Navigation Links
Parkinson's Drugs Can Trigger Unhealthy Behaviors
Date:4/10/2009

But lower doses of dopamine agonists appear to curb compulsive acting out, study says

FRIDAY, April 10 (HealthDay News) -- A class of Parkinson's disease drugs called dopamine agonists can cause patients to develop destructive behaviors such as compulsive gambling or hypersexuality, says a new study.

Mayo Clinic researchers found that one in six patients taking therapeutic doses of dopamine agonists, such as pramipexole and ropinirole, developed unhealthy behaviors. But decreasing the dosage of these drugs may eliminate the problem.

For their study, the researchers analyzed the medical records of 267 Parkinson's disease patients treated at the Mayo Clinic in Rochester, Minn., between 2004 and 2006. Of those patients, 66 were taking dopamine agonists, including 38 who were taking therapeutic doses (doses expected to be at least minimally beneficial).

Seven of the 38 patients taking therapeutic doses of dopamine agonists developed compulsive gambling or hypersexuality after they started taking the drugs. None of the other Parkinson's patients developed those destructive behaviors, including the 28 patients taking subtherapeutic doses of dopamine agonists, or the 178 patients taking carbidopa/levodopa, the standard drug for Parkinson's.

The study is published in the April issue of Mayo Clinic Proceedings.

"It is crucial for clinicians prescribing dopamine agonists to apprise patients as well as their spouses or partners about this potential side effect. The onset can be insidious and overlooked until life-altering problems develop," Dr. J. Eric Ahlskog, a Mayo Clinic neurologist, said in a clinic news release. "It also is worth noting that the affected patients were all taking therapeutic doses. Very low doses, such as those used to treat restless legs syndrome, carry much less risk."

"For some patients, a reduction in the dose of the dopamine agonist may prove to be sufficient treatment, although total elimination of the offending drug is often necessary," Ahlskog added.

More information

We Move has more about treatments for Parkinson's disease.



-- Robert Preidt



SOURCE: Mayo Clinic, news release, April 8, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Test quickly assesses whether Alzheimers drugs are hitting their target
2. Patient Movement Forms in Opposition to FDA Position that the Patient's Own Stem Cells are Drugs
3. Private-label OTC Drugs Post Solid Gains in 2008, According to Kline
4. Certain Diabetes Drugs May Pose Eye Risk
5. Breakthrough model for human cancer may improve development of cancer drugs; study in PNAS
6. More U.S. Kids Taking Diabetes, Blood Pressure Drugs
7. Link between widely used osteoporosis drugs and heart problems probed
8. Interviewed Experts Expect Taxotere to Increase Overall Survival More Than Other Drugs, Including Lupron Depot, in Stage III Prostate Cancer
9. Researchers question effectiveness of warning labels on over-the-counter drugs
10. Patients Say MPM Medicals Regenecare Gel Significantly Reduced the Itching and Pain of Skin Rashes Triggered by Anti-Cancer Drugs
11. IROs Help Decide Medically on Approved Uses of Off-Label Drugs for Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Parkinson's Drugs Can Trigger Unhealthy Behaviors
(Date:2/12/2016)... ... February 12, 2016 , ... ... Care.” , The print component of “Revolutionizing Cancer Care” is distributed ... York, Washington DC/Baltimore, and Seattle, with a circulation of approximately 250,000 copies and ...
(Date:2/12/2016)... ... February 12, 2016 , ... A lot has been reported about ... president has access to health and wellness resources most Americans could ever dream of ... individual has a schedule as frenetic as the U.S. President. , In honor ...
(Date:2/12/2016)... ... February 12, 2016 , ... Basketball is a game for everyone, not ... Peety PoppersTM series, sign language translation is featured in the top right of the ... Peety PoppersTM lessons has a sign language translator to teach kids the game and ...
(Date:2/11/2016)... ... 11, 2016 , ... “ HEALING MIND : Five Steps to Ultimate ... by Balboa Press) teaches readers how to become their own therapist. Providing a useful ... McDermott, M.Ed., LCSW, offers an understanding of how to heal one’s inner child using ...
(Date:2/11/2016)... ... 11, 2016 , ... Dr. Sadati’s recent feature in Allure ... with performing procedures, the magazine also highlights that Dr. Sadati has pioneered new ... the most common procedures he performs is his natural facelift. “As people age, ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... , Feb. 11, 2016  Kindred Biosciences, Inc. ... saving and improving the lives of pets, today announced ... of the New Animal Drug Application (NADA) for Zimeta™ ... field study (KB0120) of Zimeta for the control of ... Company. --> --> ...
(Date:2/11/2016)... -- Potrero Medical, Inc., the developer of the Accuryn™ critical ... George M. Rapier, III , MD, to its Board ... WellMed is one of the nation,s largest physician owned practice ... Texas and Florida ... internal medicine practice, he has been instrumental to the company,s ...
(Date:2/11/2016)... Feb. 11, 2016  AfterPill.com is reporting that this ... abstinence for all women who are at risk of ... each year and raises the risks of unprotected sex ... --> According to the Guttmacher Institute, there are ... of child-bearing age, who have sex without the intention ...
Breaking Medicine Technology: