Navigation Links
Parkinson's Patients Experience Declines Years Before Diagnosis
Date:7/6/2012

FRIDAY, July 6 (HealthDay News) -- Parkinson's disease patients experience declines in physical abilities and quality of life several years before the degenerative disease is diagnosed, new research finds.

In women, the declines started about 7.5 years before diagnosis, while in men, declines were noted at three years prior to diagnosis, according to the study in the June 2 issue of the Journal of Parkinson's Disease.

Parkinson's disease occurs when the neurons that produce dopamine, a crucial brain chemical, in certain regions of the brain die. Symptoms, which worsen over time, can include tremors, stiffness, slurred speech and trouble walking.

Researchers examined information on 51,000 men enrolled in the Health Professionals Follow Up Study and 122,000 women enrolled in the Nurses' Health Study.

The men completed questionnaires about their health-related quality of life, including physical functioning, limitations due to physical and emotional problems, mental health issues and pain. The women answered questions about their physical functioning.

Researchers identified 454 men and 414 women with Parkinson's disease. Until about 7.5 years before diagnosis, physical function for both men and women was similar to that of men and women who were not later diagnosed with Parkinson's.

From this point on, however, women with the disease began to experience a decline in their physical function, while men's decline in physical function and well-being began around three years prior to diagnosis.

"We observed a decline in physical function in [Parkinson's disease] patients relative to their healthy counterparts beginning three years prior to diagnosis in men and seven and a half years prior to diagnosis in women," study lead investigator Natalia Palacios, of Harvard School of Public Health, said in a journal news release. "The decline continues at a rate that is five to seven times faster than the average yearly decline caused by normal aging in individuals without the disease."

Researchers said the study suggests that the Parkinson's disease process may start years before symptoms become obvious.

"This result provides support to the notion that the pathological process leading to PD [Parkinson's disease] may start several years before PD diagnosis," Palacios concluded. "Our hope is that, with future research, biological markers of the disease process may be recognizable in this preclinical phase."

More information

The U.S. National Institute on Neurological Disorders and Stroke provides more information on Parkinson's disease.

-- Mary Elizabeth Dallas

SOURCE: Journal of Parkinson's Disease, news release, July 2, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Extra Pounds May Offer Protection to Heart Failure Patients
2. Fingolimod: Hint of advantages in a small group of patients
3. Obesity, larger waist size associated with better outcomes in heart failure patients
4. Northwestern launches comprehensive program for patients with bicuspid aortic valve disease
5. Botox May Ease Tremors in Multiple Sclerosis Patients
6. ACP Immunization Advisor app makes it easier for doctors to identify vaccines for patients
7. A better way to test new treatments? Approach could help patients and give useful results
8. Years before diagnosis, quality of life declines for Parkinsons disease patients
9. Virtual Colonoscopy Safe, Effective for Medicare Patients: Study
10. Analysis of KRYSTEXXA phase III data demonstrates improved health-related quality of life and physical function in refractory chronic gout patients
11. Few Patients Should Get Metal-on-Metal Hip Implants, FDA Panel Says
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... ... Talented host, actor Rob Lowe, is introducing a segment ... of "Success Files," which is an award-winning educational program broadcasted on PBS Member ... with passion and integrity. , Sciatica occurs when the sciatic nerve in the ...
(Date:10/13/2017)... ... , ... “The Journey: From the Mountains to the Mission Field”: the story ... the Philippines. “The Journey: From the Mountains to the Mission Field” is the creation ... has taught all ages and currently teaches a class of ladies at her church, ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... for healthcare compliance program management, will showcase a range of technology and learning ... Assisted Living (NCAL) Convention and Expo to be held October 14–18, 2017 at ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and fastest ... to open a flagship location in Covington, LA at 401 N. U.S. Highway 190, ... next to Office Depot in the Holiday Square shopping center. Its location allows it ...
(Date:10/12/2017)... ... 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), one of ... innovative new design of the shoulder pad. The shoulder pad provides optimal support ... your pain while using cold therapy. By utilizing ice and water that is circulated ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... Oct. 12, 2017 AVACEN Medical , Inc. ... with their  2017 New Product Innovation Award for Its ... primary and secondary medical device market research by Frost & ... first-to-market OTC, drug-free pain relief product, the AVACEN 100, offers ... treating fibromyalgia widespread pain. ...
(Date:10/11/2017)... Oct. 11, 2017  BioPharmX Corporation (NYSE MKT: BPMX) ... developed an innovative way to use nonlinear optical imaging ... of new drugs. ... Conference will show how researchers from BioPharmX and the ... School used a suite of imaging techniques in what ...
(Date:10/11/2017)... 11, 2017  Hill-Rom Holdings, Inc. ("Hill-Rom") (NYSE: HRC), ... in Las Piedras, Puerto Rico , ... Following a ... sustained minor structural damage, temporary loss of power and ... been completed, manufacturing operations have resumed, and the company ...
Breaking Medicine Technology: