Navigation Links
Penn talks at ASCB touch on cancer, neurodegenerative diseases, and MD

WASHINGTON, DC Among the 72 posters, lectures, and mini-symposia given by University of Pennsylvania researchers at the ASCB annual meeting are talks that present new research findings on the molecular workings of several types of diseases.

The 47th annual meeting of the American Society of Cell Biology takes place on December 1-5, 2007 in Washington, D.C.

Some highlights are:

  • Huntington's Disease: A new role has been discovered for huntingtin (Htt), the defective protein in Huntington's Disease. Htt is crucial for the movement of packets inside cells that recycle and transport important molecules. Disruption of this movement by mutant Htt may help explain the nerve degeneration seen in Huntington's disease. These findings are presented by J. P. Caviston and E. L. F. Holzbaur of the Department of Physiology. (#2091, Poster 12/4)

  • Lou Gehrig's Disease (ALS): Nerve degeneration diseases such as ALS may be caused by disruption of molecular signaling, a normal process that involves transport of critical signal molecules from the nerve synapse into the nerve cell body. The study was conducted by E. Perlson, J. Ross, K. Wallace, R. Dixit, G. Jeong, R. Kalb, and E. L. Holzbaur of the Department of Physiology. (#1659, Poster, 12/4)

  • Muscular Dystrophies (MD): Some MDs are caused by the failure of muscle cells to adhere to a structural scaffold so that they can withstand cell-generated tension. Paxillin, a protein that is more abundant in some muscular dystrophies, may cause the dystrophic cells to be overly tense. This study was conducted by M. Tewari, S. Sen, A. Engler, M. Zad, and D. E. Discher of the School of Arts and Sciences, P. Acousta and H. L. Sweeney of the Pennsylvania Muscle Institute and Department of Physiology, and E. Barton of the Dental School. (#1389, Poster, 12/3)

  • Cancer: An enzyme required for normal growth and development, called ATE1, may be a tumor suppressor. Cells from mice that had the ATE1 gene knocked out were able to cause tumors when transplanted into normal mice. This finding is presented by R. R. Rai and A. Kashina of the Animal Biology Department. (#1533, Poster, 12/3)

  • Cancer: A protein called Rap1 is involved in tumor cell migration. It is located in cell motile feet, and is over-expressed in surgical specimens of infiltrating cancers of the breast. This study was conducted by W. S. Y. Lee and N. Kushnir of the Department of Microbiology, D. K. Furstenau and M. J. L. Dela Cruz of the Department of Surgery, and M. A. Guvakova of both departments. (#398, Poster, 12/2)


Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Related medicine news :

1. Barbershop Talks Cut Black Mens Prostate Cancer Risk
2. Actor Joe Pantoliano Discloses Depression; Talks About His Latest Movie and His Sensitive Side
3. Broadband Wireless International Corporation Announces the Commencement of Good Faith Talks with HealthPitch
4. Elite Athlete Podiatrist Talks About the G-Trainer at New York Athletic Club
5. Women of Philadelphia Win by a Touchdown
6. NFL-Themed Milk Touches Down in Schools and Retail Grocery Stores
7. L.A. Playwright Creates an Enormous Wave with His New Book, Touch the Ocean
8. Scientists identify brain circuits used in sensation of touch
9. Avocados may help prevent oral cancer, OSU study shows
10. Studies Shed New Light on Breast Cancer, Treatment
11. Blood protein detects lung cancer, even at earliest stage
Post Your Comments:
(Date:11/27/2015)... ... ... A team of Swiss doctors has released a report on mesothelioma relapse ... the findings on the website. Click here to read the details now. ... who were treated with chemotherapy followed by EPP surgery. Among the 106 patients who ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... the November 27th edition of USA Today in Atlanta, Dallas, New York, Minneapolis, ... of 750,000. The digital component is distributed nationally, through a vast social media ...
(Date:11/27/2015)... , ... November 27, 2015 , ... ... the well-respected Microsoft Dynamics SL User Group (MSDSLUG). Recognized as Microsoft’s official group ... group of Microsoft Dynamics SL software users, partners, industry experts and representatives. Intellitec ...
(Date:11/27/2015)... ... November 27, 2015 , ... CBD College is proud to ... Programs (CAAHEP) awarded accreditation to its Diagnostic Medical Sonography program. CBD College is honored ... one of twelve colleges and universities in the state of California make the cut. ...
(Date:11/27/2015)... ... November 27, 2015 , ... Indosoft ... announces the incorporation of Asterisk 11 LTS (Long Term Support) into its Q-Suite ... LTS brings Q-Suite 5.10 up-to-date with a version of Asterisk that will receive ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... November 26, 2015 ... the "2016 Future Horizons and Growth ... Testing Market: Supplier Shares, Country Segment Forecasts, ... their offering. --> ) ... "2016 Future Horizons and Growth Strategies in ...
(Date:11/26/2015)... 2015 ... the  "2016 Future Horizons and Growth ... Monitoring (TDM) Market: Supplier Shares, Country ...  report to their offering.  --> ... addition of the  "2016 Future Horizons ...
(Date:11/26/2015)... DUBLIN , November 26, 2015 ... has announced the addition of the  ... in the European Cell Surface Marker ... Emerging Opportunities"  report to their offering.  ... announced the addition of the  "2016 ...
Breaking Medicine Technology: