Navigation Links
Pediatric Ear Infection Vaccine Shows Promise
Date:5/21/2009

Animal study shows droplets rubbed into skin prevented infections

THURSDAY, May 21 (HealthDay News) -- Vaccines delivered via droplets rubbed into the skin appear to protect against ear infections, say researchers who tested the method on chinchillas.

If this approach proves effective in humans, it could provide a simple, inexpensive way of preventing ear infections, the researchers noted.

Three groups of chinchillas had droplets of the vaccines rubbed into the skin of their ears once a week for three weeks. A fourth group received a placebo. After receiving the vaccines or placebo, the animals were infected with nontypeable haemophilus influenzae (NTHi), one of the three main bacterial causes of otitis media, an infection/inflammation of the middle ear.

The chinchillas that received the vaccines were able to very rapidly reduce, or eliminate NTHi from their nose and ears, but this wasn't the case in the animals that received the placebo. The findings were presented May 21 at the American Society for Microbiology annual meeting, in Philadelphia.

"Our data are the first to show that transcutaneous immunization is an effective way to prevent experimental ear infections and lays the foundation for an effective, yet simple, inexpensive -- and potentially transformative -- way to deliver vaccines," Laura Novotny, of the Research Institute at Nationwide Children's Hospital in Columbus, Ohio, said in a news release.

"We have designed several vaccine candidates which target proteins on the outer surface of this bacterium [NTHi]. Previous work in our lab showed that after immunization by injection, each of the three vaccine candidates prevented experimental ear infections caused by NTHi. In this study, we now wanted to test an alternative but potentially equally effective method to deliver a vaccine," Novotny said.

It is estimated that up to 83 percent of children in the United States will have at least one ear infection by the time they're 3, according to the news release.

More information

The U.S. National Institute on Deafness and Other Communication Disorders has more about ear infections.



-- Robert Preidt



SOURCE: American Society for Microbiology, news release, May 21, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. APA Comments on FDAs First Approval of Medication to Treat Pediatric Schizophrenia and Bipolar Disorder
2. Parental surveys boost diagnosis abilities of pediatricians
3. Nautica Malibu Triathlon Presented by Toyota Raises $718,000 for Childrens Hospital Los Angeles Pediatric Cancer Research
4. Super Jake Foundation Offers Hope for Pediatric Cancer
5. FDA Panel Recommends Approval of SyntheMeds REPEL-CV(R) Adhesion Barrier for Pediatric Patients
6. Verus Pharmaceuticals Announces Divestiture of Pediatric Asthma Development Programs to AstraZeneca
7. Super Jake Foundation Hosts 3rd Annual Heroes Bash on Nov. 3 to Benefit Pediatric Cancer Research
8. Statement from the Consumer Healthcare Products Association on the Safety of Pediatric Over-the-Counter Medicines
9. UT Southwestern investigating hypothermic technique in treating pediatric head injuries
10. Washington Capitals to Visit Patients at Childrens National Medical Center, Announce Launch of Initiative to Fight Pediatric Cancer
11. Pediatricians Awarded for Innovative Approaches to Combat Childhood Obesity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Pediatric Ear Infection Vaccine Shows Promise
(Date:10/13/2017)... N.Y (PRWEB) , ... October 13, 2017 , ... Lori ... became a member of ElderCounsel, a national organization of elder law and special needs ... changing laws and rules. It also provides a forum to network with elder law ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional women, ... towards gender equality at their inaugural Summit in New York City in June. The ... social audience of over 3 million. To watch the Mobilize Women video, click ...
(Date:10/13/2017)... ... 13, 2017 , ... Coveros, a leader in agile coaching ... contract by the Center for Medicare and Medicaid Services (CMS). The Enterprise Agile ... of Agile methodologies in a consistent and high value manner across CMS programs. ...
(Date:10/12/2017)... Francisco, CA (PRWEB) , ... October 12, 2017 ... ... Dr. Cheng, are now treating sleep apnea using cutting-edge Oventus O2Vent ... apnea, a serious sleep disorder characterized by frequent cessation in breathing. Oral appliances ...
(Date:10/12/2017)... ... 2017 , ... The American College of Medical Informatics (ACMI) will present the ... Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium ... a pioneer in the field of medical informatics, this prestigious award is presented to ...
Breaking Medicine News(10 mins):
(Date:10/2/2017)... Oct. 2, 2017 Diplomat Pharmacy, Inc. (NYSE: ... Software and Consulting, LLC , and named its founder ... based in Tennessee , will operate ... expands EnvoyHealth,s service offerings for health care partners to ... "In an interoperable world, technology ...
(Date:10/2/2017)... COPENHAGEN, Denmark , Oct. 2, 2017 The ... tool in the struggle to reverse the tide of prescription ... plan for regulating their medicine intake and stepping down their ... is set to launch in December 2017; the first 100,000 ... access. Learn more at http://www.rebound-solution.com/ ...
(Date:9/27/2017)... and NEW YORK , Sept. 27, 2017 /PRNewswire/ ... health and big data solutions, today announced that its MyDario product is ... your local TV listings for when The Dr. Oz Show airs in ... The nine-time ... month. ...
Breaking Medicine Technology: