Navigation Links
Particle Sciences Develops Zero-Order-Release Combination Device Technology

BETHLEHEM, Pa., Aug. 26 /PRNewswire/ -- Particle Sciences Inc. today announced the development of their "Microreservoir" technology enabling the manufacture of drug-eluting polymer medical devices that release drugs at constant rates over 30 days or more. This technology has already been used by Particles Sciences to develop drug eluting vaginal rings. "Drug release from polymeric materials often follows a burst/first-order kinetic profile which may not be clinically desired," explained Andrew Loxley, Director of New Technologies. "Traditionally the burst effect has been reduced by confining the API to a reservoir within the device, but this adds complexity and cost to production," he added. In their approach, Particle Sciences' scientists first encapsulate the drug in polymer microparticles before blending with the polymer used to make the final product. Robert Lee, VP of Pharmaceutical Development commented, "Microencapsulating the drug enabled the use of simple molding processes to fabricate devices containing tens of thousands of 'microreservoirs,' and the devices exhibit constant drug release profiles equivalent to traditional reservoir devices. This approach greatly simplifies production and adds tremendous flexibility to both single and multi-drug devices." Particle Sciences sees broad utility for this proprietary technology, which is applicable to polymer devices, films, coatings and other polymeric structures from which drugs or other materials are to be released at a constant rate. For more information on Particles Sciences, visit

Particle Sciences is an integrated provider of drug development services. Particle Sciences focuses on emulsions, gels, particulates and drug/device combination products with additional specialized capabilities in topical and mucosal drug delivery. Through a full range of formulation, analytic, and manufacturing services, Particle Sciences provides pharmaceutical companies with a complete and seamless development solution that minimizes the time and risk between discovery and the clinic. The company was founded in 1991 and is headquartered in Bethlehem, Pennsylvania.


Maureen Cochran


SOURCE Particle Sciences Inc.
Copyright©2008 PR Newswire.
All rights reserved

Related medicine news :

1. New disease-fighting nanoparticles look like miniature pastries
2. Nanoparticles + light = dead tumor cells
3. Using magenetic nanoparticles to combat cancer
4. Nanoparticle Stops Cancer From Spreading
5. Waves, particles and medicine in Houston
6. Smart bomb nanoparticle strategy impacts metastasis
7. MAP Pharmaceuticals Acquires Proprietary Drug Particle Formulation Technology From Eiffel/Telesso Technologies Limited
8. Nanoparticles aid bone growth
9. Magnetic nanoparticles: Suitable for cancer therapy?
10. Brown chemists create cancer-detecting nanoparticles
11. Scientists image a single HIV particle being born
Post Your Comments:
(Date:6/26/2016)... Michigan (PRWEB) , ... June 26, 2016 , ... On ... as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle ... honor of the city’s history as home to some of the world’s leading providers ...
(Date:6/26/2016)... Birmingham, Lake Orion, Clarkston, Michigan (PRWEB) , ... ... ... their direction with respect to fertility once they have been diagnosed with endometriosis. ... for tolerable intercourse but they also require a comprehensive approach that can help ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX ... Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package transforms over ... Cut Pro X . Simply select a ProHand generator and drag it above media ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary ... Work award to iHire in recognition of their exemplary accomplishments in worksite health promotion. ... Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire ...
(Date:6/24/2016)... Marne, Michigan (PRWEB) , ... June 24, 2016 , ... ... awareness about the dangers associated with chronic pain and the benefits of holistic treatments, ... for individuals who are suffering with Sickle Cell Disease. , Sickle Cell Disease (SCD) ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... Belgium , June 24, 2016 ... the appointment of Dr. Edward Futcher ... Non-Executive Director, effective June 23, 2016.Dr. Futcher was ... Nominations and Governance Committees.  As a non-executive member ... independent expertise and strategic counsel to VolitionRx in ...
(Date:6/23/2016)... , June 23, 2016  MedSource announced ... as its e-clinical software solution of choice.  This ... best possible value to their clients by offering ... The preferred relationship establishes nowEDC as the EDC ... for MedSource,s full-service clients.  "nowEDC has long been ...
(Date:6/23/2016)... June 23, 2016 Any dentist who has made ... the current process. Many of them do not even offer ... difficulties and high laboratory costs involved. And those who ARE ... at such a high cost that the majority of today,s ... Dr. Parsa Zadeh , founder of Dental Evolutions Inc. ...
Breaking Medicine Technology: