Navigation Links
Patients with lower urinary tract symptoms more likely to suffer from metabolic syndrome
Date:6/19/2009

New York, NY, June 18, 2009 Researchers have determined that individuals with mild to severe symptoms of lower urinary tract symptoms (LUTS) are more likely to suffer from metabolic syndrome (MetS), a collection of cardiovascular risk factors thought to be linked by insulin resistance). LUTS encompass voiding (incomplete emptying, weak stream, intermittency, straining) and storage (frequency, urgency, nocturia) difficulties.

In a study published in the August 2009 issue of The Journal of Urology, researchers from the New England Research Institutes, Watertown, Massachusetts; the Department of Urology, Northwestern University, Chicago, Illinois; Cornell University, Weill Medical College; Pfizer Inc, New York, New York; and Pfizer Ltd, Sandwich, United Kingdom, explored the possible association of LUTS with MetS using data from the Boston Area Community Health Survey. 2,301 men 30 to 79 years old were interviewed and analyses were conducted on 1,899 men who provided blood samples. Body measurements and blood pressure readings were done, and self-reported medical histories were taken.

The authors state, "These findings have important diagnostic and management implications. Patients who present with components of metabolic dysfunction should be routinely queried with respect to urological function, particularly voiding symptoms such as intermittency, incomplete emptying and nocturia, as well as the degree of associated bother. Sexual dysfunction symptoms, particularly erectile dysfunction, are similarly reported by the majority of men with MetS and should be routinely evaluated."

LUTS were assessed using the American Urological Association symptom index (AUASI), a clinically validated measure of urological symptoms. The AUASI was categorized into two groups as none or mild symptoms (AUASI less than 8) versus moderate or severe symptoms (AUASI 8 or greater). In this analysis MetS was defined as the presence of three or more of the five characteristics of 1) waist circumference greater than 102 cm; 2) systolic blood pressure 130 mm Hg or greater or diastolic blood pressure 85 mm Hg or greater, or antihypertensive medication use; 3) HDL cholesterol less than 40 mg/dl or lipid medication use; 4) self-reported type 2 diabetes or increased blood sugar or diabetes medication use; 5) triglycerides greater than 150 mg/dl.

An increased odds ratio of 1.68 for metabolic syndrome was observed in men with mild to severe LUTS symptoms compared to those with few or no symptoms. A statistically significant association was observed between the metabolic syndrome and a voiding symptom score of 5 or greater (odds ratio 1.73), but not for a storage symptom score of 4 or greater (odds ratio 0.94). Increased odds of the metabolic syndrome were observed even with mild symptoms, primarily for incomplete emptying, intermittency and nocturia. These associations were observed primarily in younger men (younger than 60 years) and were null in older men (60 years or older).

In an Editorial Comment accompanying the article Dr. Brett A. Laven, Clinic of Urology, Milwaukee, states that "The findings presented become increasingly significant as society weighs the costs of delivering health care to a population with an increased incidence of obesity/MetS. It has been estimated that more than 1 billion people are currently overweight and the prevalence in children has considerably increased. The possibility of pharmaceutically targeting the adipokine system, thus influencing a neuroendocrine pathway that might impact LUTS, is intriguing."


'/>"/>

Contact: Linda Gruner
jumedia@elsevier.com
212-633-3923
Elsevier Health Sciences
Source:Eurekalert

Related medicine news :

1. VIDEO: Cancer Treatment Centers of America Selects Site in GA for Proposed Hospital Serving Patients in Southeast
2. Omega-3 Fatty Acids Might Curb Depression in Heart Patients
3. House Bill to Provide Cancer Patients With Solution for Quality Cancer Care Within an Equitable Medicare Model
4. Patient Advocacy Groups Urge Greater Focus on Patients Choice and Privacy Rights in Health-Reform Debate
5. New findings encourage more vigilant monitoring of seizure activity among intensive care patients
6. Squeamish Colorado Dental Patients Get Drilled By Self-Interested Regulators
7. AMA Supports Health System Reform Alternatives Consistent With Principles of Pluralism, Freedom of Choice, Freedom of Practice and Universal Access for Patients
8. Lifelike Robot Provides Innovative Rehabilitation Treatment for Patients
9. Calling All Heart Patients
10. Telemedicine expands reach of care for Parkinsons patients
11. New Study Finds 1 in 4 Multiple Sclerosis Patients With High Out-of-Pocket Costs Not Filling Prescriptions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/24/2017)... ... January 23, 2017 , ... CLICKco ... and espresso drink, announced its CLICK® Coffee Protein Drink is now available for ... Drink Mix has become popular among health-conscious consumers who love coffee but are ...
(Date:1/24/2017)... (PRWEB) , ... January 23, 2017 , ... ... presence in Texas with the acquisitions of two personal care service companies: Padre ... Texas City, Texas, effective January 1, 2017. , Well regarded in their respective ...
(Date:1/23/2017)... ... January 23, 2017 , ... A Northwestern Pennsylvania addiction ... address. Alpine Springs Rehabilitation & Recovery Center’s new website can be found at ... with its redesigned and retooled website. The treatment center has also revamped its ...
(Date:1/23/2017)... (PRWEB) , ... January 23, 2017 , ... ... education and high-level training standards for healthcare treatment providers who treat the full ... its Presidents Council. , The Presidents Council consists of the leading eating ...
(Date:1/23/2017)... ... January 23, 2017 , ... Zachary Cattell, President of ... a healthcare industry expert at the 2017 Sector Summit hosted by Ivy Tech ... Business host Gerry Dick, will feature an employer and an association representative from ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... , Jan. 23, 2017  Based on its ... & Sullivan recognizes Ansell, a global leader in ... Sullivan Company of the Year Award. Ansell,s comprehensive ... a wide global footprint have placed it in ... protection market. The Company,s established product line and ...
(Date:1/23/2017)... , Jan. 23, 2017 MouthWatch LLC announced ... was ranked as the best intraoral camera on DentalCompare,s ... the #2 spot overall. The #1 product was the ... the MouthWatch intraoral camera was "…incredibly popular because it is ... camera has a small sticker price, it doesn,t sacrifice quality ...
(Date:1/23/2017)... Direct-to-consumer digital marketing strategy drives 85% ... in consumable sales, quarter-over-quarter ... ), a leader in digital health and mobile health ... Monitoring System, an all-in-one diabetes meter, today announced continued ... smart diabetes management solution. In just ...
Breaking Medicine Technology: