Navigation Links
Patients who use anti-depressants are more likely to suffer relapse, researcher finds
Date:7/19/2011

Patients who use anti-depressants are much more likely to suffer relapses of major depression than those who use no medication at all, concludes a McMaster researcher.

In a paper that is likely to ignite new controversy in the hotly debated field of depression and medication, evolutionary psychologist Paul Andrews concludes that patients who have used anti-depressant medications can be nearly twice as susceptible to future episodes of major depression.

Andrews, an assistant professor in the Department of Psychology, Neuroscience & Behaviour, is the lead author of a new paper in the journal Frontiers of Psychology.

The meta-analysis suggests that people who have not been taking any medication are at a 25 per cent risk of relapse, compared to 42 per cent or higher for those who have taken and gone off an anti-depressant.

Andrews and his colleagues studied dozens of previously published studies to compare outcomes for patients who used anti-depressants compared to those who used placebos.

They analyzed research on subjects who started on medications and were switched to placebos, subjects who were administered placebos throughout their treatment, and subjects who continued to take medication throughout their course of treatment.

Andrews says anti-depressants interfere with the brain's natural self-regulation of serotonin and other neurotransmitters, and that the brain can overcorrect once medication is suspended, triggering new depression.

Though there are several forms of anti-depressants, all of them disturb the brain's natural regulatory mechanisms, which he compares to putting a weight on a spring. The brain, like the spring, pushes back against the weight. Going off antidepressant drugs is like removing the weight from the spring, leaving the person at increased risk of depression when the brain, like the compressed spring, shoots out before retracting to its resting state.

"We fou
'/>"/>

Contact: Wade Hemsworth
hemswor@mcmaster.ca
905-525-9140
McMaster University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. ICU Patients at Risk for Rare Heart Rhythm Problem
2. Young patients with chronic illnesses find relief in acupuncture
3. For Some Breast Cancer Patients, Shorter Radiation Works Well
4. New Study Uses Adult Stem Cells in Effort to Save Limbs of Patients with Peripheral Arterial Disease
5. Patients with Lethal Lung Disease Finally Receive Recognition by Social Security Administration
6. Behavioral therapy improves sleep and lives of patients with pain
7. Protecting patients: Study shows that Johns Hopkins flu vaccination rates twice national average
8. MSU researcher linking breast cancer patients with alternative therapies
9. New American Heart Association Survey Finds Heart Disease and Stroke Patients Face Significant Barriers in Obtaining Quality, Affordable Care
10. Fishy Smell May Keep Patients From Diabetes Drug
11. AGA offers new recommendations for CRC surveillance for certain patients with IBD
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/9/2014)... have been linked to an emerging fungal disease ... Institute for Mathematical and Biological Synthesis (NIMBioS) shows ... , In a series of mathematical models, researchers ... internal organs in frogs, could cause extinction of ... exposed to the virus every few years, a ...
(Date:7/9/2014)... is one of the most important organs in the ... utilize our food properly this is its synthesis ... our organism this is its detoxification function. Lack ... food all damage the liver. The resulting diseased cells ... and life-threatening liver failure. According to the German Liver ...
(Date:7/9/2014)... , , , , ... , , , AUDIO: , ... approximately 30cm from the bullet... , , Click here for ... , , , , , ... , , , , , University of Southampton researchers, with assistance from the Ministry of ...
(Date:7/8/2014)... longevity and cardiovascular health as other healthy mature individuals, ... American Journal of Transplantation . The findings may provide ... transplant professionals caring for them. , Over the past ... years and older has become more common. Given the ... the removal of a kidney could make older donors ...
(Date:7/8/2014)... be three times higher when auditors were visible to ... according to a study in a major Canadian acute ... the Hawthorne effect in hand hygiene compliance monitoring using ... today on-line in the BMJ Quality & Safety ... did the study as part of her Master,s thesis ...
Breaking Medicine News(10 mins):Health News:Study predicts ranavirus as potential new culprit in amphibian extinctions 2Health News:Telemedicine for patients with chronic liver diseases 2Health News:Telemedicine for patients with chronic liver diseases 3Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 2Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 3Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 4Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 5Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 6Health News:Fit for the frontline? New study identifies the hearing requirements of British soldiers 7Health News:Study finds kidney donation safe for healthy older adults 2Health News:Health-care worker hand hygiene rates increase three-fold when auditors visible 2Health News:Health-care worker hand hygiene rates increase three-fold when auditors visible 3
... Health Partnership - It,s In Our Hands - Has Been ... Caregivers To Healthcare Resources And Services In Local Communities , ... Sanofi-aventis announced the initiation of its Community Health Partnership (CHP), ... seeking to link African American residents with local healthcare professionals ...
... Courage Center,s Transitional,Rehabilitation Program, which is licensed as ... the Stratis Health 2008-2011 Technical Assistance Group, a,learning collaborative ... is,supported by the federal Centers for Medicare & Medicaid ... Medicare Quality Improvement,Organization (QIO). , ...
... Turner as Chairman, Robert Schnitzius as Acting President & CEO ... DelSite, Inc. (OTC Bulletin Board: DSII.OB), a drug delivery technology ... directors for the Company, has resigned his position as chairman, effective ... until his term ends in May 2009. , ...
... Associates in Tropical Health (LATH), a consulting arm of ... 10 million contract to manage a programme of work ... in Malawi. , Led by the National Research ... year programme supported by the Wellcome Trust, the UK ...
... 11 Americans United for Life (AUL) today released ... addition of eight new guides this year, AUL now offers ... abortion, protection of unborn victims of violence, bioethics, healthcare rights ... Dr. Charmaine Yoest, AUL President & CEO said, ...
... this year,s Gottfried Wilhelm Leibniz Prize have been officially ... Committee of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) ... this year,s winners of Germany,s most prestigious research prize. ... 141 candidates. , The 2009 Gottfried Wilhelm Leibniz Prize ...
Cached Medicine News:Health News:Sanofi-aventis Partners with the African American Community in Baltimore to Increase Health Awareness, Access to Resources and Help Improve Patient Care 2Health News:Sanofi-aventis Partners with the African American Community in Baltimore to Increase Health Awareness, Access to Resources and Help Improve Patient Care 3Health News:Sanofi-aventis Partners with the African American Community in Baltimore to Increase Health Awareness, Access to Resources and Help Improve Patient Care 4Health News:Courage Center Transitional Rehabilitation Program to Participate in Learning Collaborative With Stratis Health 2Health News:DelSite Chairman George DeMott Resigns 2Health News:DelSite Chairman George DeMott Resigns 3Health News:LATH wins contract to boost health research capacity in Malawi 2Health News:Americans United for Life Releases Eight New Model Legislation & Policy Guides: Twenty-Three Model Legislation & Policy Guides Now Available 2Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 2Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 3Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 4Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 5Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 6Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 7Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 8Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 9Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 10Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 11Health News:The 2009 Leibniz Prize: Eleven new scientific discoverers 12
(Date:1/15/2014)... 2014  A novel wearable injector slightly larger than an Oreo ... to self-inject prescription drugs in the large doses required to ... autoimmune deficiencies, and genetic disorders.  An emerging ... 2018, according to analysts.   Many of these drugs will require ...
(Date:1/14/2014)... N.J. , Jan. 14, 2014 InformEx, ... and sellers of high-value chemistry, will hold the 30 th ... Miami Beach Convention Center from January 21-24. ... 3,500 attendees from top pharmaceutical, fine chemical and specialty chemical ...
(Date:1/14/2014)... 2014 /PRNewswire-iReach/ -- Acumed,s new SLIC Screw System - ... instrumentation to place and insert the screw accurately - ... (e.g. ligament) repair or reconstruction as it holds the ... (Photo: http://photos.prnewswire.com/prnh/20140114/MN45636 ) The SLIC ...
Breaking Medicine Technology:Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2Media Advisory: InformEx 2014 Events & Speaker Lineup for 30th Edition Conference in Miami Beach 2Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 2Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: