Navigation Links
Parkinson's disease risk greater in those exposed to trichloroethylene
Date:11/13/2011

A novel study in twins found that exposure to trichloroethylene (TCE) -- a hazardous organic contaminant found in soil, groundwater, and air -- is significantly associated with increased risk of Parkinson's disease (PD). Possibility of developing this neurodegenerative disease is also linked to perchloroethylene (PERC) and carbon tetrachloride (CCI4) exposure according to the study appearing today in Annals of Neurology, a journal published by Wiley-Blackwell on behalf of the American Neurological Association and Child Neurology Society.

The National Institute of Neurological Disorders and Stroke (NINDS) estimates that as many as 500,000 Americans have PD and more than 50,000 new cases are diagnosed annually. While there is much debate regarding cause of PD, studies suggest that genetic and environmental factors likely trigger the disease which is characterized by symptoms such as limb tremors, slowed movement, muscle stiffness, and speech impairment. Several studies have reported that exposure to solvents may increase risk of PD, but research assessing specific agents is limited.

The current epidemiological study, led by Drs. Samuel Goldman and Caroline Tanner with The Parkinson's Institute in Sunnyvale, California, investigated exposure to TCE, PERC and CCI4 and risk of developing PD. The team interviewed 99 twin pairs from the National Academy of Sciences/National Research Council World War II Veteran Twins Cohort in which one twin had PD and one didn't, inquiring about lifetime occupations and hobbies. Lifetime exposures to six specific solvents previously linked to PD in medical literature -- n-hexane, xylene, toluene, CCl4, TCE and PERC -- were inferred for each job or hobby.

The findings are the first to report a significant association between TCE exposure and PD -- a more than 6-fold increased risk. Researchers also found that exposure to PERC and CCI4 tended toward significant risk of developing the disease. "Our st
'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Abused girls may have higher risk of heart disease, stroke as adults
2. Abused Girls at Greater Risk for Heart Disease as Adults: Study
3. Kidney disease care -- whats in store for the future?
4. Which diabetes drug is best for diabetics with kidney disease?
5. Early, intensive therapy for type 1 diabetes prevented kidney disease in long-term study
6. Intensive therapy halves kidney disease in type 1 diabetes
7. Depression in young people increases risk of heart disease mortality
8. Cleveland Clinic nephrologist earns Federal grant for study of kidney disease management
9. Stem cell research hopes to repair brain damage of Parkinsons disease
10. Study finds shifting disease burden following universal Hib vaccination
11. Why do neurons die in Parkinsons disease?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/6/2015)... ... July 07, 2015 , ... Currently, mobile testing ... of AIDS, advances in the molecular diagnostic technologies, wide availability of immunosuppressive drugs ... detection technologies and genetic engineering also open lucrative opportunities for the market players. ...
(Date:7/6/2015)... ... 06, 2015 , ... Respected southern California personal injury attorney Fernando D. Vargas ... an attorney who has sharp legal skills as well as a superior commitment to ... from Martindale-Hubbell and a Top 10 Award from The National Academy of Personal Injury ...
(Date:7/6/2015)... , ... July 06, 2015 , ... “ TapGlance ” ... at the latest and coolest applications on the market for iOS, Android, and Windows. ... shared with viewers how this interior design app helps users visualize what rooms will ...
(Date:7/6/2015)... , ... July 06, 2015 , ... ... of orthopaedic sports medicine, the American Orthopaedic Society for Sports Medicine ( AOSSM ... July 9-12 in Orlando, FL. As a leader in orthopaedic sports medicine, ...
(Date:7/6/2015)... ... July 06, 2015 , ... Shortly after opening her second practice in Signal ... doctors working on a lien basis. Dr. Lim had previously worked with Dr. ... two Cambodian refugees, Dr. Lim suffered with back pain herself throughout high school. ...
Breaking Medicine News(10 mins):Health News:World Infectious Disease Testing Market Examined by VPGMarketResearch.com in In-Demand Report Available at MarketPublishers.com 2Health News:World Infectious Disease Testing Market Examined by VPGMarketResearch.com in In-Demand Report Available at MarketPublishers.com 3Health News:Fernando D. Vargas Awarded Top Honors in Personal Injury Law for 2015 from Two Respected Independent Organizations 2Health News:Fernando D. Vargas Awarded Top Honors in Personal Injury Law for 2015 from Two Respected Independent Organizations 3Health News:Create a Space with TapGlance, a Revolutionary Interior Design Application 2Health News:American Orthopaedic Society for Sports Medicine (AOSSM) Presents Prestigious Research Awards at Annual Meeting 2Health News:American Orthopaedic Society for Sports Medicine (AOSSM) Presents Prestigious Research Awards at Annual Meeting 3Health News:American Orthopaedic Society for Sports Medicine (AOSSM) Presents Prestigious Research Awards at Annual Meeting 4Health News:American Orthopaedic Society for Sports Medicine (AOSSM) Presents Prestigious Research Awards at Annual Meeting 5Health News:American Orthopaedic Society for Sports Medicine (AOSSM) Presents Prestigious Research Awards at Annual Meeting 6Health News:Respected Chiropractor Opens Office in Signal Hill/Cambodia Town and Joins Doctors on Liens 2
... Lab 1959 nuclear reactor meltdown has been reported to ... infamous// Three Mile Island accident according to studies presented ... advisory panel and are contradictory to years of assertions ... was released during the meltdown, thereby causing no public ...
... today received approval from the U.S. Food and Drug ... for the treatment of cutaneous T-cell lymphoma (CTCL) type ... returns during or after treatment with other medicines. ... Drug program that offers companies financial incentives to develop ...
... been a sharp rise in the number of HIV cases in Victoria ... since the early 1990s//. ,In Victoria, nearly 200 new HIV ... an increase of 38% than at the same time last year. 129 ... ,The numbers have been on the rise since 1999, however, it rose ...
... A distraught mother underwent sheer misery, caught between the devil ... daughter who was in dire need of emergency mental// healthcare. ... hold for a year, before any form of counseling was ... she had a history of two suicide attempts. According ...
... has made no bones about the government's lackluster response to ... the MCD have been// ordered to file an affidavit within ... Action plan was provided Rs 11372 cr to take appropriate ... seems to have been done. Despite Rs 21 cr being ...
... Siamese twins born with three legs and three arms on ... Friday, a health official said//. ,"It's a tough case, ... medical treatment at Sanglah Hospital in the Bali capital Denpasar, ... we haven't decided to take any action yet," he said, ...
Cached Medicine News:Health News:Simi Valley Nuclear Meltdown Effects Greater than Suspected 2Health News:Simi Valley Nuclear Meltdown Effects Greater than Suspected 3Health News:FDA Gives Approval for Skin Cancer Drug, Zolinza 2
(Date:7/6/2015)... 6, 2015  Impax Laboratories, Inc. (NASDAQ: IPXL ... second quarter 2015 financial results on Monday, August 10, ... markets. The Company will host a conference call and ... Eastern Time on August 10, 2015. The ... the Investor Relations section of the Company,s Web site ...
(Date:7/6/2015)... HORSHAM, Pa. , July 6, 2015 /PRNewswire/ ... procedure-based, bone fixation concept the FlowerCube™, announced today ... approval opens the opportunity for significant expansion of ...   The approval encompasses Flower Orthopedics, ... fixation solutions for upper and lower extremities. Consisting ...
(Date:7/6/2015)... NEWTOWN, Pa. , July 6, 2015 /PRNewswire/ ... services and technology provider, today announced that it ... retention firm, MediciGroup ® , Inc. (Medici).  The ... Access to Patients, LLC.  Medici also provides a ... finds missing patients globally.  Together with Medici, ...
Breaking Medicine Technology:Impax to Report Second Quarter 2015 Results on August 10, 2015 2Flower Orthopedics cleared to enter the European Union 2BioClinica Acquires MediciGroup 2BioClinica Acquires MediciGroup 3
... presented this week at the International Federation of Clinical ... lower diagnostic threshold for troponin improves clinical outcomes and ...  Troponin is a protein found inside of heart cells ... or reduced blood supply.   Cardiac troponin ...
... Neuro Kinetics, Inc. (NKI) ( www.neuro-kinetics.com ), ... for neuro-physiologic, neuro-otologic, vestibular and neurological testing, said ... its VEST™ control and analysis software. ... software to conduct vestibular, oculomotor and optokinetic tests ...
Cached Medicine Technology:Study Shows Improved Patient Management and Outcome Using Abbott's Sensitive Troponin Assay 2Study Shows Improved Patient Management and Outcome Using Abbott's Sensitive Troponin Assay 3Study Shows Improved Patient Management and Outcome Using Abbott's Sensitive Troponin Assay 4Neuro Kinetics Releases Updated Version of Neuro-Otologic Control and Analysis Software 2
VG1 ALIF (Anterior Lateral) Anterior lumbar interbody fusion. Frozen freeze-dried preservation....
Allograft implants can be easily used to repair and promote the healing of a wide variety of bone and other tissue defects....
Allograft implants can be easily used to repair and promote the healing of a wide variety of bone and other tissue defects....
Duet Lumbar Allografts are comprised of a raised cancellous inner core providing biomechanical properties for rapid healing. Specially designed instruments facilitate the insertion of Duet Allografts...
Medicine Products: