Navigation Links
Parkinson's Patients Still Prescribed Antipsychotics Despite Warning
Date:7/11/2011

MONDAY, July 11 (HealthDay News) -- Antipsychotic drugs are still prescribed to more than half of U.S. patients with Parkinson's disease and psychosis even though a warning that these drugs can worsen Parkinson's symptoms was issued six years ago, a new study reveals.

Many Parkinson's disease patients, including as many as 45,000 in the United States, eventually develop psychosis, meaning their thoughts are sometimes disconnected from reality. Parkinson's disease is also associated with dementia and complications of that condition, which may be exacerbated by antipsychotic drugs, according to the researchers.

In 2005, the U.S. Food and Drug Administration ordered antipsychotic drug packages to carry a "black box" warning about the risks the drugs pose to Parkinson's patients.

In the new study, published in the July issue of the journal Archives of Neurology, researchers analyzed Veterans Affairs data from 2002 to 2008 to assess antipsychotic drug prescription rates among 1,804 Parkinson's disease patients without dementia, 793 Parkinson's patients with dementia, and 6,907 patients with dementia and psychosis but no Parkinson's disease.

The investigators found that about half of the patients with Parkinson's disease and psychosis received an antipsychotic drug prescription. Use of the drugs was higher among patients with both Parkinson's disease and dementia than among those without dementia.

Between 2002 and 2008, the overall rate of antipsychotic prescriptions for Parkinson's patients was unchanged despite the warnings issued in 2005, but there was a decrease in the use of some antipsychotic drugs and an increase in the use of others, Dr. Daniel Weintraub, of the University of Pennsylvania, and colleagues noted in a journal news release.

"Approximately one-third of our Parkinson's disease sample had comorbid dementia, and many more likely had mild cognitive impairment," the authors wrote. "This has significant clinical implications in Parkinson's disease given the increased morbidity and mortality associated with typical and atypical [antipsychotic drug] use in dementia populations."

Even though prescribing habits appeared to shift toward antipsychotic drugs that are better tolerated by Parkinson's disease patients, those drugs are not necessarily safer or more effective, the researchers noted.

The researchers called for further studies to learn more about the factors that contribute to both overall and specific antipsychotic drug use in Parkinson's patients and to examine the effects of antipsychotic drug treatment on illness, death and disease progression in Parkinson's disease patients.

More information

We Move has more about Parkinson's disease.

-- Robert Preidt

SOURCE: Archives of Neurology, news release, July 11, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. ICU Patients at Risk for Rare Heart Rhythm Problem
2. Young patients with chronic illnesses find relief in acupuncture
3. For Some Breast Cancer Patients, Shorter Radiation Works Well
4. New Study Uses Adult Stem Cells in Effort to Save Limbs of Patients with Peripheral Arterial Disease
5. Patients with Lethal Lung Disease Finally Receive Recognition by Social Security Administration
6. Behavioral therapy improves sleep and lives of patients with pain
7. Protecting patients: Study shows that Johns Hopkins flu vaccination rates twice national average
8. MSU researcher linking breast cancer patients with alternative therapies
9. New American Heart Association Survey Finds Heart Disease and Stroke Patients Face Significant Barriers in Obtaining Quality, Affordable Care
10. Fishy Smell May Keep Patients From Diabetes Drug
11. AGA offers new recommendations for CRC surveillance for certain patients with IBD
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Parkinson's Patients Still Prescribed Antipsychotics Despite Warning
(Date:6/26/2016)... ... ... legally blind and certified personal trainer is helping to develop a weight loss fitness plan ... fix the two major problems leading the fitness industry today:, , ... They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily ... of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures ... . Simply select a ProHand generator and drag it above media or text in ...
(Date:6/25/2016)... ... 25, 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s ... setting the bar too high can result in disappointment, perhaps even self-loathing. However, those ... goal. , Research from PsychTests.com reveals that behind the tendency to ...
(Date:6/24/2016)... , ... June 24, 2016 , ... ... and Scientific Sessions in Dallas that it will receive two significant new grants ... grants came as PHA marked its 25th anniversary by recognizing patients, medical professionals ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening ... Talker Award, an essay contest in which patients and their families pay tribute to ... at the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... SAN CLEMENTE, Calif. , June 24, 2016 /PRNewswire/ ... pulmonary function testing company, is now able to perform sophisticated lung ... ndd Medical Technologies , Inc. Patients are ... labs.  Thanks to ndd,s EasyOne PRO ® , ARL patients like ... any needed testing done in the comfort of her own home. ...
(Date:6/24/2016)... Belgium , June 24, 2016 ... the appointment of Dr. Edward Futcher ... Non-Executive Director, effective June 23, 2016.Dr. Futcher was ... Nominations and Governance Committees.  As a non-executive member ... independent expertise and strategic counsel to VolitionRx in ...
(Date:6/23/2016)... , June 23, 2016 Any dentist who ... challenges of the current process. Many of them do not ... the technical difficulties and high laboratory costs involved. And those ... offer it at such a high cost that the majority ... Dr. Parsa Zadeh , founder of Dental ...
Breaking Medicine Technology: