Navigation Links
Penn study suggests professional welders at risk for loss of sense of smell
Date:10/11/2007

PHILADELPHIA Researchers at the University of Pennsylvania School of Medicine have found that professional welders who work in enclosed spaces with poor ventilation may be at risk for loss of sense of smell. The study appears in Neurology.

This is the first study to clearly demonstrate that welders who work in confined spaces without adequate respiratory protection are at risk for damaging their sense of smell, says Richard Doty, PhD, Director, Smell & Taste Center, Professor, Department of Otorhinolaryngology, and senior study author. Although underappreciated, loss of smell function significantly alters quality of life. This important sense not only determines the flavors of foods and beverages, but serves as an early warning system for the detection of fire, dangerous fumes, leaking gas, spoiled foods, and polluted environments.

Using the University of Pennsylvania Smell Identification Test (UPSIT) a self-administered standardized test incorporating 40 scratch-and-sniff odors with multiple choice options to identify the odor the researchers quantitatively evaluated the olfactory function of 43 professional welders who worked in confined spaces on the San Francisco/Oakland Bay Bridge, and compared their test scores with those of matched normal controls.

Dr. Doty and colleagues found that the mean UPSIT scores of the welders were, on average, seven points lower than those of their matched controls (29.62 and 36.90). Thirty eight (88%) performed more poorly than their controls, although only 3 (7%) had a total loss of their sense of smell. The percentages of those with mild, moderate, or severe loss of the sense of smell were 30.2, 18.6, and 16.3. The researchers report that interestingly, of the 42 subjects who provided information regarding their sense of smell before being tested, more than half were unaware of a problem.

Blood tests were administered to test for blood levels of chemicals found in welding fumes. The blood tests revealed that 40.5% of the welders had abnormally elevated levels of manganese (Mn). Although this suggests that the welders were exposed mainly to Mn, it is not entirely clear whether Mn is the basis of their olfactory problems. In fact, the welders with the highest Mn blood levels exhibited better olfactory function than those with the lowest Mn blood levels.

The welders also underwent a neuropsychological test battery. Dr. Doty notes, however, that, The results of this study suggest that exposure to the fumes of welding can alter the ability to smell, and that changes in this important sensory system are not correlated with alterations in cognitive function, which also can be induced by toxins in welding fumes.

The researchers conclude that the basis of the smell loss among the welders is not entirely clear. They suggest that although the research shows that the welders had smell dysfunction in relation to the matched controls, additional groups, such as ones consisting of non-welder industrial workers, might be of value in better defining the causality.


'/>"/>

Contact: Kate Olderman Tavella
kate.olderman@uphs.upenn.edu
215-349-8369
University of Pennsylvania School of Medicine
Source:Eurekalert

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/27/2016)... Lafayette, California (PRWEB) , ... ... ... a pioneer in the patient payment industry today announced its strategic partnership ... and health system workflows. , The two companies’ proven, proprietary technology combine ...
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in cancer ... they remain in the eye of the beholder, according to experts who offered insights ... American Journal of Managed Care. For the full issue, click here . , ...
(Date:6/26/2016)... North Carolina (PRWEB) , ... June 26, 2016 , ... ... release of a new product that was developed to enhance the health of felines. ... for centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, ... Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms ... Final Cut Pro X . Simply select a ProHand generator and drag it above ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... , June 23, 2016  MedSource announced today ... its e-clinical software solution of choice.  This latest ... possible value to their clients by offering a ... preferred relationship establishes nowEDC as the EDC platform ... MedSource,s full-service clients.  "nowEDC has long been a ...
(Date:6/23/2016)... Any dentist who has made an implant supported ... Many of them do not even offer this as a ... laboratory costs involved. And those who ARE able to offer ... high cost that the majority of today,s patients would not ... Zadeh , founder of Dental Evolutions Inc. and inventor of ...
(Date:6/23/2016)... startling report released today, National Safety Council research shows ... plan to eliminate prescription opioid overdoses. Prescription Nation ... the worst drug crisis in recorded U.S. history, assigned a "Making ... , New Mexico , Tennessee ... states, three – Michigan , Missouri ...
Breaking Medicine Technology: