Navigation Links
Penn study suggests professional welders at risk for loss of sense of smell
Date:10/11/2007

PHILADELPHIA Researchers at the University of Pennsylvania School of Medicine have found that professional welders who work in enclosed spaces with poor ventilation may be at risk for loss of sense of smell. The study appears in Neurology.

This is the first study to clearly demonstrate that welders who work in confined spaces without adequate respiratory protection are at risk for damaging their sense of smell, says Richard Doty, PhD, Director, Smell & Taste Center, Professor, Department of Otorhinolaryngology, and senior study author. Although underappreciated, loss of smell function significantly alters quality of life. This important sense not only determines the flavors of foods and beverages, but serves as an early warning system for the detection of fire, dangerous fumes, leaking gas, spoiled foods, and polluted environments.

Using the University of Pennsylvania Smell Identification Test (UPSIT) a self-administered standardized test incorporating 40 scratch-and-sniff odors with multiple choice options to identify the odor the researchers quantitatively evaluated the olfactory function of 43 professional welders who worked in confined spaces on the San Francisco/Oakland Bay Bridge, and compared their test scores with those of matched normal controls.

Dr. Doty and colleagues found that the mean UPSIT scores of the welders were, on average, seven points lower than those of their matched controls (29.62 and 36.90). Thirty eight (88%) performed more poorly than their controls, although only 3 (7%) had a total loss of their sense of smell. The percentages of those with mild, moderate, or severe loss of the sense of smell were 30.2, 18.6, and 16.3. The researchers report that interestingly, of the 42 subjects who provided information regarding their sense of smell before being tested, more than half were unaware of a problem.

Blood tests were administered to test for blood levels of chemicals found in welding fumes. The blood tests revealed that 40.5% of the welders had abnormally elevated levels of manganese (Mn). Although this suggests that the welders were exposed mainly to Mn, it is not entirely clear whether Mn is the basis of their olfactory problems. In fact, the welders with the highest Mn blood levels exhibited better olfactory function than those with the lowest Mn blood levels.

The welders also underwent a neuropsychological test battery. Dr. Doty notes, however, that, The results of this study suggest that exposure to the fumes of welding can alter the ability to smell, and that changes in this important sensory system are not correlated with alterations in cognitive function, which also can be induced by toxins in welding fumes.

The researchers conclude that the basis of the smell loss among the welders is not entirely clear. They suggest that although the research shows that the welders had smell dysfunction in relation to the matched controls, additional groups, such as ones consisting of non-welder industrial workers, might be of value in better defining the causality.


'/>"/>

Contact: Kate Olderman Tavella
kate.olderman@uphs.upenn.edu
215-349-8369
University of Pennsylvania School of Medicine
Source:Eurekalert

Related medicine news :

1. Rural Canadians travel far for specialists: study
2. A new study surpasses Gene Therapy Hurdle
3. Tomato Sauce reduces Cancer Risk- Study
4. A question on study of Adult Stem Cell
5. Study on obesity and heart failure
6. National Lung Study in the process
7. Marijuana gateway theory strengthened by study of twins
8. Old theory of adaptation confirmed by new study
9. Study casts doubt on keyboard ills
10. Gene study links endometriosis, infertility
11. Study reveals how stress can make you sick
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2016)... Pittsburgh, PA (PRWEB) , ... May 26, 2016 ... ... transplantation, and one that has a significant negative impact on long-term patient survival, ... to date. The results, published online this week in the Journal of Thoracic ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... solutions for drugs, biologics, consumer health and global clinical supply services, today announced ... to support the company’s continued investment and strategic growth plans in the Asia ...
(Date:5/26/2016)... ... May 26, 2016 , ... In an effort to provide hair restoration information to the ... users and those who do not use the app. Dr. Mohebi, the founder of Parsa ... Dr. Mohebi Live . , Dr. Mohebi says, “The positive response to the Snapchat ...
(Date:5/26/2016)... ... 26, 2016 , ... Eating Recovery Center, Washington ... a brand new child and adolescent residential treatment center on June 1. The ... more specialized eating disorder treatment and access to life-saving care. , To celebrate, ...
(Date:5/26/2016)... ... May 26, 2016 , ... Nike Yoga Camps at ... daily practices, arts & crafts, discussions, and games all geared towards enhancing your ... have combined backgrounds in kids’ yoga, collegiate sport yoga instruction, and global yoga ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... TARE (Transarterial Radio-embolization) Using ... and Overall Decreased Use of Hospital Resource ... specialist healthcare company, has today announced the publication ... of ISPOR (International Society for Pharmacoeconomics and Outcomes ... using yttrium-90 glass microspheres is associated with cost ...
(Date:5/26/2016)... , May 26, 2016 Since ... matured into an essential life science tool for conducting ... applications. BCC Research reveals in its new report that ... growth phase, one powered by a range of new ...      (Logo: http://photos.prnewswire.com/prnh/20140723/694805 ) , ...
(Date:5/25/2016)... May 25, 2016 According to ... Type (3D, 2D, 4D), by Therapeutic Area (Oncology, Cosmeceutical/Plastic ... User (Medical Device Manufacturers, Hospitals/ Clinics) - Forecast to ... Medical Animation Market for the forecast period of 2016 ... 301.3 Million by 2021 from USD 117.3 Million in ...
Breaking Medicine Technology: