Navigation Links
Penn study finds smoking prolongs fracture healing
Date:3/22/2013

Philadelphia Research has long shown the negative effects cigarette smoking has on cardiovascular health. But now, a new study from the Department of Orthopaedic Surgery at the Perelman School of Medicine at the University of Pennsylvania corroborates early evidence showing that cigarette smoking leads to longer healing times and an increased rate of post-operative complication and infection for patients sustaining fractures or traumatic injuries to their bone. The full results of the study are being presented this week at the 2013 American Academy of Orthopaedic Surgeons annual meeting in Chicago.

"Cigarette smoking is widely recognized as one of the major causes of preventable disease in the US, but there has been a lack of evidence showing other side effects of smoking, such as how it changes the way our bones heal," said Samir Mehta, MD, chief of the Orthopaedic Trauma and Fracture Service at Penn Medicine. "Our study adds substantial support to a growing body of evidence showing that smoking presents a significant risk to fracture patients. These risks need to be addressed with the patient both at the time of injury and when considering surgical treatment."

Results of the study show that for all injury types, fractured bones in patients who smoke take roughly six weeks longer to heal than fractured bones in a non-smoker (30.2 weeks compared to 24.1 weeks). Additional results show that fractured bones in patients who smoke are 2.3 times more likely to result in non-unions (non-healed fractures) than in non-smokers.

Using Medline, EMBASE and Cochrane computerized literature databases, the researchers collated previous studies that have examined the effects of smoking on bone and soft tissue healing. By analyzing these studies, the team sought to find an association between smoking and healing time, and various complications such as post-surgical infection. Studies included in the analysis focused on fractures of the tibia, femur or hip, ankle, humerus, and multiple long bones. In total, 6,480 patient cases (treated both surgically and non-surgically) were evaluated in the studies.

With approximately 6.8 million fractures requiring medical treatment in the US annually, the researchers say the overall burden of musculoskeletal disease is substantial. Though recent efforts have been made to promote bone health through vitamin and mineral supplements and nutritional support, the research team says that altering social factors such as encouraging smoking cessation have been under-addressed. This void is causing both a disconnect in the short-term treatment for patients and a missed opportunity to improve long-term health.

"The effects of smoking intervention programs need to be discussed and instituted to promote better outcomes for post-fracture patients," says Mehta. "We have an opportunity to help patients understand that it's about more than just heart health, and that smoking puts you at a higher risk of complications and leads to longer healing times."

The research team says future studies are needed to evaluate the dose-dependent effects of smoking on fracture healing. In addition, the increasing use and production of smokeless tobacco presents new questions about the effects of nicotine, and other tobacco products, through non-combustable forms. Finally, studies that better delineate the impact of directed education and the effects of the timing of smoking cessation (both before and after surgery) on the post-operative complication rate are also needed to provide the best care for fracture patients.


'/>"/>

Contact: Katie Delach
katie.delach@uphs.upenn.edu
215-776-6063
University of Pennsylvania School of Medicine
Source:Eurekalert

Related medicine news :

1. Ready-to-Eat Foods for Toddlers Often Too Salty: Study
2. Study highlights variations in spinal component costs
3. Mental Illness May Not Impede Healthy Weight Loss, Study Says
4. Study offers new way to discover HIV vaccine targets
5. Scripps Research study underlines potential of new technology to diagnose disease
6. Suicidal Thoughts More Common in Kids With Autism: Study
7. Most of Worlds Adults Consume Too Much Salt, Study Finds
8. Genetic risk strategies needed for young, black, female breast cancer patients, Moffitt study shows
9. Brain Changes Could Contribute to Gulf War Illness: Study
10. Study Reveals Weight Loss Supplement Prescopodene Increases Weight Loss By As Much As 9 Times
11. Moffitt Cancer Center researchers study use of dasatinib for patients with high-risk MDS
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2016)... ... April 28, 2016 , ... CastCoverz!, America’s #1 trusted brand ... country's oldest waterproof cast protector . As the largest one-stop, orthopedic shop, ... of daily, night, weatherproof and waterproof covers for most orthopedic devices, including but ...
(Date:4/28/2016)... ... April 28, 2016 , ... University of New England President Danielle N. Ripich ... president of Student Engagement. In addition to his role as director of Athletics, ... , “In the space of just one year Jack has distinguished himself by ...
(Date:4/28/2016)... ... 2016 , ... The ARRS 2016 Annual Meeting ... from around the globe who attended a week’s worth of cutting-edge scientific presentations, ... included the introduction of the 2016 ARRS Distinguished Educator, Dr. Gerald F. Abbott, ...
(Date:4/28/2016)... D.C., (PRWEB) , ... April 28, 2016 , ... ... systems, and the Campaign for Tobacco-Free Kids, a leading force in the fight ... promote federal, state and local policies that can help reduce tobacco use. The ...
(Date:4/28/2016)... ... , ... In many parts of the world, contamination from human waste is ... true in underdeveloped parts of Africa where clean sources of food and water are ... Morocco, will examine this global health issue and consider how it compares to other ...
Breaking Medicine News(10 mins):
(Date:4/27/2016)... Oasmia Pharmaceutical AB (NASDAQ: ... new generation of drugs within human and veterinary ... Paclical/Apealea in the Phase III study that included ... cancer. These preliminary results showed non-inferiority between the ... versus Taxol in combination with carboplatin. In fact, ...
(Date:4/26/2016)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO) is pleased to ... D., to Vice President of Education and Quality. ... continue to lead and oversee Diplomat University, an innovative ... training to Diplomat employees and external professionals on topics ... houses the quality assurance department, which focuses on programs ...
(Date:4/26/2016)... , April 26, 2016 ... Assessment and Credit Risk Analysis of the Biological Medicine ... This comprehensive report analyzes the financial assessment and ... China . The report provides readers with ... topics all market participants should be aware of. It ...
Breaking Medicine Technology: