Navigation Links
Penn receives $10 million to create center for orphan disease research and therapy
Date:7/26/2011

PHILADELPHIA - The Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania announces the launching of a first-of-its-kind interdisciplinary center focused on discovering novel treatments for orphan diseases. The Center will bring together, without institutional walls, all necessary approaches to attacking and treating orphan diseases: establishing dedicated research support facilities, translating findings into therapies, fostering targeted grant awards, and educating physicians and researchers.

Formation of the new Penn Center for Orphan Disease Research and Therapy was catalyzed by a $10 million gift from an anonymous donor, whose vision matched that of Penn Medicine in developing treatments for these diseases. The Center will fill a crucial need by providing the core laboratories, techniques, collaborative relationships, and expertise to lead an international, coordinated effort in the eradication of orphan diseases. Key among these resources is a state-of-the-art, robotically controlled drug screening laboratory that enables researchers from around the world to rapidly probe existing compound libraries for effective, orphan disease treatments.

Diseases are classified as orphan when they affect fewer than 200,000 people. However, as there are approximately 7,000 diseases now identified in this population, more than 25 million Americans are currently afflicted. Many of these diseases are caused by genetic mutations and are diagnosed in children. Research in many orphan diseases has lagged behind other major disease categories, such as diabetes and cardiovascular disease, in part because of a relative lack of technical expertise and funding mechanisms. Penn's Center will specifically address these needs.

"The research and development marketplace is not designed to optimally support research to develop the therapies so desperately needed for orphan diseases," explains Glen N. Gaulton, Ph.D., Executive Vice Dean and Chief Scientific Officer at the Perelman School. "Penn's new Center for Orphan Disease Research and Therapy will build not only strong collaborative relationships throughout Penn, but also with other leading academic medical centers, as well as public and private institutionsall designed to translate innovative research into the clinic. There's simply nothing else like it."

"This is a wonderful example of philanthropy in action," says J. Larry Jameson, M.D., Executive Vice President for the Health System and Dean of the Perelman School of Medicine. "The Center will be a natural extension of Penn's expertise in orphan diseases, and this strategic investment will galvanize support for orphan disease research around the globe. I am proud that Penn Medicine is taking a clear leadership position in transforming the health of millions."

Jameson adds that he is delighted that his predecessor, former Perelman School Dean Arthur H. Rubenstein, MBBCh, has agreed to serve as Acting Director for the Center, while an international search is conducted for a permanent director.

The Center will be a nexus for connecting:

  • Researchers and clinicians at Penn with other public and private institutions to work on projects aimed at finding and testing treatments for orphan diseases;
  • Approaches to treatment that are common among various orphan diseases;
  • Researchers with organizations that fund biomedical research for orphan diseases; and
  • Investigators within small and large pharmaceutical firms to develop and test treatments for orphan diseases.

Working together with other academic institutions, the National Institutes of Health, Pharma, and private philanthropy, the Center aims to reduce dramatically the technological and financial burden of investigators working in isolation by supporting a range of collaborative approaches:

  • Robotics for large-scale drug screening,
  • Biospecimen repositories to store samples,
  • Genotyping and bioinformatics services to identify causative genes,
  • Cell-based systems for developing new tests,
  • Nano-scale systems for developing new ways to deliver drugs, and
  • Small and large animal models for testing potential treatments.


'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert

Related medicine news :

1. NACDD Receives Two-Year Grant From Merck & Co., Inc. to Improve Diabetes Education
2. Dr Yaghouti of Global Laser Vision Receives Patient's Choice Award for 2009
3. UT researcher receives $2.4 million to research obesity, high-risk pregnancy
4. BestMassage.com Receives Award for Customer Trust
5. Corporate Wellness Firm Limeade Receives SAS 70 Type II Report
6. Oridion Receives Frost & Sullivan's 2010 Customer Value Enhancement Award
7. Special Olympics Georgia Receives Grant from The Home Depot Foundation
8. NOVAVAX, Inc. Receives NASDAQ Non-Compliance Letter
9. WuXi PharmaTech Receives AAALAC Accreditation for Suzhou Toxicology Facility
10. Verdan Receives Patent on Crystal Deodorant Spray
11. Thomas E. Mower Meets With Dalai Lama; Receives Prestigious Champion Award from Whole Child International
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... ... January 16, 2017 , ... Vixiar ... Officer of the medical device company, effective immediately. , “This is perfect timing ... has a strong track record in medical device market development and revenue growth, ...
(Date:1/15/2017)... ... January 15, 2017 , ... Going above and ... that strives to better communities around the world by offering the Gensuite team ... the opportunity for team members to become involved in a cause that is ...
(Date:1/15/2017)... ... ... "On Tour is a music themed slideshow production package which allows editors ... CEO of Pixel Film Studios. , On Tour’s new slide presets come with ... their slideshows. Place each slide on top of another slide or piece of media ...
(Date:1/15/2017)... ... January 15, 2017 , ... The Gravity Vault Indoor ... Radnor, Pennsylvania. As construction wraps up on the 14,000+ square foot climbing gym, the ... sixth location, including three in New Jersey and two in New York. With this ...
(Date:1/14/2017)... Glendale, CA (PRWEB) , ... January 13, 2017 ... ... published on Body and Soul, incorporating a magnesium-rich Mediterranean diet may lower the ... Leon Café and Lounge notes that the many health and wellness benefits linked ...
Breaking Medicine News(10 mins):
(Date:1/16/2017)... LONDON , Jan. 16, 2017  An aneurysm develops ... a balloon-like dilation. Aneurysms can occur in any ... essential blood vessel that supplies blood to legs. Most aortic ... through the abdomen and are referred as abdominal aortic aneurysms, ... the diameter of the aorta in the abdomen is about ...
(Date:1/16/2017)... Jan. 16, 2017  Verathon ® Inc., a leading manufacturer ... of new GlideScope ® Spectrum TM Single-Use video laryngoscopes. ... TM and Ambient Light Reduction TM technology, which actively ... ... Introducing another bright ...
(Date:1/16/2017)... 2017  According to Kalorama Information, the global ... at $4.9 billion for 2016.  The growing number ... aging population with significant diagnostic needs, along with ... the market for the modality.  The healthcare market ... focuses on the worldwide market, providing market size ...
Breaking Medicine Technology: