Navigation Links
Penn School of Medicine receives $2.3 million to study biomarkers of cigarette smoke exposure
Date:9/14/2007

say, Heres your DNA on smoking and heres DNA without smoking. This is my vision. Blair is also the Director of Penns Center for Cancer Pharmacology.

The researchers propose to screen smokers, non-smokers and those regularly in contact with second-hand smoke for a variety of biochemical markers. Previous studies have shown that chemical changes arise within the body, from the tissue level down to the DNA level in people who smoke or who have been exposed to smoke, but this association has never been studied on a large scale with reliable biomarkers.

The plan is to develop a panel of biochemicals, or biomarkers, that indicate if a person has been exposed to smoke to then distinguish between a group of non-smokers and disease-free tobacco smokers. They will test for the presence of these chemicals in smokers blood, urine, and breath. These studies will provide important base-line data for subsequent studies that will relate cigarette smoke exposure to incidence and genetic susceptibility to tobacco-related disease of the lung and cardiovascular system.

The Penn program has already implemented patient recruitment through the participation of Anil Vachani, MD, Assistant Professor of Medicine. It is anticipated that substantial new information will become available on the presence of various biomarkers so that Andrea Troxel, PhD, Associate Professor of Biostatistics, can assess their potential utility. In addition to determining conventional lipid and DNA biomarkers, a discovery program will be implemented in collaboration with Don Baldwin, PhD, Director of the Penn Microarray Core Facility, in order to identify potential protein biomarkers.

The Principal Investigators from each of the funded projects in the GEI will meet at the National Institutes of Health in December 2007 so that the projects can benefit from the individual expertise of the various participants. Annual meetings between the investigators will then take place over
'/>"/>

Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. School Children Put To Risk Due To Shortage Of Nurses
2. Schools and Bars closed in Rwanda due to Cholera outbreak
3. Does Success in School Differ From the Real World Success ?
4. Preschoolers eat more when served in bigger helpings
5. Watching TV in the bedroom can lower children’s school performanc
6. Exposure to Pesticides in Schools Produces Illnesses Among Employees, Students
7. Adolescents Who Walk To School Are Fitter, More Active
8. Safe Neighborhood Means Less TV For Preschool Children
9. Popularity Among Peers Increases Susceptibility To Smoking Habit Among School Children
10. Vitamin filled nutrition candy for School children
11. Fish Oil supplementation reduces physical aggression in school children’
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2014)... of cell in the lining of the bladder is ... to researchers at the Stanford University School of Medicine. ... to pinpoint the normal cell type that can give ... to show that most bladder cancers and their associated ... why many human bladder cancers recur after therapy. , ...
(Date:4/18/2014)... medical-testing device is being prepped to enter the ... diagnosis of certain diseases in remote areas, thanks ... of investigations aboard the International Space Station on ... space-tested concept of capillary flow to diagnose infectious ... Kelso, Ph.D., a researcher at Northwestern University in ...
(Date:4/18/2014)... neuroscientists have made a discovery that turns 160 years ... insulating material long known to be essential for the ... cells, is not as ubiquitous as thought, according to ... the Harvard Stem Cell Institute (HSCI) and the University,s ... with Professor Jeff Lichtman, of Harvard,s Department of Molecular ...
(Date:4/18/2014)... did it make you feel? According to psychologists, remembering ... as how sad you were or how embarrassed you ... can,t stop thinking about it. , When these ... the memories, rather than how you felt, is a ... effects of these memories, a new study suggests. , ...
(Date:4/18/2014)... psychologists have made a brain-related discovery that could ... , This discovery opens up the possibility that ... a specific brain activity that the researchers have ... Journal of Neuroscience has just published ... an associate professor of psychology and his doctoral ...
Breaking Medicine News(10 mins):Health News:Stanford scientists identify source of most cases of invasive bladder cancer 2Health News:Stanford scientists identify source of most cases of invasive bladder cancer 3Health News:Stanford scientists identify source of most cases of invasive bladder cancer 4Health News:Stanford scientists identify source of most cases of invasive bladder cancer 5Health News:Space-tested fluid flow concept advances infectious disease diagnoses 2Health News:Space-tested fluid flow concept advances infectious disease diagnoses 3Health News:Finding turns neuroanatomy on its head 2Health News:Finding turns neuroanatomy on its head 3Health News:New study suggests a better way to deal with bad memories 2Health News:New study suggests a better way to deal with bad memories 3Health News:Scientists discover brain's anti-distraction system 2
... study raises the question, do barriers to health ... risk of tuberculosis? The study, published in the ... Diseases and now available online, suggests that ... seeking care than documented immigrants or U.S.-born patients, ...
... CHICAGO October 29, 2008 Shire plc (LSE: ... announced results from a 13-hour analog classroom study in ... Deficit Hyperactivity Disorder (ADHD). In this study, researchers ... time point measured (1.5 hours) through the last time ...
... 29 Trust for America,s,Health (TFAH) released ... Why Emerging,Infectious Diseases Are a Threat to ... die annually from newly emerging and re-emerging,infectious ... during a,severe flu pandemic or yet-unknown disease ...
... ARE PASSIVE AND INEFFECTIVE, NEW YORK, Oct. ... should be using the most effective tool,to protect ... Betsy,McCaughey, Ph.D., Chairman of the not-for-profit Committee to ... physicians., Today, RID is releasing a new ...
... drug resistance and climate change as culprits , , WEDNESDAY, ... die each year from infectious diseases, and that number ... That dire news was delivered in a report, ... Threat to America , released Wednesday by the Trust ...
... Foundation,Radiology Group (FRG) signed a multi-year contract with ... of diagnostic,imaging services effective December 31, 2008., ... Pennsylvania,and services multiple counties in north central Pennsylvania ... wide range of primary and,secondary health care services ...
Cached Medicine News:Health News:Health-care barriers for undocumented immigrants: Raising tuberculosis risk? 2Health News:VYVANSE provided behavior, inattention and math test score improvements in children with ADHD 2Health News:VYVANSE provided behavior, inattention and math test score improvements in children with ADHD 3Health News:New Report Finds Rising Risk of Infectious Diseases in America 2Health News:New Report Finds Rising Risk of Infectious Diseases in America 3Health News:New Report Finds Rising Risk of Infectious Diseases in America 4Health News:New Report Finds Rising Risk of Infectious Diseases in America 5Health News:New Report Finds Rising Risk of Infectious Diseases in America 6Health News:Professional Sports Teams Should Use MRSA Screening and Other Aggressive Methods to Prevent Staph Infections 2Health News:Threat From Infectious Diseases Growing 2Health News:Threat From Infectious Diseases Growing 3Health News:Foundation Radiology Group Announces Multi-Year Deal with Charles Cole Memorial Hospital 2
(Date:1/15/2014)... (the "Company") (NASDAQ: CLSN ) today announced ... purchase an aggregate of approximately $15 million of the ... led by a dedicated health care fund. ... investors pursuant to which the Company agreed to sell ...
(Date:1/15/2014)... Jan. 15, 2014  Manufacturers, suppliers and distributors of ... to protect their most important business assets, intellectual ... ) Because of the highly-competitive nature ... one of the most litigious industry sectors of ...
(Date:1/15/2014)... , Jan. 15, 2014 The Cadence Fitness ... Fitness Center by the Medical Fitness Association, a non-profit ... achieve their full potential. The Cadence Fitness & Health ... western suburbs and second in the Chicagoland area. ...
Breaking Medicine Technology:Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3Intellectual Property Insurance for Medical-related Products and Services 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3
... a Little Help ... Series,PSA Expands Partnership Between VH1 and Nothing But Nets to Prevent Malaria ... in Africa, ... very serious issue in a new Public,Service Announcement (PSA) created by VH1 for Nothing But ...
... Immtech Pharmaceuticals,Inc. (Amex: IMM ) today announced ... consortium led by the University of North Carolina ... Bill & Melinda Gates Foundation,(the "Gates Foundation"), to ... leishmania. This grant is part of the $22.6,million ...
Cached Medicine Technology:'Best Week Ever' for Nothing But Nets 2'Best Week Ever' for Nothing But Nets 3Immtech Receives $5.1 Million to Further African Sleeping Sickness Clinical Trials 2Immtech Receives $5.1 Million to Further African Sleeping Sickness Clinical Trials 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: