Navigation Links
Patients in Minimally Conscious State May Still Feel Pain
Date:10/7/2008

These brain-damaged individuals show signs of awareness, unlike vegetative state

TUESDAY, Oct. 7 (HealthDay News) -- Severely brain-damaged patients in a "minimally conscious state" may still feel pain and require painkilling treatment, according to European researchers.

A minimally conscious state (MCS) is different than a persistent vegetative state (PVS), which involves wakefulness without awareness of self or surroundings. MCS patients do show some evidence of awareness of self and their surroundings.

However, caregivers have difficulty assessing MCS patients' levels of conscious pain based on their behavior, according to background information in the study by Dr. Steven Laureys, of the Coma Science Group at the University of Liege, Belgium, and colleagues.

They compared brain activity following electrical stimulation of the median nerve in five MCS patients (ages 18 to 74), 15 PVS patients (ages 18 to 75), and 15 healthy people (ages 19 to 64). The researchers focused on brain areas responsible for pain sensation (the cortical pain matrix), including the thalamus, the primary somatosensory cortex, and the insular, frontoparietal and anterior cingulate cortices.

The MCS patients showed the same level of activity in these areas as healthy people and significantly more activity than PVS patients. The MCS patients also showed better "connectivity" between different brain regions responsible for pain than PVS patients.

"These findings might be objective evidence of a potential pain perception capacity in patients with MCS, which supports the idea that these patients need painkilling treatment," the researchers concluded.

The study was published online by The Lancet Neurology and was expected to be in the November print edition of the journal.

"Increased understanding of the neural processing that can take place in the absence of the conscious awareness, and the patterns of neural activity that are associated with volitional action and conscious experience will undoubtedly shed light on the mechanistic differences among the highly heterogeneous, but functionally restricted, population of patients with disorders of consciousness," Dr. John Whyte, of the Moss Rehabilitation Research Institute in Elkins Park, Pa., wrote in an accompanying comment.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about traumatic brain injury.



-- Robert Preidt



SOURCE: The Lancet Neurology, news release, Oct. 7, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New Center in Arizona Caters to Western U.S. Spine Patients
2. LegalView Informs Patients of Possible Cimzia Cancer Link, Drug Commonly Used to Treat Arthritis
3. News from Cancer: Disparities in head and neck cancer patients
4. Will patients stick to physical therapy? Questionnaire can help doctors predict
5. New Trend of Healthcare Companies Sending Patients Abroad for Surgery is Dangerous Says James Goldberg Whose Son Died Following Surgery in Thailand
6. MS patients have higher spinal fluid levels of suspicious immune molecule
7. Scams and Shams That Prey on Cancer Patients
8. VA, DoD Electronically Hand Off Records of Wounded Patients
9. Cancer patients who receive neoadjuvant therapy followed by mastectomy may not need radiation
10. How to select anti-hepatitis B virus agents for drug-resistance patients?
11. ALS Patients and Researchers Unite in Boston for 4th Annual Leadership Summit
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Patients in Minimally Conscious State May Still Feel Pain
(Date:3/28/2017)... ... March 29, 2017 , ... The Thyroid Secret is a ... FASCP. The program was recently launched on March 1, and Dr. Wentz discussed ... , Dr. Izabella Wentz is a licensed pharmacist and a foremost thyroid ...
(Date:3/28/2017)... ... March 28, 2017 , ... City trips ... (IBT World Travel Trends Report). As travelers visit both urban destinations, they are ... and prolonged sun exposure. In response, the outdoor industry has blurred the lines ...
(Date:3/28/2017)... ... March 28, 2017 , ... ... advancing the science and clinical practice of radiosurgery, announced today the publication ... multi-institutional, observational registry established to standardize data collection from patients treated with ...
(Date:3/28/2017)... ... ... Sentry Group LLC., a leader in the Personal Emergency Response System industry, introduced advanced ... These iSAFE products are the most affordable and most advanced medical alert systems on ... GPS Location and two-way calling with the push of a button on a nationwide ...
(Date:3/28/2017)... (PRWEB) , ... March 28, 2017 , ... WHO: , ... Toni Bark , WHAT: , Medical doctors and PhD scientists will speak to the ... to President Trump in support of an independent vaccine safety commission. , WHERE: ...
Breaking Medicine News(10 mins):
(Date:3/29/2017)... USA, March 29, 2017 Stryker announced today ... by People magazine, in partnership with Great Place to ... on the list. This list highlights the top U.S. ... in business while also demonstrating respect, compassion and concern ... To determine the companies on the list, ...
(Date:3/29/2017)... FinancialBuzz.com News Commentary  ... Data published in a research report by Grand View Research, ... of USD 55.8 billion by 2025. The projection takes into consideration the ... and a more open approach towards cannabis products around the world. In ... , North Dakota , Ohio , ...
(Date:3/29/2017)... , Mar. 29, 2017 Research and ... and Risk Management Software Market Outlook: 2016-2022" report to their ... The ... by product, mode of delivery, end-user, and geography. ... systems across the globe. The field has developed significantly in the ...
Breaking Medicine Technology: