Navigation Links
Patient Disparities Seen in Lung Cancer Drug Trials
Date:7/6/2011

WEDNESDAY, July 6 (HealthDay News) -- Women, older people and minorities are under-represented in lung cancer drug trials in the United States, according to a new study.

Researchers say that this could have a significant impact on the efficacy and safety of new treatments among these groups, particularly the elderly.

"Our results suggest that the trial population used for approval of drugs do not represent well the U.S. population who may receive the marketed agent," the study's principal investigator, Dr. Shakun Malik, a medical officer at the U.S. Food and Drug Administration in Silver Spring, Md., said in a news release.

"This fact is concerning particularly for older patients who may experience greater toxicity when given the same dose and combination of drugs based on testing in a younger population," Malik explained in the release from the International Association for the Study of Lung Cancer.

In conducting the study, which was slated for presentation Wednesday at the 14th World Conference on Lung Cancer in Amsterdam, researchers reviewed 10 years of trial data for the treatment of non-small cell lung cancer submitted to the U.S. Food and Drug Administration.

The study revealed that although 42 percent of patients diagnosed with lung cancer in the United States between 1975 and 2008 were women, only 32 percent of enrollees in 10 national and international drug trials for non-small cell lung cancer between 2000 and 2010 were women.

Moreover, although 73 percent of lung cancer patients in the United States are older than 65, only 36 percent of the drug trial population was in that age group.

Blacks also develop lung cancer at higher rates than whites, but they only comprised 2 percent of trial participants in the 10-year period, the study found. Meanwhile, researchers noted that whites made up 78 percent of enrollees, Asians comprised 15 percent, Hispanics 2 percent and "other" accounted f
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Elderly Dutch lung patients survival improved by new treatment options between 2003-2009
2. Patients at small, isolated, rural hospitals in US more likely to receive lower quality of care
3. ALK rearrangement found in nearly 10 percent of patients in Lung Cancer Mutation Consortium
4. Worse outcomes for older breast cancer patients with other health problems
5. Heart transplant patients at risk for serious skin cancers
6. Delaying Intravenous Feeding of ICU Patients May Aid Recovery
7. Research Sheds Light on Cause of Brain Deficits in HIV Patients
8. Patients treated with sunitinib and sorafenib respond to flu vaccine
9. Innovative UBC-BC Cancer Agency system reduces waitlisting for chemotherapy patients
10. Team approach reduces urinary tract infections in rehab patients
11. Intensive, hands-on effort reduces bloodstream infections in critically ill patients
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Patient Disparities Seen in Lung Cancer Drug Trials
(Date:4/1/2015)... 2015 It is the meat that has ... now found wrapped around other foods, infused into cocktails and ... meat candy, the gateway meat for vegetarians and the perfect ... North American Meat Institute (NAMI) has developed a new ... of a bacon processing plant and companion brochure ...
(Date:4/1/2015)... 2015 ScooterDirect.com is a one stop ... improve their customers’ lifestyle using electric mobility scooters, power ... needs of the people, they provide mobility scooters at ... independent and enjoy their freedom. Scooterdirect.com is offering Pride ... prices. , One of the team members ...
(Date:4/1/2015)... (PRWEB) April 01, 2015 Phybridge ... solutions infrastructure, announced today its strategic partnership with ... voice solutions to the businesses of Saskatchewan. SaskTels’ ... changing cross-platform application that offers users a hosted ... collaboration tools. The objective of IBC is ...
(Date:4/1/2015)... (PRWEB) April 01, 2015 Amada Senior ... living placement counseling, recently opened a new office in Rocky ... partners Tracy and Lee Bissett decided to make the move ... the area after over 20 years of experience in management ... April 2nd. , When asked what makes Amada ...
(Date:4/1/2015)... CA (PRWEB) April 01, 2015 TCS ... clinical solutions for the care management and population health ... the collaboration portal Acuity Connect, which is fully integrated ... April 15, 2015 at 1:30 p.m. ET, will be ... Development at TCS. It will explore the feature-rich portal ...
Breaking Medicine News(10 mins):Health News:New Ultimate Guide to Bacon Video Provides Inside Look at How Bacon is Made 2Health News:ScooterDirect.com Offering Pride Go Go Traveller Elite 3 Wheel Scooter 2Health News:Phybridge and SaskTel Team Up to Eliminate Network Barriers for IP Telephony and Unified Communications Migration 2Health News:Phybridge and SaskTel Team Up to Eliminate Network Barriers for IP Telephony and Unified Communications Migration 3Health News:Amada Senior Care Expands to Eastern North Carolina 2Health News:TCS Healthcare Technologies Releases Acuity Connect 2Health News:TCS Healthcare Technologies Releases Acuity Connect 3
... DETROIT, Aug. 13 Cancer deaths among people ... years because of better prevention measures, early detection efforts and ... Institute,s lead epidemiology researchers. , , (Logo: ... J. Graff, Ph.D., director of the Epidemiology Research Core at ...
... , , SILVER ... Health Laboratories (APHL) has been awarded $6.8 million in ... Relief (PEPFAR) to bolster the capabilities of laboratories and ... with the Global AIDS Program at the Centers for ...
... , , MENLO PARK, ... of the American College of Cardiology ( JACC ) indicates ... mitral regurgitation (MR) with sustained freedom from death, surgery or recurrent ... , , The published data is from the ...
... , , ISELIN, N.J., Aug. 12 Pharmos ... six-month period ended June 30, 2009. , , Second ... recorded a net loss of $2.3 million, or $0.05 per share, for the ... per share, in the second quarter 2008. Cash and cash equivalents totaled $2.9 ...
... research suggests , WEDNESDAY, Aug. 12 (HealthDay News) -- ... promise, a U.S. study shows. , The phase I ... with a form of Leber congenital amaurosis caused by ... gene is required for the production of a retina-specific ...
... , , , Dental ... Annual Session Courses , ... and the American Dental Education Association (ADEA) announce the launch of a ... access to select live-patient continuing education courses held at the 2009, 2010 ...
Cached Medicine News:Health News:Karmanos' Chief Cancer Surveillance Researcher Discusses Study on Decreased Cancer Mortality Rates 2Health News:Karmanos' Chief Cancer Surveillance Researcher Discusses Study on Decreased Cancer Mortality Rates 3Health News:APHL Chosen by PEPFAR to Develop Global Health Laboratory Systems 2Health News:EVEREST Data Demonstrates Acute Reduction of Mitral Regurgitation Without Procedural Mortality in Patients Treated With the MitraClip(R) Therapy 2Health News:EVEREST Data Demonstrates Acute Reduction of Mitral Regurgitation Without Procedural Mortality in Patients Treated With the MitraClip(R) Therapy 3Health News:EVEREST Data Demonstrates Acute Reduction of Mitral Regurgitation Without Procedural Mortality in Patients Treated With the MitraClip(R) Therapy 4Health News:Pharmos Corporation Reports 2009 Second Quarter Results 2Health News:Pharmos Corporation Reports 2009 Second Quarter Results 3Health News:Pharmos Corporation Reports 2009 Second Quarter Results 4Health News:Pharmos Corporation Reports 2009 Second Quarter Results 5Health News:Pharmos Corporation Reports 2009 Second Quarter Results 6Health News:Pharmos Corporation Reports 2009 Second Quarter Results 7Health News:Pharmos Corporation Reports 2009 Second Quarter Results 8Health News:Pharmos Corporation Reports 2009 Second Quarter Results 9Health News:Gene Therapy Offers Hope Against Inherited Blindness 2Health News:ADA and ADEA Launch Groundbreaking Education Project 2Health News:ADA and ADEA Launch Groundbreaking Education Project 3Health News:ADA and ADEA Launch Groundbreaking Education Project 4
(Date:4/1/2015)... Scientific Corporation (NYSE: BSX ) will webcast a conference ... to review financial results and business highlights for the first ... first quarter financial results prior to the conference call. ... , president and chief executive officer, and Dan Brennan ... A live webcast of the conference call will be available ...
(Date:4/1/2015)... BURNIE, Md. , April 1, 2015 /PRNewswire/ ... patient recruitment solutions for the clinical research industry, ... help with a dermatology study that was falling ... expert recruitment strategies and customized site support programs, ... screening and enrolling, and also increased the number ...
(Date:4/1/2015)... CREEK, Calif. , April 1, 2015  For ... huge difference.  When this is the case, having the ... No one understands this truth better than software solutions ... laboratory management software QATrax.  Recently, the company announced the ... very enthusiastic response from clients. ...
Breaking Medicine Technology:Boston Scientific To Webcast Conference Call On First Quarter 2015 Financial Results 2CSSi Quadruples Screening Activity and Speeds Enrollment for Pediatric Dermatology Study 2TraxStar Technologies Announces Latest QATrax Test Lab Management Software Now Available 2
... , RESEARCH TRIANGLE PARK, N.C. , ... ) announced today that the U.S. Food and Drug Administration ... add-on therapy for epilepsy in patients ages 13 years and ... label, as Lamictal XR is approved ...
... , , JOHNSTOWN, Pa. , Jan. 29 ... Company), (Pink Sheets: EPGL), ( www.eparent.com ), the parent company ... announce that Stephen L. DeFelice , MD, has joined the EPGL ... nutraceutical products and is credited for introducing the term "nutraceutical."  , ...
Cached Medicine Technology:FDA Approves Once-A-Day Lamictal(R)XR(TM) as Add-On Epilepsy Therapy for Primary Generalized Tonic-Clonic Seizures 2FDA Approves Once-A-Day Lamictal(R)XR(TM) as Add-On Epilepsy Therapy for Primary Generalized Tonic-Clonic Seizures 3FDA Approves Once-A-Day Lamictal(R)XR(TM) as Add-On Epilepsy Therapy for Primary Generalized Tonic-Clonic Seizures 4FDA Approves Once-A-Day Lamictal(R)XR(TM) as Add-On Epilepsy Therapy for Primary Generalized Tonic-Clonic Seizures 5FDA Approves Once-A-Day Lamictal(R)XR(TM) as Add-On Epilepsy Therapy for Primary Generalized Tonic-Clonic Seizures 6FDA Approves Once-A-Day Lamictal(R)XR(TM) as Add-On Epilepsy Therapy for Primary Generalized Tonic-Clonic Seizures 7EP Global Communications, Inc. Welcomes Stephen DeFelice, MD, to Advisory Board 2EP Global Communications, Inc. Welcomes Stephen DeFelice, MD, to Advisory Board 3
... a 16kDa peptide encoded by the ob gene ... believed to play a key role in the ... and expenditure [1,2]. Leptin functions as a lipostat ... increasing fat stores. Increased serum leptin levels signal ...
ACTIVATED CLOTTING TIME SYSTEM...
... Maximum image quality, accuracy and versatility. ... ACP Technology™, via our exclusive mPower™ whole ... is optimized to yield the highest quality ... In addition, the mPower™ is the only ...
... Human chorionic gonadotropin (hCG) is a two ... by the chorionic tissue of the placenta ... blood during pregnancy. Produced by the trophoblastic ... maintain the corpus luteum in the early ...
Medicine Products: