Navigation Links
Pediatric Ear Infection Vaccine Shows Promise
Date:5/21/2009

Animal study shows droplets rubbed into skin prevented infections

THURSDAY, May 21 (HealthDay News) -- Vaccines delivered via droplets rubbed into the skin appear to protect against ear infections, say researchers who tested the method on chinchillas.

If this approach proves effective in humans, it could provide a simple, inexpensive way of preventing ear infections, the researchers noted.

Three groups of chinchillas had droplets of the vaccines rubbed into the skin of their ears once a week for three weeks. A fourth group received a placebo. After receiving the vaccines or placebo, the animals were infected with nontypeable haemophilus influenzae (NTHi), one of the three main bacterial causes of otitis media, an infection/inflammation of the middle ear.

The chinchillas that received the vaccines were able to very rapidly reduce, or eliminate NTHi from their nose and ears, but this wasn't the case in the animals that received the placebo. The findings were presented May 21 at the American Society for Microbiology annual meeting, in Philadelphia.

"Our data are the first to show that transcutaneous immunization is an effective way to prevent experimental ear infections and lays the foundation for an effective, yet simple, inexpensive -- and potentially transformative -- way to deliver vaccines," Laura Novotny, of the Research Institute at Nationwide Children's Hospital in Columbus, Ohio, said in a news release.

"We have designed several vaccine candidates which target proteins on the outer surface of this bacterium [NTHi]. Previous work in our lab showed that after immunization by injection, each of the three vaccine candidates prevented experimental ear infections caused by NTHi. In this study, we now wanted to test an alternative but potentially equally effective method to deliver a vaccine," Novotny said.

It is estimated that up to 83 percent of children in the United States will have at least one ear infection by the time they're 3, according to the news release.

More information

The U.S. National Institute on Deafness and Other Communication Disorders has more about ear infections.



-- Robert Preidt



SOURCE: American Society for Microbiology, news release, May 21, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. APA Comments on FDAs First Approval of Medication to Treat Pediatric Schizophrenia and Bipolar Disorder
2. Parental surveys boost diagnosis abilities of pediatricians
3. Nautica Malibu Triathlon Presented by Toyota Raises $718,000 for Childrens Hospital Los Angeles Pediatric Cancer Research
4. Super Jake Foundation Offers Hope for Pediatric Cancer
5. FDA Panel Recommends Approval of SyntheMeds REPEL-CV(R) Adhesion Barrier for Pediatric Patients
6. Verus Pharmaceuticals Announces Divestiture of Pediatric Asthma Development Programs to AstraZeneca
7. Super Jake Foundation Hosts 3rd Annual Heroes Bash on Nov. 3 to Benefit Pediatric Cancer Research
8. Statement from the Consumer Healthcare Products Association on the Safety of Pediatric Over-the-Counter Medicines
9. UT Southwestern investigating hypothermic technique in treating pediatric head injuries
10. Washington Capitals to Visit Patients at Childrens National Medical Center, Announce Launch of Initiative to Fight Pediatric Cancer
11. Pediatricians Awarded for Innovative Approaches to Combat Childhood Obesity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Pediatric Ear Infection Vaccine Shows Promise
(Date:6/24/2016)... ... June 24, 2016 , ... A recent article published ... unfamiliar with. The article goes on to state that individuals are now more comfortable ... less common operations such as calf and cheek reduction. The Los Angeles area medical ...
(Date:6/24/2016)... ... ... crisis. Her son James, eight, was out of control. Prone to extreme mood shifts and ... him, he couldn’t control his emotions,” remembers Marcy. “If there was a knife on ... say he was going to kill them. If we were driving on the freeway, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, ... treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including robotic ... osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It ...
(Date:6/24/2016)... ... ... People across the U.S. are sharpening their pencils and honing their writing skills ... patients and their families pay tribute to a genetic counselor by nominating him or ... Counselors (NSGC) Annual Education Conference (AEC) this September. , In April, Genome magazine ...
(Date:6/24/2016)... ... June 24, 2016 , ... Puradigm® & ... (TGIG), has initiated cultivation and processing operations at its production facility, and opened ... , Puradigm is the manufacturer of a complete system of proactive air and ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... DUBLIN , June 23, 2016 ... "Dialysis Devices Global Market - Forecast to 2022" report ... is the treatment method for the patients with kidney failure, ... and excess fluid from the patient,s blood and thus the ... sodium, potassium and chloride in balance. Increasing ...
(Date:6/23/2016)... , June 23, 2016 ... "Pharmaceutical Excipients Market by Type (Organic Chemical (Sugar, ... Formulation (Oral, Topical, Coating, Parenteral) - Global Forecast to ... The global pharmaceutical excipients market ... at a CAGR of 6.1% in the forecast period ...
(Date:6/23/2016)... 23, 2016 Roche (SIX: RO, ROG; OTCQX: ... its Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated ... shock. With this clearance, Roche is the first IVD ... solution for sepsis risk assessment and management. ... and PCT levels in blood can aid clinicians in ...
Breaking Medicine Technology: