Navigation Links
Penn study suggests professional welders at risk for loss of sense of smell
Date:10/11/2007

PHILADELPHIA Researchers at the University of Pennsylvania School of Medicine have found that professional welders who work in enclosed spaces with poor ventilation may be at risk for loss of sense of smell. The study appears in Neurology.

This is the first study to clearly demonstrate that welders who work in confined spaces without adequate respiratory protection are at risk for damaging their sense of smell, says Richard Doty, PhD, Director, Smell & Taste Center, Professor, Department of Otorhinolaryngology, and senior study author. Although underappreciated, loss of smell function significantly alters quality of life. This important sense not only determines the flavors of foods and beverages, but serves as an early warning system for the detection of fire, dangerous fumes, leaking gas, spoiled foods, and polluted environments.

Using the University of Pennsylvania Smell Identification Test (UPSIT) a self-administered standardized test incorporating 40 scratch-and-sniff odors with multiple choice options to identify the odor the researchers quantitatively evaluated the olfactory function of 43 professional welders who worked in confined spaces on the San Francisco/Oakland Bay Bridge, and compared their test scores with those of matched normal controls.

Dr. Doty and colleagues found that the mean UPSIT scores of the welders were, on average, seven points lower than those of their matched controls (29.62 and 36.90). Thirty eight (88%) performed more poorly than their controls, although only 3 (7%) had a total loss of their sense of smell. The percentages of those with mild, moderate, or severe loss of the sense of smell were 30.2, 18.6, and 16.3. The researchers report that interestingly, of the 42 subjects who provided information regarding their sense of smell before being tested, more than half were unaware of a problem.

Blood tests were administered to test for blood levels of chemicals found in welding fumes. The blood tests revealed that 40.5% of the welders had abnormally elevated levels of manganese (Mn). Although this suggests that the welders were exposed mainly to Mn, it is not entirely clear whether Mn is the basis of their olfactory problems. In fact, the welders with the highest Mn blood levels exhibited better olfactory function than those with the lowest Mn blood levels.

The welders also underwent a neuropsychological test battery. Dr. Doty notes, however, that, The results of this study suggest that exposure to the fumes of welding can alter the ability to smell, and that changes in this important sensory system are not correlated with alterations in cognitive function, which also can be induced by toxins in welding fumes.

The researchers conclude that the basis of the smell loss among the welders is not entirely clear. They suggest that although the research shows that the welders had smell dysfunction in relation to the matched controls, additional groups, such as ones consisting of non-welder industrial workers, might be of value in better defining the causality.


'/>"/>

Contact: Kate Olderman Tavella
kate.olderman@uphs.upenn.edu
215-349-8369
University of Pennsylvania School of Medicine
Source:Eurekalert

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, ... Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments in ... the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in ...
(Date:6/24/2016)... ... ... June 19, 2016 is World Sickle Cell Observance Day. In an effort ... holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a pain ... Disease (SCD) is a disorder of the red blood cells, which can cause episodes ...
(Date:6/24/2016)... ... 24, 2016 , ... Dr. Amanda Cheng, an orthodontist ... has extensive experience with all areas of orthodontics, including robotic Suresmile technology, ... , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It can be used ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine ... Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards honor ... Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With this ...
(Date:6/24/2016)... ... 24, 2016 , ... National recruitment firm Slone Partners is pleased ... and genomics experience, as Vice President of North American Capital Sales at HTG ... leading the sales team in the commercialization of the HTG EdgeSeq system and associated ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Global Blood ... biopharmaceutical company developing novel therapeutics for the treatment ... today announced the closing of its previously announced ... stock, at the public offering price of $18.75 ... offering were offered by GBT. GBT estimates net ...
(Date:6/24/2016)... June 24, 2016 ... announced the addition of the " Global Markets ... This report focuses ... an updated review, including its applications in various applications. ... market, which includes three main industries: pharmaceutical and biotechnology, ...
(Date:6/24/2016)... , June 24, 2016 The Academy ... of recommendations that would allow biopharmaceutical companies ... with entities that make formulary and coverage decisions, a ... "value" of new medicines. The recommendations address ... not appear on the drug label, a prohibition that ...
Breaking Medicine Technology: