Navigation Links
Patients in Minimally Conscious State May Still Feel Pain
Date:10/7/2008

These brain-damaged individuals show signs of awareness, unlike vegetative state

TUESDAY, Oct. 7 (HealthDay News) -- Severely brain-damaged patients in a "minimally conscious state" may still feel pain and require painkilling treatment, according to European researchers.

A minimally conscious state (MCS) is different than a persistent vegetative state (PVS), which involves wakefulness without awareness of self or surroundings. MCS patients do show some evidence of awareness of self and their surroundings.

However, caregivers have difficulty assessing MCS patients' levels of conscious pain based on their behavior, according to background information in the study by Dr. Steven Laureys, of the Coma Science Group at the University of Liege, Belgium, and colleagues.

They compared brain activity following electrical stimulation of the median nerve in five MCS patients (ages 18 to 74), 15 PVS patients (ages 18 to 75), and 15 healthy people (ages 19 to 64). The researchers focused on brain areas responsible for pain sensation (the cortical pain matrix), including the thalamus, the primary somatosensory cortex, and the insular, frontoparietal and anterior cingulate cortices.

The MCS patients showed the same level of activity in these areas as healthy people and significantly more activity than PVS patients. The MCS patients also showed better "connectivity" between different brain regions responsible for pain than PVS patients.

"These findings might be objective evidence of a potential pain perception capacity in patients with MCS, which supports the idea that these patients need painkilling treatment," the researchers concluded.

The study was published online by The Lancet Neurology and was expected to be in the November print edition of the journal.

"Increased understanding of the neural processing that can take place in the absence of the conscious awareness, and the patterns of neural activity that are associated with volitional action and conscious experience will undoubtedly shed light on the mechanistic differences among the highly heterogeneous, but functionally restricted, population of patients with disorders of consciousness," Dr. John Whyte, of the Moss Rehabilitation Research Institute in Elkins Park, Pa., wrote in an accompanying comment.

More information

The U.S. National Institute of Neurological Disorders and Stroke has more about traumatic brain injury.



-- Robert Preidt



SOURCE: The Lancet Neurology, news release, Oct. 7, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New Center in Arizona Caters to Western U.S. Spine Patients
2. LegalView Informs Patients of Possible Cimzia Cancer Link, Drug Commonly Used to Treat Arthritis
3. News from Cancer: Disparities in head and neck cancer patients
4. Will patients stick to physical therapy? Questionnaire can help doctors predict
5. New Trend of Healthcare Companies Sending Patients Abroad for Surgery is Dangerous Says James Goldberg Whose Son Died Following Surgery in Thailand
6. MS patients have higher spinal fluid levels of suspicious immune molecule
7. Scams and Shams That Prey on Cancer Patients
8. VA, DoD Electronically Hand Off Records of Wounded Patients
9. Cancer patients who receive neoadjuvant therapy followed by mastectomy may not need radiation
10. How to select anti-hepatitis B virus agents for drug-resistance patients?
11. ALS Patients and Researchers Unite in Boston for 4th Annual Leadership Summit
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Patients in Minimally Conscious State May Still Feel Pain
(Date:5/27/2016)... ... ... More than a third of American adults are considered obese, says the ... increased attention in recent years, as an article published May 18th on ... people are familiar with the basic requirements of maintaining a healthy diet and exercise ...
(Date:5/27/2016)... ... 27, 2016 , ... W.S. Badger Co. Inc ., the maker of ... recognized as one of the best small businesses for new dads by Fatherly, the ... small businesses providing progressive benefits to new parents on the organization’s 2016 Best ...
(Date:5/27/2016)... NY (PRWEB) , ... May 27, 2016 , ... This ... of a stroke, which we as a society can control and change. , As ... occurs nearly every 40 seconds within the United States. Plus, with an estimated 129,000 ...
(Date:5/27/2016)... ... 27, 2016 , ... Beleza Medspa has initiated a new program ... is the first time that Coolsculpting is being used for for more than just ... ensure they meet the prescribed body-fat standard, measured by the circumference-based tape method. ...
(Date:5/27/2016)... , ... May 27, 2016 , ... ... scholarships to students studying complementary medicine. Allison Outerbridge is this year’s Life ... award on May 18 at the university’s Student Leadership Awards ceremony. , Outerbridge ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... und GERMANTOWN, Maryland , May ... mit Therawis bedient dringenden ... QIAGEN N.V. (NASDAQ: QGEN ... eine Lizenz- und Entwicklungsvereinbarung mit Therawis Diagnostics GmbH ... Onkologie eingegangen zu sein. Ein erstes Projekt wird ...
(Date:5/25/2016)... SPRINGS, Florida , May 25, 2016 ... Business Conference & Expo earlier this month, the numbers ... As revenues continue to climb into the billions, more ... the newly released 4th Edition State of Legal Marijuana ... Frontier, a cannabis-focused data-analysis firm, much of the increase ...
(Date:5/25/2016)... PUNE, India , May 25, 2016 /PRNewswire/ ... Pipeline Review, H1 2016"market research report that provides ... complete with comparative analysis at various stages, therapeutics ... route of administration (RoA) and molecule type, along ... releases. It also reviews key players involved in ...
Breaking Medicine Technology: