Navigation Links
Pediatric Ear Infection Vaccine Shows Promise
Date:5/21/2009

Animal study shows droplets rubbed into skin prevented infections

THURSDAY, May 21 (HealthDay News) -- Vaccines delivered via droplets rubbed into the skin appear to protect against ear infections, say researchers who tested the method on chinchillas.

If this approach proves effective in humans, it could provide a simple, inexpensive way of preventing ear infections, the researchers noted.

Three groups of chinchillas had droplets of the vaccines rubbed into the skin of their ears once a week for three weeks. A fourth group received a placebo. After receiving the vaccines or placebo, the animals were infected with nontypeable haemophilus influenzae (NTHi), one of the three main bacterial causes of otitis media, an infection/inflammation of the middle ear.

The chinchillas that received the vaccines were able to very rapidly reduce, or eliminate NTHi from their nose and ears, but this wasn't the case in the animals that received the placebo. The findings were presented May 21 at the American Society for Microbiology annual meeting, in Philadelphia.

"Our data are the first to show that transcutaneous immunization is an effective way to prevent experimental ear infections and lays the foundation for an effective, yet simple, inexpensive -- and potentially transformative -- way to deliver vaccines," Laura Novotny, of the Research Institute at Nationwide Children's Hospital in Columbus, Ohio, said in a news release.

"We have designed several vaccine candidates which target proteins on the outer surface of this bacterium [NTHi]. Previous work in our lab showed that after immunization by injection, each of the three vaccine candidates prevented experimental ear infections caused by NTHi. In this study, we now wanted to test an alternative but potentially equally effective method to deliver a vaccine," Novotny said.

It is estimated that up to 83 percent of children in the United States will have at least one ear infection by the time they're 3, according to the news release.

More information

The U.S. National Institute on Deafness and Other Communication Disorders has more about ear infections.



-- Robert Preidt



SOURCE: American Society for Microbiology, news release, May 21, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. APA Comments on FDAs First Approval of Medication to Treat Pediatric Schizophrenia and Bipolar Disorder
2. Parental surveys boost diagnosis abilities of pediatricians
3. Nautica Malibu Triathlon Presented by Toyota Raises $718,000 for Childrens Hospital Los Angeles Pediatric Cancer Research
4. Super Jake Foundation Offers Hope for Pediatric Cancer
5. FDA Panel Recommends Approval of SyntheMeds REPEL-CV(R) Adhesion Barrier for Pediatric Patients
6. Verus Pharmaceuticals Announces Divestiture of Pediatric Asthma Development Programs to AstraZeneca
7. Super Jake Foundation Hosts 3rd Annual Heroes Bash on Nov. 3 to Benefit Pediatric Cancer Research
8. Statement from the Consumer Healthcare Products Association on the Safety of Pediatric Over-the-Counter Medicines
9. UT Southwestern investigating hypothermic technique in treating pediatric head injuries
10. Washington Capitals to Visit Patients at Childrens National Medical Center, Announce Launch of Initiative to Fight Pediatric Cancer
11. Pediatricians Awarded for Innovative Approaches to Combat Childhood Obesity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Pediatric Ear Infection Vaccine Shows Promise
(Date:6/25/2016)... ... , ... First Choice Emergency Room , the largest network of independent ... Director of its new Mesquite-Samuell Farm facility. , “We are pleased to announce ... Dr. James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van ... Wellness at Work award to iHire in recognition of their exemplary accomplishments in worksite ... 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum ...
(Date:6/24/2016)... ... 2016 , ... Those who have experienced traumatic events may suffer from a ... such as drug or alcohol abuse, as a coping mechanism. To avoid this pain ... following a traumatic event. , Trauma sufferers tend to feel a range of emotions, ...
(Date:6/24/2016)... Dallas, Texas (PRWEB) , ... June 24, 2016 ... ... 12th International Conference and Scientific Sessions in Dallas that it will receive two ... Announcement of the grants came as PHA marked its 25th anniversary by recognizing ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 Research and Markets ... for Companion Diagnostic Tests" report to their offering. ... Companion Diagnostics The World Market for Companion ... medicine diagnostics. Market analysis in the report includes the following: ... (In Vitro Diagnostic Kits) by Region (N. America, EU, ROW), ...
(Date:6/24/2016)... KNOXVILLE, Tenn. , June 24, 2016 /PRNewswire/ ... market providing less invasive and more durable cerebrospinal ... million in funding.  The Series-A funding is led ... the Lighthouse Fund, and other private investors.  Arkis, ... less-invasive neurosurgical instrumentation and the market release of ...
(Date:6/23/2016)... Research and Markets has announced the addition ... Chemical (Sugar, Petrochemical, Glycerin), Inorganic Chemical), Functionality (Filler, Binder, ... Forecast to 2021" report to their offering. ... excipients market is projected to reach USD 8.1 Billion ... forecast period 2016 to 2021. The ...
Breaking Medicine Technology: