Navigation Links
Penn talks at ASCB touch on cancer, neurodegenerative diseases, and MD
Date:12/3/2007

WASHINGTON, DC Among the 72 posters, lectures, and mini-symposia given by University of Pennsylvania researchers at the ASCB annual meeting are talks that present new research findings on the molecular workings of several types of diseases.

The 47th annual meeting of the American Society of Cell Biology takes place on December 1-5, 2007 in Washington, D.C.

Some highlights are:

  • Huntington's Disease: A new role has been discovered for huntingtin (Htt), the defective protein in Huntington's Disease. Htt is crucial for the movement of packets inside cells that recycle and transport important molecules. Disruption of this movement by mutant Htt may help explain the nerve degeneration seen in Huntington's disease. These findings are presented by J. P. Caviston and E. L. F. Holzbaur of the Department of Physiology. (#2091, Poster 12/4)

  • Lou Gehrig's Disease (ALS): Nerve degeneration diseases such as ALS may be caused by disruption of molecular signaling, a normal process that involves transport of critical signal molecules from the nerve synapse into the nerve cell body. The study was conducted by E. Perlson, J. Ross, K. Wallace, R. Dixit, G. Jeong, R. Kalb, and E. L. Holzbaur of the Department of Physiology. (#1659, Poster, 12/4)

  • Muscular Dystrophies (MD): Some MDs are caused by the failure of muscle cells to adhere to a structural scaffold so that they can withstand cell-generated tension. Paxillin, a protein that is more abundant in some muscular dystrophies, may cause the dystrophic cells to be overly tense. This study was conducted by M. Tewari, S. Sen, A. Engler, M. Zad, and D. E. Discher of the School of Arts and Sciences, P. Acousta and H. L. Sweeney of the Pennsylvania Muscle Institute and Department of Physiology, and E. Barton of the Dental School. (#1389, Poster, 12/3)

  • Cancer: An enzyme required for normal growth and development, called ATE1, may be a tumor suppressor. Cells from mice that had the ATE1 gene knocked out were able to cause tumors when transplanted into normal mice. This finding is presented by R. R. Rai and A. Kashina of the Animal Biology Department. (#1533, Poster, 12/3)

  • Cancer: A protein called Rap1 is involved in tumor cell migration. It is located in cell motile feet, and is over-expressed in surgical specimens of infiltrating cancers of the breast. This study was conducted by W. S. Y. Lee and N. Kushnir of the Department of Microbiology, D. K. Furstenau and M. J. L. Dela Cruz of the Department of Surgery, and M. A. Guvakova of both departments. (#398, Poster, 12/2)


'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert

0

GOOD

Related medicine news :

1. Barbershop Talks Cut Black Mens Prostate Cancer Risk
2. Actor Joe Pantoliano Discloses Depression; Talks About His Latest Movie and His Sensitive Side
3. Broadband Wireless International Corporation Announces the Commencement of Good Faith Talks with HealthPitch
4. Elite Athlete Podiatrist Talks About the G-Trainer at New York Athletic Club
5. Women of Philadelphia Win by a Touchdown
6. NFL-Themed Milk Touches Down in Schools and Retail Grocery Stores
7. L.A. Playwright Creates an Enormous Wave with His New Book, Touch the Ocean
8. Scientists identify brain circuits used in sensation of touch
9. Avocados may help prevent oral cancer, OSU study shows
10. Studies Shed New Light on Breast Cancer, Treatment
11. Blood protein detects lung cancer, even at earliest stage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2017)... ... September 20, 2017 , ... Compliancy Group is ... software, The Guard®, has helped another long-time client pass their Department of Health ... satisfy the law. , Thanks to the help of the Compliancy Group's Audit ...
(Date:9/20/2017)... ... September 20, 2017 , ... The Centers for Medicare ... Rule that it will transition to using only Worksheet S-10 to distribute Disproportionate Share ... of three live 60-minute complimentary webinars on October 17, 2017 at 2 ...
(Date:9/20/2017)... (PRWEB) , ... September 20, 2017 , ... ... for overcoming addiction. “RECYCLED Ezekiel's Plan for Freedom from ADDICTION” is the ... extensive background in the field of addiction and homeless services, including more than ...
(Date:9/20/2017)... ... ... “The Foggy Road to Moorwick”: the adventures of a young Scottish girl yearning to see ... Liston, a busy mother of five who used her time waiting for children to finish ... over twenty years. It was a way to give some meaning to the hours ...
(Date:9/19/2017)... ... September 19, 2017 , ... Only a few physicians ... include Brevard’s own Ross A. Clevens, MD, FACS . The founder and medical ... Plastic and Reconstructive Surgeon who trained at Yale, Harvard and the University of Michigan. ...
Breaking Medicine News(10 mins):
(Date:9/5/2017)... 2017 Oramed Pharmaceuticals Inc. (NASDAQ: ... pharmaceutical company focused on the development of oral drug ... its meeting with the U.S. Food and Drug Administration ... At the meeting, ... for submission of ORMD-0801, would be a Biologics License ...
(Date:8/31/2017)... PM360,s annual Innovations Issue, published in ... innovations happening across the industry. Established six years ago, ... providing a comprehensive look at the newest and most ... innovative companies, startups, divisions, products, services, and strategies from ... "Everyone in this industry wants to do better—in all ...
(Date:8/28/2017)... Aesculight ®, a division of LightScalpel ®, LLC, is announcing its ... 20 years of American veterinary laser surgery innovation, Aesculight® is revolutionizing veterinary ... ... with his new VetScalpel laser. Dr. Duclos practices veterinary dermatology at the ... ...
Breaking Medicine Technology: