Navigation Links
Penn researchers find link between sleep and immune function in fruit flies
Date:4/21/2014

PHILADELPHIA - When we get sick it feels natural to try to hasten our recovery by getting some extra shuteye. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that this response has a definite purpose, in fruitflies: enhancing immune system response and recovery to infection. Their findings appear online in two related papers in the journal Sleep, in advance of print editions in May and June.

"It's an intuitive response to want to sleep when you get sick," notes Center for Sleep and Circadian Neurobiology research associate Julie A. Williams, PhD. "Many studies have used sleep deprivation as a means to understand how sleep contributes to recovery, if it does at all, but there is surprisingly little experimental evidence that supports the notion that more sleep helps us to recover. We used a fruitfly model to answer these questions." Along with post-doctoral fellow, Tzu-Hsing Kuo, PhD, Williams conducted two related studies to directly examine the effects of sleep on recovery from and survival after an infection.

In the first paper, they took a conventional approach by subjecting fruit flies to sleep deprivation before infecting them with either Serratia marcescens or Pseudomonas aeruginosa bacteria. Both the sleep-deprived flies and a non-sleep-deprived control group displayed increased sleep after infection, what the experimenters call an "acute sleep response."

Unexpectedly, the pre-infection, sleep-deprived flies had a better survival rate. "To our surprise they actually survived longer after the infection than the ones who were not sleep-deprived," notes Williams. The Penn team found that prior sleep deprivation made the flies sleep for a longer period after infection as compared to the undisturbed controls. They slept longer and they lived longer during the infection. Inducing sleep deprivation after infection rather than before made little difference, as long as the infected
'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Penn Medicine researchers uncover hints of a novel mechanism behind general anesthetic action
2. CU researchers discover target for treating dengue fever
3. BUSM researchers find anti-seizure drug may reduce alcohol consumption
4. Researchers identify children with emotional behavior difficulties
5. Researchers identify similarities between HIV/AIDS and opioid addiction epidemics
6. Oxytocin, the love hormone, promotes group lying, according to Ben-Gurion U. researchers
7. Researchers develop device that simulates gastro-intestinal tract
8. UNC researchers show cancer chemotherapy accelerates molecular aging
9. NUS researchers developed worlds first fluorescent sensor to detect date rape drug
10. Cancer researchers find key protein link
11. Researchers: Biomarkers predict effectiveness of radiation treatments for cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Penn researchers find link between sleep and immune function in fruit flies
(Date:12/20/2014)... MissyDress, a distinguished special dress supplier, has just done ... drastically cut prices to all its prom dresses already, ... 2015. Many of the hottest styles are sold here ... and more. , A spokesman for MissyDress says, “The ... princess prom dresses or sweetheart chiffon prom dresses, you ...
(Date:12/20/2014)... (PRWEB) December 20, 2014 An improving ... sector have benefited the Massage Services industry ... characteristics of industry products, the anticipated 1.0% annualized increase ... has provided consumers with the means to afford additional ... received a massage in a given year has declined ...
(Date:12/20/2014)... (PRWEB) December 20, 2014 DePuy ... a metal-on-metal version of the artificial hip system ... state and federal courts, Bernstein Liebhard LLP reports. ... Bergen County Superior Court on December 2nd, counsel ... begin deposition of plaintiffs on November 19, 2014, ...
(Date:12/20/2014)... 20, 2014 (HealthDay News) -- The holidays can be ... contend with fresh trees, scented candles and other allergy ... the decorations that have been packed away in dank ... allergy and asthma patients," Dr. Rachna Shah, an affiliate ... Medicine, said in Loyola news release. Shah, who ...
(Date:12/20/2014)... The Doctor’s Office Urgent Care of Paramus, New Jersey ... decade. They’ve treated over 40,000 patients while carrying out ... alternative to the Paramus area. , For 2015, the ... staff of top-notch board certified physicians: Christine Milosis MD, Sandra ... new doctors will work tirelessly to carry out The ...
Breaking Medicine News(10 mins):Health News:MissyDress: The Prices of Prom Dresses Just Reduced 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 2Health News:Massage Services in the US Industry Market Research Report from IBISWorld Has Been Updated 3Health News:New Jersey Court Overseeing DePuy Pinnacle Hip Lawsuits Issues New Order, Bernstein Liebhard LLP Reports 2Health News:New Jersey Court Overseeing DePuy Pinnacle Hip Lawsuits Issues New Order, Bernstein Liebhard LLP Reports 3Health News:New Jersey Court Overseeing DePuy Pinnacle Hip Lawsuits Issues New Order, Bernstein Liebhard LLP Reports 4Health News:Holiday Trimmings Can Trigger Allergies 2Health News:The Doctor's Office Urgent Care Adds 3 New Physicians to Their Growing Medical Team 2
... physically abused in Germany. Many more, some 12,000 to 13,000, ... statistics, but in fact a high proportion of unreported cases ... Deutsches rzteblatt International contains an article in which Winfried ... present the findings of their representative survey of a sample ...
... Men and women infected with HIV reduced the risk of ... antiretroviral medicines when their immune systems were relatively healthy, according ... National Institute of Allergy and Infectious Diseases (NIAID), part of ... known as HPTN 052, was slated to end in 2015 ...
... Medical imaging facilities can now submit anonymized dose information ... (DIR) allowing them to compare their dose indices to ... national benchmarks. Participating facilities receive periodic feedback comparing their dose ... adjustments to lower dose received from scans. ...
... more than 35 years experience in breast imaging, has been ... of Radiology (ACR), the organization,s highest honor given for distinguished ... award will be presented to Bassett May 15 at the ... proud to be recognized by my peers for my contributions ...
... A Nordic multicentre study, headed by researchers from Karolinska ... using synthetic mesh can be more effective than traditional ... restored genital anatomy and more efficient symptom relief, although ... study is published in the renowned scientific periodical The ...
... that the vast majority of patients at high risk for ... statins as prescribed. That,s especially unfortunate, because the same study ... length of those patients, lives. "We found that only ... taking their prescribed dose on a regular basis after one ...
Cached Medicine News:Health News:Treating HIV-infected people with antiretrovirals significantly reduces transmission to partners 2Health News:Treating HIV-infected people with antiretrovirals significantly reduces transmission to partners 3Health News:Treating HIV-infected people with antiretrovirals significantly reduces transmission to partners 4Health News:ACR launches dose index registry 2Health News:UCLA cancer researcher wins prestigious Gold Medal from the American College of Radiology 2Health News:Synthetic mesh can improve outcome of prolapse surgery 2Health News:Study: Most at-risk patients don't adhere to statin treatment, despite real benefits 2
(Date:12/17/2014)... KENNESAW, Ga. and RALEIGH, ... Clinical Trial Marketing Communications, LLC (CTMC), and Integrated ... in patient recruitment and retention for clinical trials ... called Integrated Clinical Trial Marketing Services (i-CTMS). i-CTMS ... and retention services to pharmaceutical, biotechnology and medical ...
(Date:12/15/2014)... 2014 Registreer nu via  http://bit.ly/ag8Sypm14de ... 20. Februar sind alle akkreditierten pharmazeutischen Patientenversorgungsakten-Firmen ... PARTNER PROGRAMM ™ 2015 in ... Diese Tagung soll dazu beitragen, der Aegate ... neue profitablen Unternehmensdienstleistungen, die für Apotheken und ...
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... of the "Electrocardiogram (ECG) Devices - Global Trends, ... http://photos.prnewswire.com/prnh/20130307/600769 ... US$330 million by 2016. The North America ... global market share while Europe ...
Breaking Medicine Technology:Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3Symposium über Aegates Ecosystem-Partner-Programm für sichere Medikamente vom 19. - 20. Februar 2015 in Amsterdam 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 4
... YORK, Aug. 4, 2011 Reportlinker.com ... report is available in its catalogue: ... Technology, Devices, Markets, Players and Prospects ... http://www.reportlinker.com/p0581179/Microneedle-Drug-Delivery-Technology-Devices-Markets-Players-and-Prospects.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Drug_Delivery_Technology Microneedle technology ...
... UAE, August 4, 2011 Hospitals across India ... closing the gap between the quality of healthcare between city ... an umbrella term for new technology and techniques that facilitates ... industry as an answer to ensuring that India,s poorer classes ...
Cached Medicine Technology:Microneedle Drug Delivery: Technology, Devices, Markets, Players and Prospects 2Microneedle Drug Delivery: Technology, Devices, Markets, Players and Prospects 3Ministry of Science & Technology, Govt. of India to Drive e-Health Innovations - 2,69 Billion Rupees Sanctioned for Health Sector! 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: