Navigation Links
Penn State professor investigates estrogen, heart disease connection in women
Date:5/4/2009

A new study on old rats by a Penn State researcher will shed light on the connection between estrogen deficiency, heart disease and aging in women.

Heart disease is the leading cause of death in women over the age of 75. After menopause, women lose their ability to produce the hormone estrogen and researchers believe that low estrogen levels somehow make women more vulnerable to heart disease and heart attack.

Donna Korzick, associate professor of physiology and kinesiology in Penn State's College of Health and Human Development, has a $1.8 million, five-year project funded by the National Heart, Lung and Blood Institute of the National Institutes of Health to figure out why estrogen deficiency puts women in danger for heart disease.

Korzick will identify proteins in heart cells that might be affected by both aging and low estrogen levels. She will work with Bruce Stanley, director of scientific programs, Penn State Milton S. Hershey Medical Center, to identify these proteins.

"Proteins are the work horses of the cells," said Korzick. "When they become activated, they can trigger different functions within the cell. Some are even responsible for cell death as we age."

Proteins can become 'activated' in a variety of ways, including by low estrogen levels.

Korzick will analyze the proteins within one segment of heart cells, the mitochondria. These are the "gate keepers of cell survival," says Korzick. The mitochondria play a significant role in whether or not a cell lives or dies as we age, especially while experiencing a heart attack.

"Cell death is a natural process," explained Korzick "But when heart cells die, it means that the remaining cells have to do more work. In this way, cell death is directly linked to how well the heart can withstand a stress like a heart attack."

After identifying the heart cell's proteins, Korzick will determine which proteins respond to low-estrogen environmen
'/>"/>

Contact: A'ndrea Elyse Messer
aem1@psu.edu
814-865-9481
Penn State
Source:Eurekalert

Page: 1 2

Related medicine news :

1. MyMedicalRecords, Inc. Stand-Alone Audited Financial Statements for the Period Ending December 31, 2008 to be Filed with the SEC Today, Monday, May 4, 2009
2. Vitamin E, Selenium and Soy Wont Prevent Prostate Cancer
3. Swine Flu Infections Now at 141 in 19 U.S. States
4. Althea Technologies Completes New State-of-the-Art, Commercial-Scale, Biologics and Injectables Manufacturing Facility
5. K-State professor awarded $1.48 million to study LASIK complictions
6. Oxygen Biotherapeutics, Inc. Files Cosmetic Product Ingredient Statement for new Oxycyte-based Cosmetic Gel
7. Texas Cancer Organizations Urge State Legislature to Fully Fund the Cancer Prevention and Research Institute of Texas
8. Official Statement From the Belize Tourism Board Regarding Swine Flu Pandemic
9. K-State Researcher Finds That the 1918 Spanish Flu Virus Can Infect Swine and Resulted in Current Lineage of H1N1 Swine Influenza Viruses
10. Penn State plays integral role in $35 million stress project
11. Wayne State University and Childrens Hospital of Michigan Research Team Discover Chemical That Plays a Major Role in Pediatric Obsessive-Compulsive Disorder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... Teen substance abuse has long been major issue ... adults never receive the professional treatment they need. To ... Troubled Teens Columbus helpline was established to provide a ... and alcohol dependencies . , By calling ... can speak directly to a representative who can offer ...
(Date:8/22/2014)... 22, 2014 Drug and alcohol ... the years, substance abuse has claimed thousands of lives ... OH is providing hope for teenagers who are seeking ... helpline is designed to provide adolescents and their parents ... find the best youth rehab facility to meet their ...
(Date:8/22/2014)... Dr Murray Grossan was interviewed for an ... In the October 2014 issue of Bottom Line Personal magazine, ... method of treating snoring, and in some cases Obstructive Sleep ... of all adults snore occasionally, and about 25% do it ... passages in the back of the throat tend to sag ...
(Date:8/22/2014)... August 22, 2014 According to ... System and Adaptive Cruise Control (ACC) System Market ... Forecasts 2014 - 2019", published by MarketsandMarkets, classifies ... Market in terms of volume and value. The ... years as well as covers review of the ...
(Date:8/21/2014)... Dallas, TX (PRWEB) August 22, 2014 ... proportion of reimbursement for medical expenses, the Chinese ... with its scale presenting a CAGR of 19.2% ... products are three product segments of orthopedic instruments ... bulk with 36.9% market share in 2013. , ...
Breaking Medicine News(10 mins):Health News:New Helpline in Columbus Assists Troubled Teen Find Youth Rehab 2Health News:Substance Abuse Helpline Provides Hope for Teens & Parents in Brunswick, OH 2Health News:Dr Murray Grossan Explains how and why Singing Exercises Stop Snoring 2Health News:Dr Murray Grossan Explains how and why Singing Exercises Stop Snoring 3Health News:Automotive Blind Spot Detection System Market Worth $2.8 Billion and Automotive Adaptive Cruise Control System Market Worth $6.1 Billion by 2019 – New Report 2Health News:Automotive Blind Spot Detection System Market Worth $2.8 Billion and Automotive Adaptive Cruise Control System Market Worth $6.1 Billion by 2019 – New Report 3Health News:Automotive Blind Spot Detection System Market Worth $2.8 Billion and Automotive Adaptive Cruise Control System Market Worth $6.1 Billion by 2019 – New Report 4Health News:China Orthopedic Instrument Industry Report, 2014-2017 Now Available at ChinaMarketResearchReports.com 2Health News:China Orthopedic Instrument Industry Report, 2014-2017 Now Available at ChinaMarketResearchReports.com 3Health News:China Orthopedic Instrument Industry Report, 2014-2017 Now Available at ChinaMarketResearchReports.com 4
... the star had a miscarriage in 2005 . ,Pregnancy ... they tied the knot in September 2005, and now Lesley Guynes ... in fact become pregnant, but she lost the baby. ... her own. Demi and Ashton have been trying (to have a ...
... rights group PETA has commended Sir Paul McCartney for his ... ,The former Beatle, who has supported cancer charities ... 1998, recently revealed that he is planning to decline financial ... that he took the decision after discovering that a number ...
... have confirmed a long-standing belief that male circumcision can ... an international AIDS conference will be told next week ... International AIDS Society (IAS) conference to be held in ... represented a major development in HIV prevention. ...
... alarming depletion of ground water levels in the country and ... water table. ,The Central Groundwater Board has ... level at various places across the country and identified about ... score, a senior official said. ,"The constant mining ...
... left-handers, natural lefties who have switched over to right hand ... their brains are organized, and how hard particular regions ... in such peoples brains continue to retain characteristics of a ... righty. ,"The question now is, 'do converts suffer ...
... Novartis AG has been given the green light from the European ... still no access to its American counterpart. ... European Medicines Agency came soon after Novartis said it would ... due to a request for more safety data. ...
Cached Medicine News:Health News:Male Circumcision can Cut HIV Infection, Studies Show 2Health News:Groundwater Levels Depleting Alarmingly in India 2Health News:Converting Left-hander to Right-hander also Changes the Brain 2
(Date:8/21/2014)... -- CVS Caremark Corporation (NYSE: CVS ) announced ... payable in connection with its previously announced cash tender offers ... any and all of its 6.250% Senior Notes due 2027 ... maximum amount of its 6.125% Senior Notes due 2039, 5.750% ... (collectively, the "Maximum Tender Offer Notes" and together with the ...
(Date:8/21/2014)... , Aug. 21, 2014 /CNW/ - Bedrocan Cannabis ... three independent members to its Board of Directors, ... experience of the company, a leading licensed producer ... . Internationally, Bedrocan has 13 years, experience in ... in seven countries, including Canada. ...
(Date:8/21/2014)... 2014  SI-BONE, Inc. ( San Jose, California ... use of the iFuse Implant System, ® a ... the sacroiliac (SI) joint, announced that Priority Health ( ... Lumbar Fusion Medical Policy No. 91590-R4 providing positive coverage ... states that the fusion procedure, which employs the iFuse ...
Breaking Medicine Technology:CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 2CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 3CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 4CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 5CVS Caremark Corporation Announces Early Results of Tender Offers, Pricing, Election of Early Settlement and Increase in the Maximum Tender Offer Amount 6Senior Life Sciences Executives Join Bedrocan as Independent Directors 2Senior Life Sciences Executives Join Bedrocan as Independent Directors 3SI-BONE, Inc. Announces Positive Coverage Decision by Priority Health 2SI-BONE, Inc. Announces Positive Coverage Decision by Priority Health 3
... 29, 2011  Solos Endoscopy, Inc. (OTCPK: SNDY) is pleased ... in 2012 through the development and sales of its ... management of medical conditions. In 2011, Solos Endoscopy consummated ... in debt for the Company. The signed settlement agreement ...
... Today, Zacks Equity Research discusses the Pharma & Biotech, ... Human Genome Sciences Inc. (Nasdaq: HGSI ... and Perrigo Company (Nasdaq: PRGO ). ... synopsis of today,s Industry Outlook is presented below. The ...
Cached Medicine Technology:Solos Endoscopy, Inc. is Primed for Growth in 2012 2Solos Endoscopy, Inc. is Primed for Growth in 2012 3Zacks Industry Outlook Highlights: Vertex Pharma, Human Genome Sciences, Biogen Idec and Perrigo 2Zacks Industry Outlook Highlights: Vertex Pharma, Human Genome Sciences, Biogen Idec and Perrigo 3Zacks Industry Outlook Highlights: Vertex Pharma, Human Genome Sciences, Biogen Idec and Perrigo 4
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: