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Parent Project Muscular Dystrophy Awards Two End Duchenne Grants
Date:5/5/2009

s the reason we created the End Duchenne Grant Award Program. If we can help both Dr. Vandenborne and Dr. Spencer maintain the momentum of these important avenues in treatment, so that they can receive funding from the NIH in the near future, then we will consider this grant program a huge success."

Dr. Vandenborne is delighted that the University of Florida -- Gainesville will receive the support of PPMD and said, "It is an honor to receive this grant and to know that the PPMD review committee feels as strongly about the promise of MRI and MRS as a non-invasive outcome measure for Duchenne. If we can replace biopsies as a tool to monitor efficacy in clinical trials for Duchenne with these methods, I think we will be able to greatly accelerate the translation from pre-clinical animals studies to clinical trials."

UCLA's Melissa Spencer is also excited about the potential this grant gives her work. "Ms. Furlong and the grant committee understand the potential of Osteopontin to help reduce inflammation and fibrosis in Duchenne, and they are willing to show their support financially. I can think of no greater compliment than to have an organization, as conscientious and dedicated to ending Duchenne as PPMD, support our research at UCLA."

The End Duchenne Grant Award Program was designed to enable investigators to continue their projects and generate additional data for a successful re-application within a 12 to 24 month period, thus leveraging additional Duchenne-specific research dollars.

Duchenne, the most common form of childhood muscular dystrophy, is a progressive and fatal muscle disorder affecting boys and young men that causes the loss of muscle function, wheelchair dependency and a decline in respiratory and cardiac function.

An applicant seeking support from the End Duchenne Grant Award Program must be employed at a for-profit or non-profit o
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SOURCE Parent Project Muscular Dystrophy
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