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Pathwork Diagnostics Launches Version of Its Tissue of Origin Test for FFPE Specimens
Date:1/13/2009

es, up to 10 percent are of tumor types not readily classifiable in the course of the initial diagnostic workup.(2) Tumors with uncertain origins are among the most frustrating for physicians and place a disproportionate burden on patients, healthcare professionals, and the healthcare system.

"Now that the Pathwork Tissue of Origin Test works with FFPE specimens, it will be more easily available for pathologists to utilize," said Dr. Larry Weiss, Chair, Division of Pathology, City of Hope. "When there is uncertainty about a tumor's origin, the Tissue of Origin Test holds the promise of delivering unique data not available through other methods, filling the information gap with accurate, objective, actionable information that may allow a patient's physician to make treatment decisions with greater confidence."

By utilizing the Tissue of Origin Test, physicians will be able to use objective criteria to identify the primary site of a tumor's origin, the first step in beginning standard-of-care, tumor-specific therapy per National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines. Targeting therapy to specific tumor types can also allow patients to avoid the toxicity of broader, and in some cases, ineffective chemotherapy. The test may also allow physicians to arrive at a diagnosis sooner, which can benefit cancer patients by enabling treatment to begin more quickly and allowing patients to enroll in and benefit from appropriate clinical trials.

With today's announcement, the Pathwork(R) Diagnostics Laboratory is now able to process and analyze both FFPE and frozen tissue specimens. Upon specimen receipt, Pathwork runs the microarray test on the specimens, and a staff pathologist interprets the test results and provides a comprehensive clinical report to the physician. Pathwork will seek FDA clearance for the FFPE version of the Tissue of Origin Test in an in vitro diagnostic (IVD) kit format so that pa
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SOURCE Pathwork Diagnostics, Inc.
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