Navigation Links
Pediatric obesity may alter thyroid function and structure
Date:12/3/2008

Chevy Chase, MDIn addition to its strong associations with hypertension, cardiovascular disease, and diabetes, pediatric obesity may induce alterations in thyroid function and structure, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

Thyroid hormones drive metabolism, however demonstration of a direct or strong correlation of obesity with deficient thyroid function has been controversial, and previous studies provide conflicting conclusions. While some studies have found that thyroid disorders may lead to obesity, this recent study shows that in some cases, it is the obesity that may cause the disorder.

"Our study shows that alterations in thyroid function and structure are common in obese children and we may have uncovered the link," said Giorgio Radetti, M.D., of the Regional Hospital of Bolzano in Italy and lead author of the study. "We found an association between body mass index and thyroid hormone levels which suggests that fat excess may have a role in thyroid tissue modification."

This study evaluated 186 overweight and obese children over a period of nearly three years. Researchers measured subjects' thyroid hormone levels and thyroid antibodies and also performed a thyroid ultrasound.

The presence of thyroid antibodies would suggest a diagnosis of Hashimoto's thyroiditis, an autoimmune disease of the thyroid where T-cells attack the cells of the thyroid. In this study, 73 children did not show these antibodies, yet their ultrasound pattern was still suggestive of Hashimoto's thyroiditis.

"The ultrasound findings are a bit mysterious," said Dr. Radetti. "However, the findings do suggest the existence of a low-grade inflammation state, which has been known to characterize obesity."

Thyroid function has been shown to return to normal after weight loss, said Dr Radetti, raising the question of the potential reversibility of thyroid abnormalities shown on an ultrasound. However, researchers still do not know whether the persistence of thyroid abnormalities in obese children may also progress into chronic thyroid disease in early adulthood. Dr. Radetti says more studies are needed to answer these questions.


'/>"/>

Contact: Aaron Lohr
alohr@endo-society.org
240-482-1380
The Endocrine Society
Source:Eurekalert

Related medicine news :

1. WVU Announces Creation of Multimillion Dollar Pediatric Research Institute
2. Pediatric Heart Surgeons May Be Best Choice for Adults
3. Super Jake Foundation Hosts 4th Annual Heroes Bash on Nov. 8 to Benefit Pediatric Cancer Research
4. Pediatricians Could Help Screen for Alcohol Abuse in Home
5. Parents comfortable with alcohol screening in pediatricians offices
6. NO on Prop 8 Campaign Releases Statement by 300 California Pediatricians
7. Children's National Experts Presenting at American Academy of Pediatrics Conference
8. American Academy of Pediatrics Elects a New Leader
9. Pediatrics Bioethics Conference to Be Held in Jacksonville, Florida, October 10-11, 2008
10. Pediatrichealthchannel.com - New Site for Parents Seeking Answers to Children's Health Questions
11. PediatricRespiratory.org Announces a Two-Part, Live CME/CE Webcast Series on RSV and Pediatric Influenza
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/29/2016)... ... 29, 2016 , ... World Patent Marketing , a ... invention which aids in proper muscle development. , "The Gym & Exercise Equipment ... of World Patent Marketing. "Globalization has threatened the future growth of the industry ...
(Date:4/29/2016)... ... April 29, 2016 , ... The Gluten-Free Certification Program (GFCP), ... announce the launch of the GFCP Scoop in response to consumer ... of the GFCP Scoop site is to keep the gluten-free community ...
(Date:4/29/2016)... CA (PRWEB) , ... April 29, 2016 , ... Melanoma is the deadliest type of ... to blame for the majority of skin cancer deaths. More than 10,000 people are expected ... age at diagnosis is 62, it is the one of the most commonly diagnosed cancers ...
(Date:4/29/2016)... ... ... Dr. Robert Mondavi, one of the dentists in Torrance , is ... field as more patients are discovering the many different ways they can change and ... available to them and which ones might work for their smiles. , “One ...
(Date:4/29/2016)... ... , ... New York City based oral and maxillofacial surgeon Dr. Majid Jamali is ... treat obstructive sleep apnea. Dr. Jamali is proud to offer this permanent solution to patients ... or both jaw bones. This surgery is performed to correct the alignment of the jaw. ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... 29, 2016 Acquisition Expands ... Product Development Capabilities in North America ... . Indegene ( http://www.indegene.com ), ... acquisition of Skura Corporation,s life science business. Skura,s ... sales enablement technology for life science organizations and ...
(Date:4/29/2016)... 29, 2016 ... Sanofi, leader mondial et ... résultats pour le premier trimestre 2016. ... Contamine, commente les résultats du premier ... pour le reste de l,année. ...
(Date:4/29/2016)... Glycotope GmbH, a clinical-stage immuno-oncology company built ... Dr. Alfredo Zurlo as Chief Medical Officer. ... years clinical experience and a proven track record in ... at Mologen AG where he was Chief Medical Officer ... held various positions at F Hoffmann La Roche and ...
Breaking Medicine Technology: