ) announced today ... Stereotaxis common stock have exercised in full their over-allotment option ... stock. The 7,475,000 shares of Stereotaxis common stock in ... option, are being sold at a price to the public ...
Cached Medicine Technology:Ethicon Endo-Surgery Unveils Full Energy Portfolio for First Time at American College of Surgeons Clinical Congress 2Ethicon Endo-Surgery Unveils Full Energy Portfolio for First Time at American College of Surgeons Clinical Congress 3Stereotaxis Announces Underwriters' Exercise of Over-Allotment Option 2Stereotaxis Announces Underwriters' Exercise of Over-Allotment Option 3
... Bird and Cronin, Inc. ... of Patient Footwear, Orthopedic ... Care Products. Our products ... quality and available in ...
... Splint uses safe, mild to moderate force ... at the MP joints. Dorsal-based splint does ... ulnar polycentric hinges located at the MP ... malleable finger rings can be individually shaped ...
... constructed of a durable heat moldable thermoplastic for ... of the hand and fingers from stress following ... later stages of the healing process. , ... positions the wrist at 30° of flexion, the ...
Bunell Mini-Modified Safety Finger Pin reduces PIP flexion contractures....
Medicine Products: